Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andreas Radek"'
Autor:
Victoria Steffen, Julia Otten, Susann Engelmann, Andreas Radek, Michael Limberg, Bernd W. Koenig, Stephan Noack, Wolfgang Wiechert, Martina Pohl
Publikováno v:
Sensors, Vol 16, Iss 10, p 1604 (2016)
Background: The fast development of microbial production strains for basic and fine chemicals is increasingly carried out in small scale cultivation systems to allow for higher throughput. Such parallelized systems create a need for new rapid online
Externí odkaz:
https://doaj.org/article/4f5409efc5d1424b80fc562a14855577
The myo-inositol/proton symporter IolT1 contributes to d-xylose uptake in Corynebacterium glutamicum
Autor:
Niklas Tenhaef, Andreas Radek, Karin Krumbach, Christian Brüsseler, Stephan Noack, Jan Marienhagen
Publikováno v:
Bioresource Technology. 249:953-961
Corynebacterium glutamicum has been engineered to utilize d -xylose as sole carbon and energy source. Recently, a C. glutamicum strain has been optimized for growth on defined medium containing d -xylose by laboratory evolution, but the mutation(s) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b590c872187ac54abe0854ee7dbc80
https://doi.org/10.1016/j.biortech.2017.10.098
https://doi.org/10.1016/j.biortech.2017.10.098
Autor:
Moritz-Fabian Müller, Karin Krumbach, Andreas Radek, Jan Marienhagen, Stephan Noack, Lothar Eggeling, Jochem Gätgens
Publikováno v:
Journal of Biotechnology. 231:160-166
Wild-type Corynebacterium glutamicum has no endogenous metabolic activity for utilizing the lignocellulosic pentose d-xylose for cell growth. Therefore, two different engineering approaches have been pursued resulting in platform strains harbouring a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7364adff01d211d5e85b15edf2fe3d
https://doi.org/10.1016/j.jbiotec.2016.06.009
https://doi.org/10.1016/j.jbiotec.2016.06.009
Autor:
Andreas Radek, Pornkamol Unrean, Niklas Tenhaef, Stephan Noack, René Hilmes, Christian Brüsseler, Jan Marienhagen
Publikováno v:
Bioresource technology. 268
It was found that Corynebacterium glutamicum ΔiolR devoid of the transcriptional regulator IolR accumulates high amounts of d -xylonate when cultivated in the presence of d -xylose. Detailed analyses of constructed deletion mutants revealed that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c215b6e15c263791095268c4f16f32
https://pubmed.ncbi.nlm.nih.gov/30092487
https://pubmed.ncbi.nlm.nih.gov/30092487
Autor:
Jörn Kalinowski, Andreas Radek, Niklas Tenhaef, Gerd M. Seibold, Stephan Hans, Natalie Brühl, Stephan Noack, R. Kloß, Andreas Küberl, Julia Frunzke, Volker F. Wendisch, Simon Unthan, Wolfgang Wiechert, Moritz Fabian Müller, Tino Polen, Christian Rückert, Michael Bott, Daniel Siebert, Kay Marin, Meike Baumgart, Reinhard Krämer
Publikováno v:
ACS synthetic biology 7(1), 132–144 (2018). doi:10.1021/acssynbio.7b00261
Targeted top-down strategies for genome reduction are considered to have a high potential for providing robust basic strains for synthetic biology and industrial biotechnology. Recently, we created a library of 26 genome-reduced strains of Corynebact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48043814c4436e443f8426128aca522
https://pubmed.ncbi.nlm.nih.gov/28803482
https://pubmed.ncbi.nlm.nih.gov/28803482
Autor:
Andreas Radek, Tino Polen, Moritz Fabian Müller, Christian Brüsseler, Niklas Tenhaef, Jan Marienhagen, Stephan Noack, Wolfgang Wiechert
Publikováno v:
Bioresource technology. 245
Adaptive Laboratory Evolution (ALE) is increasingly being used as a technique for untargeted strain optimization. This work aimed at developing an automated and miniaturized ALE approach based on repetitive batch cultivations in microtiter plates. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a24ad412bd5f004b96447ac5a57a557
https://pubmed.ncbi.nlm.nih.gov/28552568
https://pubmed.ncbi.nlm.nih.gov/28552568
Autor:
Gerd M. Seibold, Reinhard Krämer, Jörn Kalinowski, Natalie Brühl, Stephan Noack, Daniel Siebert, Michael Bott, Christian Rückert, Volker F. Wendisch, Simon Unthan, Wolfgang Wiechert, Stephan Hans, Kay Marin, Meike Baumgart, Anna Bartsch, Marius Herbst, Julia Frunzke, Andreas Radek
Publikováno v:
Biotechnology Journal
Biotechnology journal 10(2), 290-301 (2015). doi:10.1002/biot.201400041
Biotechnology journal 10(2), 290-301 (2015). doi:10.1002/biot.201400041
For synthetic biology applications, a robust structural basis is required, which can be constructed either from scratch or in a top-down approach starting from any existing organism. In this study, we initiated the top-down construction of a chassis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803eb18882bdc4a2ba9bd4763b395093
http://europepmc.org/articles/PMC4361050
http://europepmc.org/articles/PMC4361050
Autor:
Pohl, Victoria Steffen, Julia Otten, Susann Engelmann, Andreas Radek, Michael Limberg, Bernd Koenig, Stephan Noack, Wolfgang Wiechert, Martina
Publikováno v:
Sensors; Volume 16; Issue 10; Pages: 1604
Background: The fast development of microbial production strains for basic and fine chemicals is increasingly carried out in small scale cultivation systems to allow for higher throughput. Such parallelized systems create a need for new rapid online
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0f0b7abf45035fbcf9852b8fa4b19bd2
Publikováno v:
Microbial Cell Factories
Microbial cell factories 14(1), 32 (2015). doi:10.1186/s12934-015-0216-6
Microbial cell factories 14(1), 32 (2015). doi:10.1186/s12934-015-0216-6
Background: The throughput of cultivation experiments in bioprocess development has drastically increased in recent years due to the availability of sophisticated microliter scale cultivation devices. However, as these devices still require time-cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdb847f0f806d232f05ddd11ffdd5f4
http://europepmc.org/articles/PMC4361198
http://europepmc.org/articles/PMC4361198
Publikováno v:
Biotechnology for Biofuels
Biotechnology for biofuels 8(1), 31-(2015). doi:10.1186/s13068-015-0209-z
Biotechnology for biofuels 8(1), 31-(2015). doi:10.1186/s13068-015-0209-z
Background: Glycerol generated during renewable fuel production processes is potentially an attractive substrate for the production of value-added materials by fermentation. An engineered strain MITXM-61 of the oleaginous bacterium Rhodococcus opacus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d6d9d67aabecd8825bcffcebcdb36e
https://doi.org/10.1186/s13068-015-0209-z
https://doi.org/10.1186/s13068-015-0209-z