Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andreas Panopoulos"'
Autor:
Michael Howell, Robert L. Margolis, Justin J Choi, Arun Fotedar, Howard Brickner, Céline DerMardirossian, Andreas Panopoulos, Daniel Miller, Rati Fotedar, Jean-Michel Saffin, Violaine D. Delorme-Walker
Publikováno v:
The Journal of Cell Biology
WISp39 associates with Hsp90, Coronin 1B, and Slingshot phosphatase to regulate Cofilin activation and Arp2/3 complex localization at the leading edge of migrating cells.
We previously identified Waf1 Cip1 stabilizing protein 39 (WISp39) as a bi
We previously identified Waf1 Cip1 stabilizing protein 39 (WISp39) as a bi
Autor:
Mark A. Sussman, Cristina Pacios-Bras, Andreas Panopoulos, Robert L. Margolis, Mythili Yenjerla, Justin J Choi, Rati Fotedar
Publikováno v:
Molecular Biology of the Cell
Induction of tetraploidy through cleavage failure induces G1 arrest and senescence in primary mammalian cells but not in immortal cells. Induction of senescence occurs without DNA damage, and the capacity to become senescent appears to be a prerequis
Autor:
Samar Alzeer, Gail McGarvie, Stuart M. Johnston, Andreas Panopoulos, Elizabeth M. Ellis, Robert C. Lyon
Publikováno v:
Chemico-Biological Interactions. 178:283-287
The metabolism of the endogenous metabolite gamma-hydroxybutyrate (GHB) has been studied in a human neuroblastoma cell line SH-SY5Y as a model for examining neuronal metabolism. We show that GHB can be synthesized and released from these cells, indic
Autor:
Françoise B. Lacroix, Dimitrios A. Skoufias, Rose-Laure Indorato, Robert L. Margolis, Andreas Panopoulos
Publikováno v:
The Journal of Cell Biology
Cellular transition to anaphase and mitotic exit has been linked to the loss of cyclin-dependent kinase 1 (Cdk1) kinase activity as a result of anaphase-promoting complex/cyclosome (APC/C)–dependent specific degradation of its cyclin B1 subunit. Cd
Publikováno v:
Journal of Biological Chemistry. 280:2912-2923
Coordinated and specific regulation of tumor necrosis factor (TNF) and interleukin (IL)-1 signaling pathways and how and whether they are modified by different agents are key events for proper immune responses. The IkappaB kinase complex (IKK)/NF-kap
Publikováno v:
Cell Cycle
Cell Cycle, Taylor & Francis, 2014, 12 (5), pp.837-841. ⟨10.4161/cc.23821⟩
Cell Cycle, Taylor & Francis, 2014, 12 (5), pp.837-841. ⟨10.4161/cc.23821⟩
International audience; We previously identified TD-60 (RCC2) as a mitotic centromere-associated protein that is necessary for proper completion of mitosis. We now report that TD-60 is an essential regulator of cell cycle progression during interphas
Publikováno v:
Molecular Biology of the Cell
Human glioblastoma cells are motile in the absence of intact actin polymers, following suppression of actin assembly by specific inhibitors. On the other hand, suppression of microtubules completely blocks motility. These results are clearly divergen
Publikováno v:
Cytokine. 34(1-2)
A role for pro-inflammatory cytokines in inflammation-related cancers has been suggested, but mechanisms are not defined. Here, we demonstrate that treatment of HeLa cells with TNFalpha increases chromosomal aberration. In contrast, IL-1beta did not
Autor:
Cheng-Ho Chung, Robert L. Margolis, Alexey V. Terskikh, Ergeng Hao, Andreas Panopoulos, Amber Miller, Fred Levine
Publikováno v:
Physiological Reports
The maternal embryonic leucine zipper kinase (MELK) is expressed in stem/progenitor cells in some adult tissues, where it has been implicated in diverse biological processes, including the control of cell proliferation. Here, we described studies on