Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Andreas Hecht"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Unrestrained transcriptional activity of β-CATENIN and its binding partner TCF7L2 frequently underlies colorectal tumor initiation and is considered an obligatory oncogenic driver throughout intestinal carcinogenesis. Yet, the TCF7L2 gene c
Externí odkaz:
https://doaj.org/article/7b75a3241d4c4249bfe07d00bbe10437
Autor:
Sabine Jägle, Hauke Busch, Vivien Freihen, Sven Beyes, Monika Schrempp, Melanie Boerries, Andreas Hecht
Publikováno v:
PLoS Genetics, Vol 13, Iss 11, p e1007109 (2017)
Phenotypic conversion of tumor cells through epithelial-mesenchymal transition (EMT) requires massive gene expression changes. How these are brought about is not clear. Here we examined the impact of the EMT master regulator SNAIL1 on the FOXA family
Externí odkaz:
https://doaj.org/article/fb92509a2f8b4cd9ae8d6d53d09f4bc9
Autor:
Susanne Elfert, Andreas Weise, Katja Bruser, Martin L Biniossek, Sabine Jägle, Niklas Senghaas, Andreas Hecht
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61867 (2013)
The members of the TCF/LEF family of DNA-binding proteins are components of diverse gene regulatory networks. As nuclear effectors of Wnt/β-catenin signaling they act as assembly platforms for multimeric transcription complexes that either repress o
Externí odkaz:
https://doaj.org/article/c6c36ceddda6437890b3ef55896c42a6
Autor:
Pablo Antón-García, Elham Bavafaye Haghighi, Katja Rose, Georg Vladimirov, Melanie Boerries, Andreas Hecht
Publikováno v:
Cancers; Volume 15; Issue 2; Pages: 558
Epithelial-mesenchymal transition (EMT) fosters cancer cell invasion and metastasis, the main cause of cancer-related mortality. Growing evidence that SNAIL and ZEB transcription factors, typically portrayed as master regulators of EMT, may be dispen
Unrestrained transcriptional activity of β-CATENIN and its binding partner TCF7L2 frequently underlies colorectal tumor initiation and is considered an obligatory oncogenic driver throughout intestinal carcinogenesis. Yet, theTCF7L2gene carries inac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45bc94d11ee4250e3b38e228d018e6ed
https://doi.org/10.1101/2022.12.05.519142
https://doi.org/10.1101/2022.12.05.519142
Publikováno v:
Scientific reports. 13(1)
Unrestrained transcriptional activity of β-CATENIN and its binding partner TCF7L2 frequently underlies colorectal tumor initiation and is considered an obligatory oncogenic driver throughout intestinal carcinogenesis. Yet, theTCF7L2gene carries inac
Autor:
Dirk Hachmeister, Andreas Hecht
Publikováno v:
Journal of Corporate Accounting & Finance. 32:139-144
Sound decision-making depends on an appropriate level of relevant information. This topic is on the agenda of international standard setters in order to increase the decision usefulness of financial disclosures for the addressees of corporate reporti
Autor:
Constanze Lamprecht, Andreas Hecht, Gilles Rauen, Melanie Boerries, Janna Wenzel, Katja Rose, Vivien Freihen, Elham Bavafaye Haghighi, Rebecca Kesselring
Publikováno v:
Oncogene
The transcription factor TCF7L2 is indispensable for intestinal tissue homeostasis where it transmits mitogenic Wnt/β-Catenin signals in stem and progenitor cells, from which intestinal tumors arise. Yet, TCF7L2 belongs to the most frequently mutate
Autor:
Andreas Hecht
Publikováno v:
FOM-Edition ISBN: 9783658375461
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed4c781e80971e5416867eb8a339a00
https://doi.org/10.1007/978-3-658-37547-8_9
https://doi.org/10.1007/978-3-658-37547-8_9
Autor:
Andreas Hecht
Publikováno v:
SSRN Electronic Journal.