Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Andreas Petri"'
Autor:
Tsinat Berhane, Anja Holm, Kasper Thystrup Karstensen, Andreas Petri, Mirolyuba Simeonova Ilieva, Henrik Krarup, Mogens Vyberg, Marianne Bengtson Løvendorf, Sakari Kauppinen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with increasing incidence in western countries. Most HCC patients have advanced cancer at the time of diagnosis due to the asymptomatic nature of early-stage HCC
Externí odkaz:
https://doaj.org/article/eea7838194aa4d789abf5565a533959d
Autor:
Riccardo Panella, Andreas Petri, Bhavna N. Desai, Sharmila Fagoonee, Cody A. Cotton, Piercen K. Nguyen, Eric M. Lundin, Alexandre Wagshal, Da-Zhi Wang, Anders M. Näär, Ioannis S. Vlachos, Eleftheria Maratos-Flier, Fiorella Altruda, Sakari Kauppinen, Pier Paolo Pandolfi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12870 (2023)
Obesity is a growing public health problem associated with increased risk of type 2 diabetes, cardiovascular disease, nonalcoholic fatty liver disease (NAFLD) and cancer. Here, we identify microRNA-22 (miR-22) as an essential rheostat involved in the
Externí odkaz:
https://doaj.org/article/47ccad04fd374b7c90bbd4d0800f2ef9
Autor:
Linda Vidarsdottir, Alireza Azimi, Ishani Das, Ingibjorg Sigvaldadottir, Aldwin Suryo Rahmanto, Andreas Petri, Sakari Kauppinen, Christian Ingvar, Göran Jönsson, Håkan Olsson, Marianne Frostvik Stolt, Rainer Tuominen, Olle Sangfelt, Katja Pokrovskaja Tamm, Johan Hansson, Dan Grandér, Suzanne Egyházi Brage, Per Johnsson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract BRAF inhibitors (BRAFi) selectively target oncogenic BRAFV600E/K and are effective in 80% of advanced cutaneous malignant melanoma cases carrying the V600 mutation. However, the development of drug resistance limits their clinical efficacy.
Externí odkaz:
https://doaj.org/article/f88ae22862f24b9684552bdca23e8edf
Autor:
Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, Sara Terreri, Eric Wang, Frances A. Collins, Lauren A. Woodward, Allison E. Walker, Deedra Nicolet, Felice Pepe, Prasanthi Kumchala, Marius Bill, Christopher J. Walker, Malith Karunasiri, Krzysztof Mrózek, Miranda L. Gardner, Virginia Camilotto, Nina Zitzer, Jonathan L. Cooper, Xiongwei Cai, Xiaoqing Rong-Mullins, Jessica Kohlschmidt, Kellie J. Archer, Michael A. Freitas, Yi Zheng, Robert J. Lee, Iannis Aifantis, George Vassiliou, Guramrit Singh, Sakari Kauppinen, Clara D. Bloomfield, Adrienne M. Dorrance, Ramiro Garzon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
LncRNAs at the HOX gene locus are increased in expression in NPM1 mutant acute myeloid leukemia. In this study, the authors show that one such lncRNA, HOX3B-AS3, has a role in regulating gene transcription and protein synthesis in leukemia cells.
