Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andreas Ivessa"'
Autor:
Chun-yang Huang, Shin-ichi Oka, Xiaoyong Xu, Chian-Feng Chen, Chien-Yi Tung, Ya-Yuan Chang, Youssef Mourad, Omair Vehra, Andreas Ivessa, Ghassan Yehia, Peter Romanienko, Chiao-Po Hsu, Junichi Sadoshima
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract PERM1 (PGC-1/ERR-induced regulator in muscle 1) is a muscle-specific protein induced by PGC-1 and ERRs. Previous studies have shown that PERM1 promotes mitochondrial biogenesis and metabolism in cardiomyocytes in vitro. However, the role of
Externí odkaz:
https://doaj.org/article/7e77c979d53d4293a3e34436456b15e9
Autor:
Mariko Aoyagi Keller, Chun-yang Huang, Andreas Ivessa, Sukhwinder Singh, Peter J. Romanienko, Michinari Nakamura
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106409- (2023)
Summary: BCL-2-like protein 1 (BCL2L1) is a key component of cell survival and death mechanisms. Its dysregulation and altered ratio of splicing variants associate with pathologies. However, isoform-specific loss-of-function analysis of BCL2L1 remain
Externí odkaz:
https://doaj.org/article/4aa4f8fb0b914793b9530458ea482ea0
Autor:
Jamie Francisco, Yu Zhang, Yasuki Nakada, Jae Im Jeong, Chun-Yang Huang, Andreas Ivessa, Shinichi Oka, Gopal J. Babu, Dominic P. Del Re
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Fibrosis is a hallmark of heart disease independent of etiology and is thought to contribute to impaired cardiac dysfunction and development of heart failure. However, the underlying mechanisms that regulate the differentiation of fibroblast
Externí odkaz:
https://doaj.org/article/b2840988f77d4ca4a9dc4722061f9f74
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005283 (2015)
Telomeres, the ends of linear eukaryotic chromosomes, have a specialized chromatin structure that provides a stable chromosomal terminus. In budding yeast Rap1 protein binds to telomeric TG repeat and negatively regulates telomere length. Here we sho
Externí odkaz:
https://doaj.org/article/2353f09660ad49a6aa447aea0a30fc6b
Autor:
Jihoon Nah, Akihiro Shirakabe, Risa Mukai, Peiyong Zhai, Eun Ah Sung, Andreas Ivessa, Wataru Mizushima, Yasuki Nakada, Toshiro Saito, Chengchen Hu, Yong Keun Jung, Junichi Sadoshima
Publikováno v:
Cardiovascular research. 118(12)
Aims Well-controlled mitochondrial homeostasis, including a mitochondria-specific form of autophagy (hereafter referred to as mitophagy), is essential for maintaining cardiac function. The molecular mechanism mediating mitophagy during pressure overl
Publikováno v:
Aging cell. 10(3)
Regulator of G-protein signaling (RGS) proteins contribute to G-protein signaling pathways as activators or repressors with GTPase-activating protein (GAP) activity. To characterize whether regulation of RGS proteins influences longevity in several s