Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Andreas N. Madsen"'
Autor:
Christina Christoffersen, Christine K. Federspiel, Anna Borup, Pernille M. Christensen, Andreas N. Madsen, Markus Heine, Carsten H. Nielsen, Andreas Kjaer, Birgitte Holst, Joerg Heeren, Lars B. Nielsen
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 175-188 (2018)
Summary: Apolipoprotein M (apoM) is the carrier of sphingosine-1-phosphate (S1P) in plasma high-density lipoproteins. S1P is a bioactive lipid interacting with five receptors (S1P1–5). We show that lack of apoM in mice increases the amount of brown
Externí odkaz:
https://doaj.org/article/6bdab9afc9bb4f7496bbc7b2b6ee2500
Autor:
Karl Bacos, Luz Andreone, Kristian Helin, Aditya Sankar, Charlotte Ling, Madhusudhan Bysani, Thomas Mandrup-Poulsen, Marie Balslev Backe, Andreas N. Madsen, Birgitte Holst, Steen Seier Poulsen, Chunyu Jin, Marcelo Javier Perone, Karl Agger
Publikováno v:
Journal of Diabetes Research
Journal of Diabetes Research, Vol 2019 (2019)
Backe, M B, Jin, C, Andreone, L, Sankar, A, Agger, K, Helin, K, Madsen, A N, Poulsen, S S, Bysani, M, Bacos, K, Ling, C, Javier Perone, M, Holst, B & Mandrup-Poulsen, T 2019, ' The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis ', Journal of Diabetes Research, vol. 2019, 5451038 . https://doi.org/10.1155/2019/5451038
Journal of Diabetes Research, Vol 2019 (2019)
Backe, M B, Jin, C, Andreone, L, Sankar, A, Agger, K, Helin, K, Madsen, A N, Poulsen, S S, Bysani, M, Bacos, K, Ling, C, Javier Perone, M, Holst, B & Mandrup-Poulsen, T 2019, ' The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis ', Journal of Diabetes Research, vol. 2019, 5451038 . https://doi.org/10.1155/2019/5451038
Aims. Posttranslational modifications of histones and transcription factors regulate gene expression and are implicated in beta-cell failure and diabetes. We have recently shown that preserving H3K27 and H3K4 methylation using the lysine demethylase
Autor:
Thi Ai Diep, Andreas N Madsen, Sandra Krogh-Hansen, Marwa Al-Shahwani, Laila Al-Sabagh, Birgitte Holst, Harald S Hansen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100365 (2014)
BACKGROUND AND AIMS: Oleoylethanolamide and several other N-acylethanolamines (NAEs), e.g. linoleoylethanolamide and palmitoylethanolamide, have anorectic properties in rats, and prolonged intake of a high-fat diet decreases the levels of the anorect
Externí odkaz:
https://doaj.org/article/8f9e4fd7904f4211b62b1d8bf3f769f6
Autor:
Rashmi B. Prasad, Torben Hansen, Patrick C.N. Rensen, Sune Skeldal, Dorthe Maria Vittrup, Karen M. Pedersen, Olof Asplund, Christian Bjerggaard Vaegter, Anette Marianne Prior Gjessing, Andreas N. Madsen, Karen Marie Juul Sørensen, Mads Kjolby, Maarten Rotman, Dovile Januliene, Olav M. Andersen, Guido Hermey, Edwin T. Parlevliet, Birgitte Holst, Arne Moller, Gangadaar Thotakura, Ernst-Martin Füchtbauer, Søren Thirup, Peder Madsen, Niels Wellner, Peter Breining, Arulmani Manavalan
Type II diabetes mellitus (T2DM) has reached endemic levels and comprises a substantial burden to the patient and the society. Along with lifestyle factors, a number of genetic loci predisposing to T2DM have been suggested including SORCS1 that encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbdadf328d061149c37f06c00ea13f49
https://doi.org/10.1101/2020.11.10.376178
https://doi.org/10.1101/2020.11.10.376178
Autor:
