Short- and Long-Range Connections Differentially Modulate the Dynamics and State of Small-World Networks

Autor: Simon Arvin, Andreas Nørgaard Glud, Keisuke Yonehara

Publikováno v: Frontiers in Computational Neuroscience, Vol 15 (2022)

The human brain contains billions of neurons that flexibly interconnect to support local and global computational spans. As neuronal activity propagates through the neural medium, it approaches a critical state hedged between ordered and disordered s

Externí odkaz: https://doaj.org/article/6a4e9a73049344bc89983793c111386e

Anterograde Tracing From the Göttingen Minipig Motor and Prefrontal Cortex Displays a Topographic Subthalamic and Striatal Axonal Termination Pattern Comparable to Previous Findings in Primates

Autor: Johannes Bech Steinmüller, Carsten Reidies Bjarkam, Dariusz Orlowski, Jens Christian Hedemann Sørensen, Andreas Nørgaard Glud

Publikováno v: Frontiers in Neural Circuits, Vol 15 (2021)

Background: Deep brain stimulation (DBS) of the dorsal subthalamic nucleus (STN) is a validated neurosurgical treatment of Parkinson’s Disease (PD). To investigate the mechanism of action, including potential DBS induced neuroplasticity, we have pr

Externí odkaz: https://doaj.org/article/53e9f92bfc2742bf82b5c2697e3870b7

An Intracortical Implantable Brain-Computer Interface for Telemetric Real-Time Recording and Manipulation of Neuronal Circuits for Closed-Loop Intervention

Autor: Hamed Zaer, Ashlesha Deshmukh, Dariusz Orlowski, Wei Fan, Pierre-Hugues Prouvot, Andreas Nørgaard Glud, Morten Bjørn Jensen, Esben Schjødt Worm, Slávka Lukacova, Trine Werenberg Mikkelsen, Lise Moberg Fitting, John R. Adler, M. Bret Schneider, Martin Snejbjerg Jensen, Quanhai Fu, Vinson Go, James Morizio, Jens Christian Hedemann Sørensen, Albrecht Stroh

Publikováno v: Frontiers in Human Neuroscience, Vol 15 (2021)

Recording and manipulating neuronal ensemble activity is a key requirement in advanced neuromodulatory and behavior studies. Devices capable of both recording and manipulating neuronal activity brain-computer interfaces (BCIs) should ideally operate

Externí odkaz: https://doaj.org/article/556fdb6ef6c54a9bae6c12ed1c83e8af

Interventions to improve gait in Parkinson’s disease: a systematic review of randomized controlled trials and network meta-analysis

Autor: Victor Schwartz Hvingelby, Andreas Nørgaard Glud, Jens Christian Hedemann Sørensen, Yen Tai, Anne Sofie Møller Andersen, Erik Johnsen, Elena Moro, Nicola Pavese

Publikováno v: Hvingelby, V S, Glud, A N, Sørensen, J C H, Tai, Y, Andersen, A S M, Johnsen, E, Moro, E & Pavese, N 2022, ' Interventions to improve gait in Parkinson's disease : a systematic review of randomized controlled trials and network meta-analysis ', Journal of Neurology, vol. 269, no. 8, pp. 4068–4079 . https://doi.org/10.1007/s00415-022-11091-1

INTRODUCTION: Disabling gait symptoms, especially freezing of gait (FoG), represents a milestone in the progression of Parkinson's disease (PD). This systematic review and network meta-analysis assessed and ranked interventions according to their eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f416ddcb45f294b380a148ee1dc8cf2f
https://doi.org/10.1007/s00415-022-11091-1

Spinal cord stimulation therapy for patients with Parkinson's disease and gait problems (STEP-PD):study protocol for an exploratory, double-blind, randomised, placebo-controlled feasibility trial

Autor: Victor S Hvingelby, Miriam Højholt Terkelsen, Erik L Johnsen, Mette Møller, Erik Hvid Danielsen, Tove Henriksen, Andreas Nørgaard Glud, Yen Tai, Anne Sofie Møller Andersen, Kaare Meier, Per Borghammer, Elena Moro, Jens Christian Hedemann Sørensen, Nicola Pavese

Publikováno v: Hvingelby, V S, Højholt Terkelsen, M, Johnsen, E L, Møller, M, Danielsen, E H, Henriksen, T, Glud, A N, Tai, Y, Møller Andersen, A S, Meier, K, Borghammer, P, Moro, E, Sørensen, J C H & Pavese, N 2022, ' Spinal cord stimulation therapy for patients with Parkinson's disease and gait problems (STEP-PD) : study protocol for an exploratory, double-blind, randomised, placebo-controlled feasibility trial ', BMJ Neurology Open, vol. 4, no. 2, e000333 . https://doi.org/10.1136/bmjno-2022-000333
e000333

IntroductionGait difficulties are common in Parkinson’s disease (PD) and cause significant disability. These symptoms are often resistant to treatment. Spinal cord stimulation (SCS) has been found to improve gait, including freezing of gait, in a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64840889e9f2181a2c34ecbd2cc0d0b
https://pure.au.dk/portal/da/publications/spinal-cord-stimulation-therapy-for-patients-with-parkinsons-disease-and-gait-problems-steppd(d857db37-e386-4fcb-b7d8-7d1a2c9f914e).html