Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Andreas Pich"'
Autor:
Kevin Schmidt, Arne Schmidt, Sonja Groß, Annette Just, Angelika Pfanne, Maximilian Fuchs, Maria Jordan, Elisa Mohr, Andreas Pich, Jan Fiedler, Thomas Thum
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Beneficial effects of sodium glucose co-transporter 2 inhibitors (SGLT2is) in cardiovascular diseases have been extensively reported leading to the inclusion of these drugs in the treatment guidelines for heart failure. However, molecular ac
Externí odkaz:
https://doaj.org/article/0e2917f31446424496133fadf37d1b29
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S506- (2023)
Externí odkaz:
https://doaj.org/article/19b20532b590409984934f66d21f9d5c
Autor:
Baxolele Mhlekude, Dylan Postmus, Saskia Stenzel, January Weiner, Jenny Jansen, Francisco J Zapatero-Belinchón, Ruth Olmer, Anja Richter, Julian Heinze, Nicolas Heinemann, Barbara Mühlemann, Simon Schroeder, Terry C Jones, Marcel A Müller, Christian Drosten, Andreas Pich, Volker Thiel, Ulrich Martin, Daniela Niemeyer, Gisa Gerold, Dieter Beule, Christine Goffinet
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011657 (2023)
Inhibitors of bromodomain and extra-terminal proteins (iBETs), including JQ-1, have been suggested as potential prophylactics against SARS-CoV-2 infection. However, molecular mechanisms underlying JQ-1-mediated antiviral activity and its susceptibili
Externí odkaz:
https://doaj.org/article/68f2a8478fe7484fafc679780534d4ce
Autor:
Sebastian Roman Borgert, Steffi Henke, Florian Witzgall, Stefan Schmelz, Susanne zur Lage, Sven-Kevin Hotop, Steffi Stephen, Dennis Lübken, Jonas Krüger, Nicolas Oswaldo Gomez, Marco van Ham, Lothar Jänsch, Markus Kalesse, Andreas Pich, Mark Brönstrup, Susanne Häussler, Wulf Blankenfeldt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence of P. aeruginosa,
Externí odkaz:
https://doaj.org/article/0f0b91a8c4f34e998f22e33116f8f4b6
Autor:
Anne Kathrin Wessig, Leonie Hoffmeister, Annika Klingberg, Anika Alberts, Andreas Pich, Korbinian Brand, Torsten Witte, Konstantin Neumann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In gout, crystallization of uric acid in the form of monosodium urate (MSU) leads to a painful inflammatory response. MSU crystals induce inflammation by activating the complement system and various immune cell types, and by inducing necroti
Externí odkaz:
https://doaj.org/article/fc215984b77e49c793190607bdf5f93a
Autor:
Heike A. Schmitt, Andreas Pich, Nils K. Prenzler, Thomas Lenarz, Jennifer Harre, Hinrich Staecker, Martin Durisin, Athanasia Warnecke
Publikováno v:
ACS Omega, Vol 6, Iss 33, Pp 21241-21254 (2021)
Externí odkaz:
https://doaj.org/article/20af49b259614e70aaacb9f409e0f04b
Autor:
Stevan D. Stojanović, Maximilian Fuchs, Chunguang Liang, Kevin Schmidt, Ke Xiao, Annette Just, Angelika Pfanne, Andreas Pich, Gregor Warnecke, Peter Braubach, Christina Petzold, Danny Jonigk, Jörg H. W. Distler, Jan Fiedler, Thomas Thum, Meik Kunz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The family of RNA-binding proteins (RBP) functions as a crucial regulator of multiple biological processes and diseases. However, RBP function in the clinical setting of idiopathic pulmonary fibrosis (IPF) is still unknown. We developed a pr
Externí odkaz:
https://doaj.org/article/757334abd2ab4df69064526720aa8b80
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Nuclear and cytoplasmic actin-cofilin rods are formed transiently under stress conditions to reduce actin filament turnover and ATP hydrolysis. The persistence of these structures has been implicated in disease pathology of several neurologi
Externí odkaz:
https://doaj.org/article/8675360be3134e99aa21bbd472c74877
Autor:
Alina van Dieken, Hinrich Staecker, Heike Schmitt, Jennifer Harre, Andreas Pich, Willi Roßberg, Thomas Lenarz, Martin Durisin, Athanasia Warnecke
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The high complexity of the cellular architecture of the human inner ear and the inaccessibility for tissue biopsy hampers cellular and molecular analysis of inner ear disease. Sampling and analysis of perilymph may present an opportunity for improved
Externí odkaz:
https://doaj.org/article/42b21ee4ef42408fbd2b5355a6a56bbf
Autor:
Tim Becker, Andreas Pich, Stephanie Tamm, Silke Hedtfeld, Mohammed Ibrahim, Janine Altmüller, Nina Dalibor, Mohammad Reza Toliat, Sabina Janciauskiene, Burkhard Tümmler, Frauke Stanke
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Abstract SCNN1B encodes the beta subunit of the epithelial sodium channel ENaC. Previously, we reported an association between SNP markers of SCNN1B gene and disease severity in cystic fibrosis-affected sibling pairs. We hypothesized that factors int
Externí odkaz:
https://doaj.org/article/dcc752896878496ebfa52dadd5b3f362