Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andreas Leusch"'
Publikováno v:
Arzneimittelforschung. 51:947-954
The pharmacokinetics of 1-isoquinoline-acetamide, 3,4- dihydro- 6,7- dimethoxy- α - phenyl- N,N- bis [2- (2,3,4- trimethoxy-phenyl) ethyl]-, monomethanesulfonate (pinokalant, salt form of the active entity LOE 908 BS, CAS 143482-63-7), a nonselectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9aa14f0aafb27a7f40deccaede10d9
https://doi.org/10.1055/s-0031-1300143
https://doi.org/10.1055/s-0031-1300143
Altered drug disposition of the platelet activating factor antagonist apafant in mdr1a knockout mice
Autor:
Gabriele Müller, Astrid Volz, Willy Roth, Andrea Wagner, Achim Sauer, Andreas Greischel, Andreas Leusch
Publikováno v:
European Journal of Pharmaceutical Sciences. 16:119-128
The aim of the present study was to determine a potential impact of P-glycoprotein (P-gp) on the tissue distribution and disposition of apafant (WEB 2086, CAS 105219-56-5), a selective platelet-activating factor antagonist, and on digoxin in mdr1a(-/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6f6e647eff93b50092cfb7759b4732
https://doi.org/10.1016/s0928-0987(02)00088-x
https://doi.org/10.1016/s0928-0987(02)00088-x
Publikováno v:
Psychopharmacology. 162:292-300
Rationale. Muscarinic-acetylcholine receptor agonists are yet to be used clinically for the treatment of Alzheimer's disease (AD) even though laboratory evidence continues to support the potential for such an approach. Objectives. The purpose of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61efaabdb6f68d3debbb6be2249c988
https://doi.org/10.1007/s00213-002-1105-3
https://doi.org/10.1007/s00213-002-1105-3
Publikováno v:
Biopharmaceutics & Drug Disposition. 22:199-212
Ipratropium, a current treatment for chronic obstructive pulmonary disease (COPD) and tiotropium, a longer acting anticholinergic bronchodilator currently being developed for COPD are structurally related to atropine. In this study, the intravenous (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d1560eb8ceadc986fec6edf7948a72e
https://doi.org/10.1002/bdd.280
https://doi.org/10.1002/bdd.280
Publikováno v:
Xenobiotica. 30:797-814
1. Talsaclidine is an M1-agonist under development for the treatment of Alzheimer's disease. The aim of the study was to investigate the absorption, distribution, metabolism and excretion (ADME) of single intravenous and oral doses of [14C]-talsaclid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172fdcbe8a58fdc9707a2febd030887b
https://doi.org/10.1080/00498250050119853
https://doi.org/10.1080/00498250050119853
Autor:
Kathryn E. Saatman, Jessica A. Cheney, Ramesh Raghupathi, Adrienne L. Brown, Justin D. Weisser, Helmut Ensinger, Florence M. Bareyre, Andrew B. Russ, Andreas Leusch
Publikováno v:
Journal of Neurotrauma. 17:83-91
Experimental traumatic brain injury (TBI) initiates massive disturbances in Ca2+ concentrations in the brain that may contribute to neuronal damage. Intracellular Ca2+ may be elevated via influx through voltage-operated cation channels, ligand-gated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30d86a83258cc8f681dffee112160b1
https://doi.org/10.1089/neu.2000.17.83
https://doi.org/10.1089/neu.2000.17.83
Publikováno v:
Applied Biochemistry and Biotechnology. 61:231-249
Biosorption of cadmium (Cd), cobalt (Co), copper (Cu), nickel (Ni), lead (Pb), and zinc (Zn) by six fractions of particle sizes, ranging from 0.063 to 1.4 mm of dry marine algal biomass ofSargassum fluitans andAscophyllum nodosum, is examined. Equili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::554b2c2f802d1615baf11e12511d3c80
https://doi.org/10.1007/bf02787798
https://doi.org/10.1007/bf02787798
Autor:
Andreas Leusch, Bohumil Volesky
Publikováno v:
Journal of Biotechnology. 43:1-10
The sorption of cadmium by biomass of brown marine alga Sargassum fluitans has been studied in a standard mixed batch reactor at steady-state and transient conditions. Steady-state sorption data over the temperature range of 7 ° C to 60 ° C indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc9f30a14745e05e6df592027f8ddc3
https://doi.org/10.1016/0168-1656(95)00102-7
https://doi.org/10.1016/0168-1656(95)00102-7
Publikováno v:
Journal of Chemical Technology AND Biotechnology. 62:279-288
Particles of two different sizes (0·105–0·295 mm and 0·84–1.00 mm diameter) of two marine algae, Sargassum fluitans and Ascophyllum nodosum, were crosslinked with formaldehyde (FA), glutaraldehyde (GA) or embedded in polyethylene imine (PEI),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::745f84aa6e0e4a741220b233b84d9cb1
https://doi.org/10.1002/jctb.280620311
https://doi.org/10.1002/jctb.280620311
Publikováno v:
ChemInform. 25
The carboranyl amino acid 5-(2-methyl-1,2-dicarba-closo-dodecarborane(12)-1-yl)-2-aminopentanoic acid protected as the Boc derivative 1 has been used for the synthesis of peptides 2a-10 differing in chain length and boron content. Alternating the bul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5696b773aaa323861660da9b645f1265
https://doi.org/10.1002/chin.199436196
https://doi.org/10.1002/chin.199436196