Thue W. Schwartz, Maja S. Engelstoft, Andreas N. Madsen, Pascal Timshel, Jeppe P. Ekberg, Maria Hauge
Publikováno v:
Molecular and Cellular Endocrinology. 449:64-73
GPR40 is generally known to signal through Gq. However, in transfected cells, certain synthetic agonists can make the receptor signal also through Gs and cAMP (Hauge et al., 2015). Here we find that, in colonic crypt cultures, the GLP-1 secretion ind
Autor:
Birgitte Holst, Anna-Sofie Husted, Jeppe H. Ekberg, Thue W. Schwartz, Frank Reiman, Line Vildbrad Kristensen, Kristoffer L. Egerod, Fiona M. Gribble, Maja S. Engelstoft, Timothy J. Kowalski, Rasmus M. Sichlau, Harald S. Hansen, Andrew D. Howard, Andreas N. Madsen, Pascal Timshel, Maria Hauge
Publikováno v:
Endocrinology
Triglycerides (TGs) are among the most efficacious stimulators of incretin secretion; however, the relative importance of FFA1 (G Protein-coupled Receptor [GPR] 40), FFA4 (GPR120), and GPR119, which all recognize TG metabolites, ie, long-chain fatty
Autor:
Lis Hasholt, Birgitte Holst, Olga Rudenko, Andreas N. Madsen, Anne Nørremølle, Louisa J. Skov, Cecilie Springer
Publikováno v:
Journal of Neuroendocrinology. 31
Huntington's disease (HD) is a heritable neurodegenerative disorder, characterised by metabolic disturbances, along with cognitive and psychiatric impairments. Targeting metabolic HD dysfunction via the maintenance of body weight and fat mass and res
Autor:
Louise Aas Holm, Alireza Kashani, Birgitte Holst, Andreas N. Madsen, Georg K. Gerber, Asker Daniel Brejnrod, Timo Kern, Chunyu Jin, Manimozhiyan Arumugam, Torben Hansen, Jens-Christian Holm
Publikováno v:
Kashani, A, Brejnrod, A D, Jin, C, Kern, T, Madsen, A N, Holm, L A, Gerber, G K, Holm, J-C, Hansen, T, Holst, B & Arumugam, M 2019, ' Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice ', Animal Microbiome, vol. 1, 11 . https://doi.org/10.1186/s42523-019-0007-1
Animal Microbiome, Vol 1, Iss 1, Pp 1-16 (2019)
Animal Microbiome
Animal Microbiome, Vol 1, Iss 1, Pp 1-16 (2019)
Animal Microbiome
Background Growing evidence supports the role of gut microbiota in obesity and its related disorders including type 2 diabetes. Ob/ob mice, which are hyperphagic due to leptin deficiency, are commonly used models of obesity and were instrumental in s
Autor:
Annette G. Beck-Sickinger, Thue W. Schwartz, Kathrin Bellmann-Sickert, Helen M. Cox, Birgitte Holst, Andreas N. Madsen, V. Thieme, N. Jolly
Publikováno v:
British Journal of Pharmacology. 173:3208-3221
Background and purpose Human pancreatic polypeptide (hPP) is known to suppress appetite and food intake, thereby representing a potential therapeutic approach against obesity and associated metabolic disorders. The aim of this study was to improve hP
Autor:
Andreas N. Madsen, Aurelie Vandenbeuch, Anthony P. Thompson, Andrew A. Pieper, Martin D. Cassell, Lucas D. BonDurant, Terry C. Yin, Birgitte Holst, Adriana Ibarra Urizar, Cecilia Ratner, Thomas P. J. Solomon, Matthew P. Gillum, Sue C. Kinnamon, Catherine B. Anderson, Stephanie von Holstein-Rathlou, Kristin E. Claflin, Lila Peltekian, Meghan C. Naber, Matthew J. Potthoff, Kristian Karstoft, Kamal Rahmouni
Publikováno v:
Cell Metabolism. 23(2):335-343
Summary The liver is an important integrator of nutrient metabolism, yet no liver-derived factors regulating nutrient preference or carbohydrate appetite have been identified. Here we show that the liver regulates carbohydrate intake through producti