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of 281
pro vyhledávání: '"Andreas Natsch"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1002-1007 (2021)
Benzyl salicylate (BS) is a natural ingredient of essential oils and a widely used fragrance chemical. A number of in vitro screening studies have evaluated the estrogenic potential of BS with ambiguous results. Lack of dose-response information for
Externí odkaz:
https://doaj.org/article/58546729d6e241fd997292d5c2249fb8
Publikováno v:
Archives of Toxicology. 97:1433-1437
The EU chemical strategy for sustainability (CSS) plans to use chemical grouping to “prioritise (…) substances for restrictions for all uses through grouping, instead of regulating them one by one”. Thus, toxicological grouping will become a ke
Autor:
Niamh M O’Boyle, Ida B Niklasson, David J Ponting, Miguel A Ortega, Tina Seifert, Andreas Natsch, Kristina Luthman, Ann-Therese Karlberg
Publikováno v:
Toxicology and Industrial Health. 38:259-269
We describe a novel nature-derived epoxy resin monomer (ERM) derived from the plant lignan pinoresinol. Epoxy resins are thermosetting materials in global usage owing to their excellent technical properties such as flexibility and durability. However
Autor:
Andreas Natsch
Publikováno v:
ALTEX.
Autor:
Andreas Natsch
Publikováno v:
Archives of Toxicology
The EU chemical strategy for sustainability places a high focus on endocrine-disrupting chemicals (ED), the importance of their identification with increased testing and a ban in consumer products by a generic approach. It is assumed that for ED no t
Publikováno v:
Applied In Vitro Toxicology. 7:102-111
Introduction: Prediction models of most toxicological assays translate continuous data to binary classifications (“positive” or “negative”) using cutoff values. Mostly these cutoffs do not consider...
Autor:
Lars Hareng, Paul Schuster, Volker Haake, Tilman Walk, Michael Herold, Heike Laue, Andreas Natsch
Publikováno v:
Archives of toxicology. 97(1)
Molecules metabolized to para-tert-butyl-benzoic acid (p-TBBA) affect male reproduction in rats through effects on spermatogenesis. This toxicity is specific to p-TBBA and not observed in meta-substituted analogues. The underlying mode of action was
Publikováno v:
Regulatory Toxicology and Pharmacology. 140:105371
Autor:
Lu Hostettler, Jon A. Arnot, Gordon Sanders, Andreas Natsch, Karen J. Jenner, Heike Laue, Remo P. Badertscher
Publikováno v:
Environmental Science & Technology. 54:9483-9494
In vitro biotransformation rates were determined for 30 chemicals, mostly fragrance ingredients, using trout liver S9 fractions (RT-S9) and incorporated into in vitro-in vivo extrapolation (IVIVE) models to predict bioconcentration factors (BCFs). Pr
Autor:
Yue Zou, Jie Liu, Sereina Riniker, Lijun Zhou, Stephanie M. Linker, Vera Hürlimann, Carmen Esposito, Roger Emter, Philip Kraft, Quanrui Wang, Andreas Natsch
Publikováno v:
Synlett. 31:972-976
A new family of dienone musks was discovered by alkylation of different aldehydes with but-3-en-1-yn-1-yllithium and subsequent domino reaction of a Saucy–Marbet transfer vinylation–Claisen rearrangement with an intramolecular Diels–Alder react