Externí odkaz:
https://doaj.org/article/4362506e0cc14ab88f90e66fd4195bb2
Autor:
Kasper Thystrup Karstensen, Aleks Schein, Andreas Petri, Martin Bøgsted, Karen Dybkær, Shizuka Uchida, Sakari Kauppinen
Publikováno v:
Non-Coding RNA, Vol 7, Iss 1, p 1 (2020)
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy in adults. Although significant progress has been made in recent years to treat DLBCL patients, 30%–40% of the patients eventually relapse or are refractory to first line
Externí odkaz:
https://doaj.org/article/45ded4266a314572ac2484301bd5dc60
Autor:
Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, Sara Terreri, Eric Wang, Frances A. Collins, Lauren A. Woodward, Allison E. Walker, Deedra Nicolet, Felice Pepe, Prasanthi Kumchala, Marius Bill, Christopher J. Walker, Malith Karunasiri, Krzysztof Mrózek, Miranda L. Gardner, Virginia Camilotto, Nina Zitzer, Jonathan L. Cooper, Xiongwei Cai, Xiaoqing Rong-Mullins, Jessica Kohlschmidt, Kellie J. Archer, Michael A. Freitas, Yi Zheng, Robert J. Lee, Iannis Aifantis, George Vassiliou, Guramrit Singh, Sakari Kauppinen, Clara D. Bloomfield, Adrienne M. Dorrance, Ramiro Garzon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/99c4ed0bb3fa44d68071a84f1b74e8bd
Autor:
Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, Sara Terreri, Eric Wang, Frances A. Collins, Lauren A. Woodward, Allison E. Walker, Deedra Nicolet, Felice Pepe, Prasanthi Kumchala, Marius Bill, Christopher J. Walker, Malith Karunasiri, Krzysztof Mrózek, Miranda L. Gardner, Virginia Camilotto, Nina Zitzer, Jonathan L. Cooper, Xiongwei Cai, Xiaoqing Rong-Mullins, Jessica Kohlschmidt, Kellie J. Archer, Michael A. Freitas, Yi Zheng, Robert J. Lee, Iannis Aifantis, George Vassiliou, Guramrit Singh, Sakari Kauppinen, Clara D. Bloomfield, Adrienne M. Dorrance, Ramiro Garzon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/579218a2e8fe43ea90c3edcd2d6f65f6
Autor:
Andreas Petri, Karen Dybkær, Martin Bøgsted, Charlotte Albæk Thrue, Peter H Hagedorn, Alexander Schmitz, Julie Støve Bødker, Hans Erik Johnsen, Sakari Kauppinen
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138236 (2015)
Long noncoding RNAs (lncRNAs) have emerged as important regulators of diverse cellular processes, but their roles in the developing immune system are poorly understood. In this study, we analysed lncRNA expression during human B-cell development by a
Externí odkaz:
https://doaj.org/article/574c8064bfa940cab43b3627e501bf60
Autor:
Josine L Min, George Nicholson, Ingileif Halgrimsdottir, Kristian Almstrup, Andreas Petri, Amy Barrett, Mary Travers, Nigel W Rayner, Reedik Mägi, Fredrik H Pettersson, John Broxholme, Matt J Neville, Quin F Wills, Jane Cheeseman, GIANT Consortium, MolPAGE Consortium, Maxine Allen, Chris C Holmes, Tim D Spector, Jan Fleckner, Mark I McCarthy, Fredrik Karpe, Cecilia M Lindgren, Krina T Zondervan
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002505 (2012)
Metabolic Syndrome (MetS) is highly prevalent and has considerable public health impact, but its underlying genetic factors remain elusive. To identify gene networks involved in MetS, we conducted whole-genome expression and genotype profiling on abd
Externí odkaz:
https://doaj.org/article/48c00fdd38354c18b5237e49bea1cf97
Autor:
Marianne Bengtson Løvendorf, Anja Holm, Andreas Petri, Charlotte Albæk Thrue, Shizuka Uchida, Morten T. Venø, Sakari Kauppinen
Publikováno v:
Løvendorf, M B, Holm, A, Petri, A, Thrue, C A, Uchida, S, Venø, M T & Kauppinen, S 2023, ' Knockdown of Circular RNAs Using LNA-Modified Antisense Oligonucleotides ', Nucleic Acid Therapeutics, vol. 33, no. 1, pp. 45-57 . https://doi.org/10.1089/nat.2022.0040
Circular RNAs (circRNAs) constitute an abundant class of covalently closed noncoding RNA molecules that are formed by backsplicing from eukaryotic protein-coding genes. Recent studies have shown that circRNAs can act as microRNA or protein decoys, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf56af7bae4a63e959a05eb44a9a8180
https://vbn.aau.dk/da/publications/c8ac8abb-41c5-4267-92e9-2d6f6fc47b46
https://vbn.aau.dk/da/publications/c8ac8abb-41c5-4267-92e9-2d6f6fc47b46