Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andreas Lodberg"'
Autor:
Mikkel Bo Brent, Frederik Duch, Andreas Lodberg, Ulf Simonsen, Bram C.J. van der Eerden, Jesper Skovhus Thomsen, Annemarie Brüel
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100322- (2020)
Externí odkaz:
https://doaj.org/article/eb990f7da69240ccb03e0be450ffe04c
Autor:
Francesco Maria Iena, Johanne Blanner Jul, Jens Bay Vegger, Andreas Lodberg, Jesper Skovhus Thomsen, Annemarie Brüel, Janne Lebeck
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Obesity is associated with increased plasma glycerol levels. The coordinated regulation of glycerol channels in adipose tissue (AQP7) and the liver (AQP9) has been suggested as an important contributor to the pathophysiology of type-2-diabetes mellit
Externí odkaz:
https://doaj.org/article/572d96c711e642e3bc8b54dc36ae0de7
Publikováno v:
MethodsX, Vol 7, Iss , Pp 101079- (2020)
Bone loss materializes rapidly after immobilization or mechanical unloading. Hind limb injection with botulinum toxin A (BTX) is a highly reproducible animal model for disuse-induced bone loss. Here we describe an easy-to-use and enhanced version of
Externí odkaz:
https://doaj.org/article/5271fe765d6142058c4549b1bde634f0
Autor:
Andreas Lodberg, Jens Bay Vegger, Michael Vinkel Jensen, Christian Mirian Larsen, Jesper Skovhus Thomsen, Annemarie Brüel
Publikováno v:
Bone Reports, Vol 2, Iss C, Pp 59-67 (2015)
Immobilization causes rapid and massive bone loss. By comparing Botulinum Toxin A (BTX)-induced bone loss in mouse strains with different genetic backgrounds we investigated whether the genetic background had an influence on the severity of the osteo
Externí odkaz:
https://doaj.org/article/dda07b3436a1435e929375b2cf8da6d4
Autor:
Andreas Lodberg
Publikováno v:
Lodberg, A 2021, ' Principles of the Activin Receptor Signaling Pathway and its Inhibition ', Cytokine & Growth Factor Reviews, vol. 60, pp. 1-17 . https://doi.org/10.1016/j.cytogfr.2021.04.001
This review captures the anabolic and stimulatory effects observed with inhibition of the transforming growth factor β superfamily in muscle, blood, and bone. New medicinal substances that rectify activin, myostatin, and growth differentiation facto
Autor:
Johannes P.T.M. van Leeuwen, Marco Eijken, Bram C. J. van der Eerden, Andreas Lodberg, Bianca Boers-Sijmons, Annemarie Brüel, Jesper Skovhus Thomsen
Publikováno v:
FASEB Journal, 33(5), 6001-6010. FASEB
Lodberg, A, van der Eerden, B C J, Boers-Sijmons, B, Thomsen, J S, Brüel, A, van Leeuwen, J P T M & Eijken, M 2019, ' A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice ', F A S E B Journal, vol. 33, no. 5, pp. 6001-6010 . https://doi.org/10.1096/fj.201801969RR
Lodberg, A, van der Eerden, B C J, Boers-Sijmons, B, Thomsen, J S, Brüel, A, van Leeuwen, J P T M & Eijken, M 2019, ' A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice ', F A S E B Journal, vol. 33, no. 5, pp. 6001-6010 . https://doi.org/10.1096/fj.201801969RR
Inhibitors of the activin receptor signaling pathway (IASPs) have become candidate therapeutics for sarcopenia and bone remodeling disorders because of their ability to increase muscle and bone mass. However, IASPs utilizing activin type IIA and IIB
Autor:
Janne Lebeck, Francesco Maria Iena, Jesper Skovhus Thomsen, Johanne Blanner Jul, Annemarie Brüel, Jens Bay Vegger, Andreas Lodberg
Publikováno v:
Frontiers in Endocrinology
Iena, F M, Jul, J B, Vegger, J B, Lodberg, A, Thomsen, J S, Brüel, A & Lebeck, J 2020, ' Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver ', Frontiers in Endocrinology, vol. 11, 577650 . https://doi.org/10.3389/fendo.2020.577650
Frontiers in Endocrinology, Vol 11 (2020)
Iena, F M, Jul, J B, Vegger, J B, Lodberg, A, Thomsen, J S, Brüel, A & Lebeck, J 2020, ' Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver ', Frontiers in Endocrinology, vol. 11, 577650 . https://doi.org/10.3389/fendo.2020.577650
Frontiers in Endocrinology, Vol 11 (2020)
Obesity is associated with increased plasma glycerol levels. The coordinated regulation of glycerol channels in adipose tissue (AQP7) and the liver (AQP9) has been suggested as an important contributor to the pathophysiology of type-2-diabetes mellit
Autor:
Annemarie Brüel, Bram C. J. van der Eerden, Frederik Duch, Mikkel Bo Brent, Ulf Simonsen, Andreas Lodberg, Jesper Skovhus Thomsen
Publikováno v:
Bone Reports, Vol 13, Iss, Pp 100322-(2020)
Autor:
Daniela Meier, Giovanni Pellegrini, Ana Gvozdenovic, Olga Neklyudova, Sander M. Botter, Marco Eijken, Bruno Fuchs, Walter Born, Andreas Lodberg
Publikováno v:
Cancer Medicine
Meier, D, Lodberg, A, Gvozdenovic, A, Pellegrini, G, Neklyudova, O, Born, W, Fuchs, B, Eijken, M & M Botter, S 2021, ' Inhibition of the activin receptor signaling pathway : A novel intervention against osteosarcoma ', Cancer Medicine, vol. 10, no. 1 . https://doi.org/10.1002/cam4.3581
Meier, D, Lodberg, A, Gvozdenovic, A, Pellegrini, G, Neklyudova, O, Born, W, Fuchs, B, Eijken, M & M Botter, S 2021, ' Inhibition of the activin receptor signaling pathway : A novel intervention against osteosarcoma ', Cancer Medicine, vol. 10, no. 1 . https://doi.org/10.1002/cam4.3581
Osteosarcoma is a cancer of pathological bone remodeling with high mortality and severe comorbidity. New therapies are urgently needed. Activin A, a member of the transforming growth factor β (TGFβ) superfamily, has been suggested to stimulate prol
Autor:
Frederik Duch Bromer, Marco Eijken, Bram C. J. van der Eerden, Jesper Skovhus Thomsen, Andreas Lodberg, Mikkel Bo Brent, Annemarie Brüel
Publikováno v:
Brent, M B, Lodberg, A, Bromer, F D, van der Eerden, B C J, Eijken, M, Brüel, A & Thomsen, J S 2021, ' Activin type IIA decoy receptor and intermittent parathyroid hormone in combination overturns the bone loss in disuse-osteopenic mice ', Bone, vol. 142, 115692 . https://doi.org/10.1016/j.bone.2020.115692
Bone, 142:115692. Elsevier Inc.
Bone, 142:115692. Elsevier Inc.
Damage of the lower motor neuron cell bodies or their axons results in reduced or abolished voluntary movement accompanied by a substantial loss of bone and muscle mass. Intermittent parathyroid hormone 1–34 (PTH) (teriparatide) is one of the most