Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andreas O Stucki"'
Autor:
Arunima Sengupta, Aurélien Dorn, Mohammad Jamshidi, Magali Schwob, Widad Hassan, Lea Lara De Maddalena, Andreas Hugi, Andreas O. Stucki, Patrick Dorn, Thomas M. Marti, Oliver Wisser, Janick D. Stucki, Tobias Krebs, Nina Hobi, Olivier T. Guenat
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Prolonged exposure to environmental respirable toxicants can lead to the development and worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD) and fibrosis. The limited number of FDA-approved inhaled dr
Externí odkaz:
https://doaj.org/article/c791da18c4f74563afefe4f78478af93
Autor:
Andreas O. Stucki, Amy J. Clippinger, Tala R. Henry, Carole Hirn, Todd J. Stedeford, Claire Terry
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Externí odkaz:
https://doaj.org/article/a0cd755f8df1408ab40a9496c3f0a4bc
Autor:
Andreas O. Stucki, Tara S. Barton-Maclaren, Yadvinder Bhuller, Joseph E. Henriquez, Tala R. Henry, Carole Hirn, Jacqueline Miller-Holt, Edith G. Nagy, Monique M. Perron, Deborah E. Ratzlaff, Todd J. Stedeford, Amy J. Clippinger
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
New approach methodologies (NAMs) are increasingly being used for regulatory decision making by agencies worldwide because of their potential to reliably and efficiently produce information that is fit for purpose while reducing animal use. This arti
Externí odkaz:
https://doaj.org/article/91f5086d950c401f962ceec188486c27
Autor:
Jacqueline Miller-Holt, Holger P. Behrsing, Amy J. Clippinger, Carole Hirn, Todd J. Stedeford, Andreas O. Stucki
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Regulatory frameworks on tobacco and other nicotine-containing products (TNCP) continue to evolve as novel products emerge, including electronic nicotine delivery systems (e.g., electronic cigarettes or vaping products), heated tobacco products, or c
Externí odkaz:
https://doaj.org/article/9b05286bedab4fa19a357623477dbd22
Autor:
Kyeonghee Monica Lee, Richard Corley, Annie M. Jarabek, Nicole Kleinstreuer, Alicia Paini, Andreas O. Stucki, Shannon Bell
Publikováno v:
Toxics, Vol 10, Iss 12, p 760 (2022)
New approach methodologies (NAMs) are emerging chemical safety assessment tools consisting of in vitro and in silico (computational) methodologies intended to reduce, refine, or replace (3R) various in vivo animal testing methods traditionally used f
Externí odkaz:
https://doaj.org/article/3b6b58359df3489993c72a96cf9e262e
Autor:
Vivek S Patel, Khalid Amin, Adam Wahab, Méry Marimoutou, Lindsey Ukishima, Jose Alvarez, Kelley Battle, Andreas O Stucki, Amy J Clippinger, Holger P Behrsing
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology.
Human precision-cut lung slices (hPCLS), considered a highly relevant ex vivo model of the lung, offer native architecture and cells of the lung tissue including respiratory parenchyma, small airways, and immune competent cells. However, the irregula
Autor:
Elijah J. Petersen, Andreas Luch, Aaron Katz, Lars Leibrock, Monita Sharma, Peter Laux, John Gordon, Amy J. Clippinger, Frank S. Bierkandt, Jutta Tentschert, Andreas O. Stucki, Joanna Matheson
Publikováno v:
Chemical Research in Toxicology. 34:1370-1385
In vitro inhalation toxicology methods are increasingly being used for research and regulatory purposes. Although the opportunity for increased human relevance of in vitro inhalation methods compared to in vivo tests has been established and discusse
Autor:
Aline Chary, Katherine Groff, Andreas O. Stucki, Servane Contal, Charlotte Stoffels, Sébastien Cambier, Monita Sharma, Arno C. Gutleb, Amy J. Clippinger
Publikováno v:
Toxicology in Vitro. 83:105423
Scientists are using in vitro methods to answer important research questions and implementing strategies to maximize the reliability and human relevance of these methods. One strategy is to replace the use of fetal bovine serum (FBS)-an undefined and