Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Andreas H Jacobs"'
Autor:
Jennifer Kudelka, Malte Ollenschläger, Richard Dodel, Bjoern M. Eskofier, Markus A. Hobert, Klaus Jahn, Jochen Klucken, Bendix Labeit, M. Cristina Polidori, Tino Prell, Tobias Warnecke, Christine A. F. von Arnim, Walter Maetzler, Andreas H. Jacobs, for the DGG working group Neurology
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background The Comprehensive Geriatric Assessment (CGA) records geriatric syndromes in a standardized manner, allowing individualized treatment tailored to the patient’s needs and resources. Its use has shown a beneficial effect on the fun
Externí odkaz:
https://doaj.org/article/527af05bf2624a8e91e58b533806d719
Autor:
Martha Nowosielski, Matthew D DiFranco, Daniel Putzer, Marcel Seiz, Wolfgang Recheis, Andreas H Jacobs, Günther Stockhammer, Markus Hutterer
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95830 (2014)
OBJECTIVES: Intra-individual spatial overlap analysis of tumor volumes assessed by MRI, the amino acid PET tracer [18F]-FET and the nucleoside PET tracer [18F]-FLT in high-grade gliomas (HGG). METHODS: MRI, [18F]-FET and [18F]-FLT PET data sets were
Externí odkaz:
https://doaj.org/article/42568a444b0346baaaf5b55154599bef
Autor:
Thomas Viel, Sonja Schelhaas, Stefan Wagner, Lydia Wachsmuth, Katrin Schwegmann, Michael Kuhlmann, Cornelius Faber, Klaus Kopka, Michael Schäfers, Andreas H Jacobs
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67911 (2013)
UnlabelledAddition of temozolomide (TMZ) to radiation therapy is the standard treatment for patients with glioblastoma (GBM). However, there is uncertainty regarding the effectiveness of TMZ. Considering the rapid evolution of the disease, methods to
Externí odkaz:
https://doaj.org/article/5b83a89cb35d464b98a1abc32bdbe18f
Autor:
Laura Cerchia, Carla Lucia Esposito, Andreas H Jacobs, Bertrand Tavitian, Vittorio de Franciscis
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7971 (2009)
The hope of success of therapeutic interventions largely relies on the possibility to distinguish between even close tumor types with high accuracy. Indeed, in the last ten years a major challenge to predict the responsiveness to a given therapeutic
Externí odkaz:
https://doaj.org/article/cdbd90ceb13541a98ab2c11d4cd713ba
Autor:
Roland T Ullrich, Thomas Zander, Bernd Neumaier, Mirjam Koker, Takeshi Shimamura, Yannic Waerzeggers, Christa L Borgman, Samir Tawadros, Hongfeng Li, Martin L Sos, Heiko Backes, Geoffrey I Shapiro, Jürgen Wolf, Andreas H Jacobs, Roman K Thomas, Alexandra Winkeler
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3908 (2008)
BACKGROUND: Inhibition of the epidermal growth factor receptor (EGFR) has shown clinical success in patients with advanced non-small cell lung cancer (NSCLC). Somatic mutations of EGFR were found in lung adenocarcinoma that lead to exquisite dependen
Externí odkaz:
https://doaj.org/article/8f3796ed7f8842debdaa3df812da553c
Autor:
Alexandra Winkeler, Miguel Sena-Esteves, Leonie E M Paulis, Hongfeng Li, Yannic Waerzeggers, Benedikt Rückriem, Uwe Himmelreich, Markus Klein, Parisa Monfared, Maria A Rueger, Michael Heneka, Stefan Vollmar, Mathias Hoehn, Cornel Fraefel, Rudolf Graf, Klaus Wienhard, Wolf D Heiss, Andreas H Jacobs
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e528 (2007)
Strategies for non-invasive and quantitative imaging of gene expression in vivo have been developed over the past decade. Non-invasive assessment of the dynamics of gene regulation is of interest for the detection of endogenous disease-specific biolo
Externí odkaz:
https://doaj.org/article/bdc0634e2f6943149f9130268f1ef863
Autor:
Alexander Gerhard, Richard Sharples, Tsepo Goerttler, Kathryn McDonald, Eszter Visi, Rainer Hinz, Federico Turkheimer, Isabel Lewzey, Karl Herholz, Andreas H. Jacobs, Clive Holmes
Publikováno v:
Exploration of Neuroscience, Vol 2, Iss 2, Pp 52-66 (2023)
Aim: Microglial activation is increasingly recognised as a factor in the progression of Alzheimer’s disease (AD) and may be modified by systemic inflammatory signals including serum tumour necrosis factor (TNF)-α. The aim was to investigate whethe
Externí odkaz:
https://doaj.org/article/8e7485364cb346a99bb854966d873498
Autor:
Muriel Heimann, Niklas Schäfer, Christian Bode, Valeri Borger, Lars Eichhorn, Frank A. Giordano, Erdem Güresir, Andreas H. Jacobs, Yon-Dschun Ko, Jennifer Landsberg, Felix Lehmann, Alexander Radbruch, Christina Schaub, Katjana S. Schwab, Johannes Weller, Ulrich Herrlinger, Hartmut Vatter, Patrick Schuss, Matthias Schneider
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectIn the light of an aging population and ongoing advances in cancer control, the optimal management in geriatric patients with brain metastases (BM) poses an increasing challenge, especially due to the scarce data available. We therefore analyze
Externí odkaz:
https://doaj.org/article/8fc4efac84bd411aa7f19cb6b0d3c29a
Autor:
Silvia Valtorta, Alessia Lo Dico, Isabella Raccagni, Cristina Martelli, Valentina Pieri, Paolo Rainone, Sergio Todde, Bastian Zinnhardt, Elisabetta De Bernardi, Angela Coliva, Letterio S. Politi, Thomas Viel, Andreas H. Jacobs, Rossella Galli, Luisa Ottobrini, Valentina Vaira, Rosa Maria Moresco
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is a highly aggressive tumor of the brain. Despite the efforts, response to current therapies is poor and 2-years survival rate ranging from 6-12%. Here, we evaluated the preclinical efficacy of Metformin (MET) as add-on therapy to
Externí odkaz:
https://doaj.org/article/f75ed0e8ab8b4392986f68e1fb538abb
Autor:
Cristina Barca, Claudia Foray, Sven Hermann, Christian Döring, Michael Schäfers, Andreas H. Jacobs, Bastian Zinnhardt
Publikováno v:
NeuroImage, Vol 222, Iss , Pp 117217- (2020)
Introduction: In vivo positron emission tomography (PET) and magnetic resonance imaging (MRI) support non-invasive assessment of the spatiotemporal expression of proteins of interest and functional/structural changes. Our work promotes the use of a v
Externí odkaz:
https://doaj.org/article/644b8cee5de943beaeb32be9aca6dd88