Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Andreas Kampkötter"'
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Akademický článek
Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16
Autor: Wim Wätjen, Andreas Kampkötter, Yvonni Chovolou, Gerhard Fritz, Sebastian Honnen, Daniela Ackermann, Susannah Havermann, Christian Büchter
Publikováno v: International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 11895-11914 (2013)
Myricetin is a naturally occurring flavonol found in many plant based food sources. It increases the lifespan of Caenorhabditis elegans, but the molecular mechanisms are not yet fully understood. We have investigated the impact of this flavonoid on t
Externí odkaz: https://doaj.org/article/81588c58f08244989f3485788decf6f5
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2
Akademický článek
C. elegans VANG-1 modulates life span via insulin/IGF-1-like signaling.
Autor: Sebastian J Honnen, Christian Büchter, Verena Schröder, Michael Hoffmann, Yuji Kohara, Andreas Kampkötter, Olaf Bossinger
Publikováno v: PLoS ONE, Vol 7, Iss 2, p e32183 (2012)
The planar cell polarity (PCP) pathway is highly conserved from Drosophila to humans and a PCP-like pathway has recently been described in the nematode Caenorhabditis elegans. The developmental function of this pathway is to coordinate the orientatio
Externí odkaz: https://doaj.org/article/231697696b8a4686b56993d7a3a7f556
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3
Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16
Autor: Susannah Havermann, Christian Büchter, Wim Wätjen, Daniela Ackermann, Yvonni Chovolou, Andreas Kampkötter, Gerhard Fritz, Sebastian Honnen
Publikováno v: International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 11895-11914 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 6; Pages: 11895-11914
Myricetin is a naturally occurring flavonol found in many plant based food sources. It increases the lifespan of Caenorhabditis elegans, but the molecular mechanisms are not yet fully understood. We have investigated the impact of this flavonoid on t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c03246c7b9919b9b1de4fff45606a7
http://www.mdpi.com/1422-0067/14/6/11895
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5
Hexa-, hepta- and nonaprenylhydroquinones isolated from marine sponges Sarcotragus muscarum and Ircinia fasciculata inhibit NF-k B signalling in H4IIE cells
Autor: Michael H.G. Kubbutat, Annika Putz, Yvonni Chovolou, Belma Konuklugil, Peter Proksch, Frank Totzke, Andreas Kampkötter, Wim Wätjen
Publikováno v: Journal of Pharmacy and Pharmacology. 61:919-924
Objectives Marine organisms have proven to be a rich source of potent pharmacologically active compounds. Three polyprenyl-1,4-hydroquinone derivates (hexaprenyl-1,4-hydroquinone, heptaprenyl-1,4-hydroquinone and nonaprenyl-1,4-hydroquinone) were iso
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c7ddd2e01eb9ee30facefb68a55e3ee
https://doi.org/10.1211/jpp.61.07.0011
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6
Enniatins A1, B and B1 from an endophytic strain ofFusarium tricinctuminduce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation
Autor: Frank Totzke, Andreas Kampkötter, Anke Hohlfeld, Rainer Ebel, Abdessamad Debbab, Yvonni Chovolou, Peter Proksch, A. Hakiki, Wim Wätjen, Mahjouba Mosaddak, Ru Angelie Edrada, Michael H.G. Kubbutat
Publikováno v: Molecular Nutrition & Food Research. 53:431-440
Enniatins are mycotoxins which have important impact on human health, e.g. as contaminants of cereals, but also are discussed as possible anticancer agents. We investigated toxic effects of enniatins A1, B and B1 isolated from Fusarium tricinctum on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880f1688f2f24dc7edf783edc343de55
https://doi.org/10.1002/mnfr.200700428
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7
Isoflavone daidzein possesses no antioxidant activities in cell-free assays but induces the antioxidant enzyme catalase
Autor: Yvonni Chovolou, Elke Röhrdanz, Nadine Weber, Peter Proksch, Andreas Kampkötter, Andreas Kulawik, Wim Wätjen
Publikováno v: Nutrition Research. 28:620-628
Epidemiologic studies have shown that dietary intake of isoflavonones is associated with several properties beneficial to human health. It has been suggested that at least some of these effects are related to the antioxidant activity of isoflavonoids
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f50394f8add6db726e993bf7ba9f7e
https://doi.org/10.1016/j.nutres.2008.06.002
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8
Catalase overexpression impairs TNF-α induced NF-κB activation and sensitizes MCF-7 cells against TNF-α
Autor: Yvonni Chovolou, Regine Lüpertz, Wim Wätjen, Andreas Kampkötter, Regine Kahl
Publikováno v: Journal of Cellular Biochemistry. 103:1497-1511
The pleiotropic cytokine tumor necrosis factor alpha (TNF-alpha) can induce apoptosis but also supports cell survival pathways. Among the possible anti-apoptotic mechanisms of TNF-alpha is the activation of the transcription factor NF-kappaB. Since r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd81da88166f6d0c7b9e7462ebee0826
https://doi.org/10.1002/jcb.21538
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9
Investigations of protective effects of the flavonoids quercetin and rutin on stress resistance in the model organism Caenorhabditis elegans
Autor: Andreas Kampkötter, Yvonni Chovolou, Wim Wätjen, Regine Kahl, Christiane Gombitang Nkwonkam, Claudia Timpel, Ruben Felix Zurawski
Publikováno v: Toxicology. 234:113-123
Oxidative stress as a result of excessive generation of reactive oxygen species (ROS) or diminished antioxidative defence is regarded as a main factor in the pathophysiology of various diseases and ageing. Many flavonoids that are present in herbal e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485439112510ecb381e5f1175baf8097
https://doi.org/10.1016/j.tox.2007.02.006
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10
Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells
Autor: Yvonni Chovolou, Nadine Weber, Peter Proksch, Wim Wätjen, Andreas Kampkötter, Regine Kahl, Yijia Lou, Zhiqiang Wang
Publikováno v: Food and Chemical Toxicology. 45:119-124
Antioxidative as well as cytotoxic effects of the prenylated flavonoids licoflavone C (8-prenylapigenin) and isobavachin (8-prenylliquiritigenin) were investigated in comparison to the corresponding non-prenylated flavonoids (apigenin, liquiritigenin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d34b13ad4ddbc1e77d621418f25982
https://doi.org/10.1016/j.fct.2006.08.008
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