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pro vyhledávání: '"Andreas Präg"'
Publikováno v:
Chembiochem
Partially reduced aromatic polyketides are bioactive secondary metabolites or intermediates in the biosynthesis of deoxygenated aromatics. For the antibiotic GTRI‐02 (mensalone) in different Streptomyces spp., biosynthesis involving the reduction o
Autor:
Dennis Wetzl, Michael Müller, Sascha Ferlaino, Hans Iding, Steffen Lüdeke, Andreas Präg, Beat Wirz, Cindy Wechsler, Sebastian Roth, Marija Marolt, Nicolas Sandon
Publikováno v:
Chembiochem : a European journal of chemical biology. 18(17)
NADP(H)-dependent imine reductases (IREDs) are of interest in biocatalytic research due to their ability to generate chiral amines from imine/iminium substrates. In reaction protocols involving IREDs, glucose dehydrogenase (GDH) is generally used to
Autor:
Lisa Schneider, Andreas Präg, Oliver Einsle, Michael Müller, Stefan Gerhardt, Tobias B. Huber
Publikováno v:
ChemCatChem. 6:2248-2252
The importance and structural diversity of chiral amines is well-demonstrated by the myriad nonenzymatic methods for their chemical production. In nature, the production of amines is performed by transamination rather than by reduction of an imine pr
Autor:
Andriy Luzhetskyy, Steffen Lüdeke, Stefan Günther, Björn Grüning, Michael Müller, Michael Richter, Marta Luzhetska, Marcel Wilde, Andreas Präg, Matthias Häckh
Publikováno v:
Journal of the American Chemical Society. 136:6195-6198
Intermolecular oxidative phenol coupling is the main process in nature for the formation of atroposelective biaryl compounds. Although well defined in plants and fungi, this type of dimerization reaction in bacteria is poorly understood. Therefore, t