Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andreas Krcal"'
Autor:
Andreas Krcal, Harald Eidherr, Verena Pichler, Tatjana Traub-Weidinger, Wolfgang Wadsak, Neydher Berroterán-Infante, Marcus Hacker, Chrysoula Vraka, Markus Mitterhauser
Publikováno v:
Applied Radiation and Isotopes. 141:107-111
Radiosynthetic optimization is crucial in routine PET production but is often neglected in literature. Small changes in the radiochemical procedure can increase the yield significantly and reduce time fluctuation within the synthetic procedure enabli
Autor:
Georg Dobrozemsky, Christoph Baumgartner, Markus Müller, Wolfgang Wadsak, Andreas Krcal, Rudolf Karch, Kurt Kletter, Ilka Steiner, Martin Brunner, Raute Sunder-Plassmann, Ulrich Müller, Oliver Langer, Christine Mannhalter, Robert Dudczak
Publikováno v:
Clinical Pharmacology & Therapeutics. 78:182-190
Background and Objective Single nucleotide polymorphisms in the human multidrug-resistance gene ABCB1 have been reported to be associated with altered expression and function of P-glycoprotein, an efflux transporter, expressed at the blood-brain barr
Autor:
Alexander Schmid, Diana Celona, Markus Müller, Andreas Krcal, Kurt Kletter, Aiman Abrahim, Oliver Langer, Dirk Roeda, Patrizia Minetti, Frédéric Dollé
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 48:577-587
1,1′-Methylene-di-(2-naphthol) (ST1859), a candidate drug for the treatment of Alzheimer's disease, was radiolabelled with carbon-11 with the aim to perform PET microdosing studies in humans. The radiosynthesis was automated in a commercial synthes
Autor:
Martin, Brunner, Oliver, Langer, Raute, Sunder-Plassmann, Georg, Dobrozemsky, Ulrich, Müller, Wolfgang, Wadsak, Andreas, Krcal, Rudolf, Karch, Christine, Mannhalter, Robert, Dudczak, Kurt, Kletter, Ilka, Steiner, Christoph, Baumgartner, Markus, Müller
Publikováno v:
Clinical pharmacology and therapeutics. 78(2)
Single nucleotide polymorphisms in the human multidrug-resistance gene ABCB1 have been reported to be associated with altered expression and function of P-glycoprotein, an efflux transporter, expressed at the blood-brain barrier. To test whether cert
Autor:
Joern Schmaljohann, Harald Eidherr, Wolfgang Wadsak, Andreas Krcal, Helmut Viernstein, Kurt Kletter, Robert Dudczak, Markus Mitterhauser, Alexander Schmid
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 62(3)
At present, most data available on PET imaging of brain tumors using amino acids are based on l-[S-methyl-11C]methionine (MET). This radiopharmaceutical accurately delineates tumor extent, sometimes even better than CT. Since MET is playing such an i
Autor:
Ewald Bartosch, Wolfgang Wadsak, Markus Mitterhauser, Harald Eidherr, Andreas Krcal, Helmut Viernstein, Kurt Kletter, Joern Schmaljohann
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 61(6)
[11C]Acetate, initially developed for nuclear cardiology has gained increased interest also for oncological problems. A conjoint problem of all preparation methods is the high sensitivity of the Grignard-precursor to moisture, demanding long cleaning
Autor:
Christian Pirich, Harald Eidherr, Wolfgang Wadsak, Robert Dudczak, Andreas Krcal, Helmut Viernstein, Kurt Kletter, Markus Mitterhauser
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 60(5)
Detection and follow up of bone metastases are important in diagnostic nuclear medicine. However, although the methods are well established, the mechanisms involved in the bone uptake of radiotracers still remain speculative. The aim of the present s