Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Andreas Niederquell"'
Publikováno v:
Journal of Pharmaceutical Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b174c0338cf5b755fbed285d40bad06
https://doi.org/10.1016/j.xphs.2023.02.013
https://doi.org/10.1016/j.xphs.2023.02.013
Publikováno v:
Molecular pharmaceutics. 19(2)
There has been recent interest in using hydroxypropyl cellulose (HPC) for supersaturating drug formulations. This study investigated the potential for molecular HPC interactions with the model drug celecoxib by integrating novel approaches in the fie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01582b997e98ca000f381d0a5b446f0c
https://pubmed.ncbi.nlm.nih.gov/35005970
https://pubmed.ncbi.nlm.nih.gov/35005970
Autor:
Jana Brokešová, Andreas Niederquell, Martin Kuentz, Petr Zámostný, Barbora Vraníková, Zdenka Šklubalová
Publikováno v:
International Journal of Pharmaceutics. 631:122485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ec90f5d3f87ada5b6a838242c34c56
https://doi.org/10.1016/j.ijpharm.2022.122485
https://doi.org/10.1016/j.ijpharm.2022.122485
Autor:
Jana, Brokešová, Andreas, Niederquell, Martin, Kuentz, Petr, Zámostný, Barbora, Vraníková, Zdenka, Šklubalová
Publikováno v:
International Journal of Pharmaceutics. 626:122198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d2a08e76773ac738a4c855f20b1d20
https://doi.org/10.1016/j.ijpharm.2022.122198
https://doi.org/10.1016/j.ijpharm.2022.122198
Publikováno v:
Journal of Pharmaceutical Sciences. 108:3457-3460
Drug solubility screening in solvents and lipids is central for the development of lipid-based formulations (LBFs), and any guidance to reduce the experimental workload would be highly desirable. Solubility parameters are interesting as they can be p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a002523812d0283fad94e35957240a
https://doi.org/10.1016/j.xphs.2019.06.014
https://doi.org/10.1016/j.xphs.2019.06.014
Publikováno v:
Molecular pharmaceutics. 17(7)
There has been much recent interest in machine learning (ML) and molecular quantitative structure property relationships (QSPR). The present research evaluated modern ML-based methods implemented in commercial software (COSMOquick and Molecular Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6c8f26b8a0ac013d1cc8b88ce8a8d0
https://pubmed.ncbi.nlm.nih.gov/32496787
https://pubmed.ncbi.nlm.nih.gov/32496787
Publikováno v:
International Journal of Pharmaceutics. 546:137-144
Solubility parameters have been applied extensively in the chemical and pharmaceutical sciences. Particularly attractive is calculation of solubility parameters based on chemical structure and recently, new in silico methods have been proposed. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3558d84d39d637292e16243c78cfaddc
https://doi.org/10.1016/j.ijpharm.2018.05.033
https://doi.org/10.1016/j.ijpharm.2018.05.033
Autor:
Andreas Niederquell, Martin Kuentz
Publikováno v:
Journal of Pharmaceutical Sciences. 107:503-506
It is for the pharmaceutical sciences of vital importance to understand how drugs are solubilized in biorelevant media. However, the complexity of fasted state simulated intestinal fluid (FaSSIF) has so far hampered adequate solubility modeling. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89957de5c8736882e654a61cc497686
https://doi.org/10.1016/j.xphs.2017.08.017
https://doi.org/10.1016/j.xphs.2017.08.017
Publikováno v:
International Journal of Pharmaceutics. 530:213-223
Emulsions are broadly used in pharmaceutics either as intermediate products or as final dosage forms. Such disperse systems are only kinetically stabilized and therefore early detection of physical instability is highly desirable. This work employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a459315f54ee3e1927f198d38a3766ef
https://doi.org/10.1016/j.ijpharm.2017.07.038
https://doi.org/10.1016/j.ijpharm.2017.07.038
Publikováno v:
International journal of pharmaceutics. 578
Despite the increasing interest in pharmaceutical use of mesoporous silica, there is still only limited knowledge on mechanisms of pore loading and subsequent drug desorption and release. Hence the aim of this work was to address the mechanistic aspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56295309e54d345bf8caac115b9d9272
https://pubmed.ncbi.nlm.nih.gov/32006624
https://pubmed.ncbi.nlm.nih.gov/32006624