Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andreas P. Sutter"'
Autor:
Detlef Schuppan, Michael Höpfner, Viola Baradari, Alexander Huether, Andreas P. Sutter, Hans Scherübl
Publikováno v:
Biochemical Pharmacology. 71:1435-1448
Hepatocellular carcinoma (HCC) is one of the most common cancer-related causes of death worldwide. Due to very poor 5-year-survival new therapeutic approaches are mandatory. Most HCCs express insulin-like growth factors and their receptors (IGF-R). A
Autor:
Kerstin Maaser, Andreas P. Sutter, Detlef Schuppan, Michael Höpfner, Hans Scherübl, Alexander Huether
Publikováno v:
Journal of Hepatology. 43:808-816
Background/Aims Hepatocellular carcinoma (HCC) is the fifth most common cause of cancer deaths worldwide. Inhibitors of cholesterol biosynthesis (‘statins') have been proposed as promising adjunctive anticancer agents to treat HCC, but their mode o
Autor:
Andreas P. Sutter, Martin Zeitz, Michael Höpfner, Hans Scherübl, Detlef Schuppan, Alexander Huether
Publikováno v:
Journal of Hepatology. 41:1008-1016
Background/Aims Hepatocellular carcinoma (HCC) is one of the most common cancer-related causes of death worldwide. Due to very poor 5-year-survival new therapeutic approaches are mandatory. Gefitinib, an inhibitor of epidermal growth factor receptor
Autor:
Rajan Somasundaram, Michael Höpfner, Detlef Schuppan, Bernhard Heine, Kerstin Maaser, Harald Stein, Martin Zeitz, Antje Krahn, Gesine Bradacs, Hans Scherübl, Kirsten Vormbrock, Patricia Grabowski, Andreas P. Sutter
Publikováno v:
Journal of Hepatology. 41:799-807
Background/Aims Hepatocellular carcinoma (HCC) is one of the most common causes of cancer deaths worldwide. Thus, novel therapies are urgently needed. A promising approach is the use of peripheral benzodiazepine receptor (PBR) ligands which inhibit t
Autor:
Patricia Grabowski, Andreas P. Sutter, Antje Krahn, Hans Scherübl, Michael Höpfner, Kerstin Maaser
Publikováno v:
Biochemical and Biophysical Research Communications. 324:878-886
Specific ligands of the peripheral benzodiazepine receptor (PBR) have been shown to induce both apoptosis and G1/G0 cell cycle arrest in colorectal cancers. The signaling pathways leading to cell cycle arrest are still unknown. Using cDNA array techn
Publikováno v:
World journal of gastroenterology. 12(35)
AIM: To investigate the antineoplastic potency of the novel insulin-like growth factor 1 receptor (IGF-1R) tyrosine kinase inhibitor (TKI) NVP-AEW541 in cell lines and primary cell cultures of human colorectal cancer (CRC). METHODS: Cells of primary
Autor:
Alexander, Huether, Michael, Hopfner, Andreas P, Sutter, Viola, Baradari, Detlef, Schuppan, Hans, Scherubl
Publikováno v:
World journal of gastroenterology. 12(32)
To examine the underlying mechanisms of erlotinib-induced growth inhibition in hepatocellular carcinoma (HCC).Erlotinib-induced alterations in gene expression were evaluated using cDNA array technology; changes in protein expression and/or protein ac
Publikováno v:
Molekulare Medizin ISBN: 3540287817
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab9da6bc9c75b7c76189722cbc95189e
https://doi.org/10.1007/3-540-28782-5_12
https://doi.org/10.1007/3-540-28782-5_12
Publikováno v:
Biochemical and biophysical research communications. 332(3)
Specific ligands of the peripheral benzodiazepine receptor (PBR) have been shown to induce apoptosis in gastrointestinal cancers. The aim of this study was to characterize the signaling pathways of PBR ligand-induced apoptosis. FGIN-1-27 but not PK 1
Publikováno v:
Journal of hepatology. 43(4)
Background/Aims Hepatocellular carcinoma (HCC) is one of the most common cancer-related causes of death worldwide. In light of the very poor 5-year-survival new therapeutic approaches are urgently needed. Recently, evidence has been accumulated that