Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Andreas Pavlou"'
Autor:
Olivia Luise Gern, Andreas Pavlou, Felix Mulenge, Lena Mareike Busker, Luca Ghita, Angela Aringo, Bibiana Costa, Julia Spanier, Inken Waltl, Martin Stangel, Ulrich Kalinke
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Viral encephalitis is characterized by a series of immunological reactions that can control virus infection in the brain, but dysregulated responses may cause excessive inflammation and brain damage. Microglia are brain-resident myeloid cell
Externí odkaz:
https://doaj.org/article/3a4b81cf883c496bbc455a39ca77bc0f
Autor:
Felix Mulenge, Olivia Luise Gern, Lena Mareike Busker, Angela Aringo, Luca Ghita, Inken Waltl, Andreas Pavlou, Ulrich Kalinke
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Microglia serve as a front-line defense against neuroinvasive viral infection, however, determination of their actual transcriptional profiles under conditions of health and disease is challenging. Here, we used various experimental approach
Externí odkaz:
https://doaj.org/article/42bbe73b5ce7422b97270cafad9590e0
Autor:
Bibiana Costa, Jennifer Becker, Tobias Krammer, Felix Mulenge, Verónica Durán, Andreas Pavlou, Olivia Luise Gern, Xiaojing Chu, Yang Li, Luka Čičin-Šain, Britta Eiz-Vesper, Martin Messerle, Lars Dölken, Antoine-Emmanuel Saliba, Florian Erhard, Ulrich Kalinke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Human cytomegalovirus (HCMV) is a widespread pathogen that in immunocompromised hosts can cause life-threatening disease. Studying HCMV-exposed monocyte-derived dendritic cells by single-cell RNA sequencing, we observe that most cells are en
Externí odkaz:
https://doaj.org/article/7e57f2fc99c0427a90c6d097bb173ff7
Autor:
Melanie Bühler, Dandan Li, Lin Li, Sandra Runft, Inken Waltl, Andreas Pavlou, Ulrich Kalinke, Malgorzata Ciurkiewicz, Jochen Huehn, Stefan Floess, Andreas Beineke, Wolfgang Baumgärtner, Ingo Gerhauser
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Theiler’s murine encephalomyelitis virus (TMEV) is a single-stranded RNA virus that causes encephalitis followed by chronic demyelination in SJL mice and spontaneous seizures in C57BL/6 mice. Since earlier studies indicated a cr
Externí odkaz:
https://doaj.org/article/e30bc8fc773a48b2ba2840f704b52b59
Autor:
Lukas Mathias Michaely, Lukas Schuwerk, Lisa Allnoch, Kathleen Schön, Inken Waltl, Pia-Katharina Larsen, Andreas Pavlou, Chittappen Kandiyil Prajeeth, Guus F. Rimmelzwaan, Stefanie C. Becker, Ulrich Kalinke, Wolfgang Baumgärtner, Ingo Gerhauser
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12492 (2022)
Rift Valley fever (RVF) is a zoonotic and emerging disease, caused by the RVF virus (RVFV). In ruminants, it leads to “abortion storms” and enhanced mortality rates in young animals, whereas in humans it can cause symptoms like severe hemorrhagic
Externí odkaz:
https://doaj.org/article/5867e0979d2f4e39ad3537cffa4e994e
Autor:
Olivia Luise Gern, Felix Mulenge, Andreas Pavlou, Luca Ghita, Imke Steffen, Martin Stangel, Ulrich Kalinke
Publikováno v:
Viruses, Vol 13, Iss 10, p 2065 (2021)
Viral encephalitis is a rare but serious syndrome. In addition to DNA-encoded herpes viruses, such as herpes simplex virus and varicella zoster virus, RNA-encoded viruses from the families of Flaviviridae, Rhabdoviridae and Paramyxoviridae are import
Externí odkaz:
https://doaj.org/article/d35e9c3211304d50b254be3210cfa77f
Autor:
Matthias Bruhn, Maureen Obara, Abhishek Chiyyeadu, Bibiana Costa, Abdus Salam, Annett Ziegler, Inken Waltl, Andreas Pavlou, Agnes Bonifacius, Markus Hoffmann, Theresa Graalmann, Stefan Pöhlmann, Britta Eiz-Vesper, Axel Schambach, Ulrich Kalinke
During the COVID-19 pandemic, numerous new SARS-CoV-2 variants of concern (VOC) evolved, many of which escape from antibody responses. Vaccination of COVID-19 convalescent individuals induces antibody responses of superior quantity and quality, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51872e006e9998f4063a90c89d07f9f3
https://doi.org/10.21203/rs.3.rs-2733470/v1
https://doi.org/10.21203/rs.3.rs-2733470/v1
Autor:
Jessica Kronenberg, Kaweh Pars, Marina Brieskorn, Chittappen K. Prajeeth, Sandra Heckers, Philipp Schwenkenbecher, Thomas Skripuletz, Refik Pul, Andreas Pavlou, Martin Stangel
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 2, p 325 (2019)
Dimethylfumarate (DMF) has been approved the for treatment of relapsing-remitting multiple sclerosis. The mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood, notably for brain reside
Externí odkaz:
https://doaj.org/article/ecf294d1a28c403da7c6c6896419544a
Autor:
Bibiana Costa, Jennifer Becker, Tobias Krammer, Felix Mulenge, Verónica Durán, Andreas Pavlou, Xiaojing Chu, Yang Li, Luka Cicin-Sain, Britta Eiz-Vesper, Lars Dolken, Antoine-Emmanuel Saliba, Florian Erhard, Ulrich Kalinke
Human cytomegalovirus (HCMV) is a widespread obligatory human pathogen causing life-threatening disease in immunocompromised hosts. Myeloid cells such as monocyte-derived dendritic cells (moDCs) are targets of HCMV. Here, we performed single-cell RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f1db64be7eef172a6eba683b8c47dba
https://doi.org/10.21203/rs.3.rs-953016/v1
https://doi.org/10.21203/rs.3.rs-953016/v1
Publikováno v:
Metabolism and Target Organ Damage. 3:6
Prevention of cardiovascular disease (CVD) is one of the main objectives in the management of people with type 2 diabetes (T2DM). New glucose-lowering therapies such as glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotranspo