Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andreas Höijer"'
Autor:
Nigel Davies, Daniel Hovdal, Nicholas Edmunds, Peter Nordberg, Anders Dahlén, Aleksandra Dabkowska, Marianna Yanez Arteta, Aurel Radulescu, Tomas Kjellman, Andreas Höijer, Frank Seeliger, Elin Holmedal, Elisabeth Andihn, Nils Bergenhem, Ann-Sofie Sandinge, Camilla Johansson, Leif Hultin, Marie Johansson, Johnny Lindqvist, Liselotte Björsson, Yujia Jing, Stefano Bartesaghi, Lennart Lindfors, Shalini Andersson
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 369-384 (2021)
Lipid nanoparticles (LNPs) are the most clinically advanced delivery system for RNA-based drugs but have predominantly been investigated for intravenous and intramuscular administration. Subcutaneous administration opens the possibility of patient se
Externí odkaz:
https://doaj.org/article/0ab815ddadcf443ab6a9364825393a93
Autor:
Camilla Johansson, Johnny Lindqvist, Lennart Lindfors, Peter Nordberg, Andreas Höijer, Elin Holmedal, Ann-Sofie Sandinge, Marianna Yanez Arteta, Anders Dahlén, Yujia Jing, Elisabeth Andihn, Aurel Radulescu, Leif Hultin, Nicholas Edmunds, Shalini Andersson, Frank Seeliger, Daniel Hovdal, Nils Bergenhem, Nigel Davies, Aleksandra P. Dabkowska, Liselotte Björsson, Stefano Bartesaghi, Tomas Kjellman, Marie Johansson
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss, Pp 369-384 (2021)
Molecular Therapy. Nucleic Acids
Molecular Therapy / Nucleic Acids 24, 369-384 (2021). doi:10.1016/j.omtn.2021.03.008
Molecular Therapy. Nucleic Acids
Molecular Therapy / Nucleic Acids 24, 369-384 (2021). doi:10.1016/j.omtn.2021.03.008
Lipid nanoparticles (LNPs) are the most clinically advanced delivery system for RNA-based drugs but have predominantly been investigated for intravenous and intramuscular administration. Subcutaneous administration opens the possibility of patient se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee74a175a374710935a56c3841d23d0
http://www.sciencedirect.com/science/article/pii/S2162253121000792
http://www.sciencedirect.com/science/article/pii/S2162253121000792
Publikováno v:
Progress in medicinal chemistry. 61
Inhalation of small molecule drugs has proven very efficacious for the treatment of respiratory diseases due to enhanced efficacy and a favourable therapeutic index compared with other dosing routes. It enables targeted delivery to the lung with rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49086127f9b6aaf6491436698570f6c4
https://pubmed.ncbi.nlm.nih.gov/35753716
https://pubmed.ncbi.nlm.nih.gov/35753716
Autor:
Prasath Paramasivam, Christian Franke, Martin Stöter, Andreas Höijer, Stefano Bartesaghi, Alan Sabirsh, Lennart Lindfors, Marianna Yanez Arteta, Anders Dahlén, Annette Bak, Shalini Andersson, Yannis Kalaidzidis, Marc Bickle, Marino Zerial
Publikováno v:
Journal of cell biology, The
The Journal of Cell Biology
The Journal of Cell Biology
Paramasivam et al. compared the endosomal trafficking of six LNP-mRNA formulations. LNP-mRNA accumulates in large endosomes impaired in acidification and unproductive for delivery. Super-resolution microscopy allowed visualization of single LNP-mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc61a8121495d6754b1d0cac82e07022
https://hdl.handle.net/21.11116/0000-000B-0339-2
https://hdl.handle.net/21.11116/0000-000B-0339-2
Autor:
Prasath Paramasivam, Martin Stöter, Eloina Corradi, Irene Dalla Costa, Andreas Höijer, Stefano Bartesaghi, Alan Sabirsh, Lennart Lindfors, Marianna Yanez Arteta, Peter Nordberg, Shalini Andersson, Marie-Laure Baudet, Marc Bickle, Marino Zerial
Detection of nucleic acids within subcellular compartments is key to understanding their function. Determining the intracellular distribution of nucleic acids requires quantitative retention and estimation of their association with different organell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e939bf2c106a9c7f3f8c033e030bb5
http://hdl.handle.net/11572/336895
http://hdl.handle.net/11572/336895
Publikováno v:
Progress in Medicinal Chemistry ISBN: 9780323989039
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c704d04fd07af68aa286e370944ae0aa
https://doi.org/10.1016/bs.pmch.2022.04.001
https://doi.org/10.1016/bs.pmch.2022.04.001
Autor:
Marino Zerial, Lina Lindfors, Eloina Corradi, Martin Stöter, Marianna Yanez Arteta, Shalini Andersson, Marie-Laure Baudet, Prasath Paramasivam, Costa Id, Stefano Bartesaghi, Alan Sabirsh, Marc Bickle, Peter Nordberg, Andreas Höijer
Detection of nucleic acids within sub-cellular compartments is key to understanding their function. Determining the intracellular distribution of nucleic acids requires quantitative retention and estimation of their association with different organel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcaa5ef635b57447c330f7f18ae81f6a
https://doi.org/10.1101/2021.07.06.451306
https://doi.org/10.1101/2021.07.06.451306
Autor:
Shalini Andersson, Stefano Bartesaghi, Prasath Paramasivam, Marc Bickle, Marino Zerial, Alan Sabirsh, Lennart Lindfors, Christian Franke, Annette Bak, Anders Dahlén, Andreas Höijer, Martin Stöter, Yannis Kalaidzidis, Marianna Yanez Arteta
Delivery of exogenous mRNA using lipid nanoparticles (LNP) is a promising strategy for therapeutics. However, a bottleneck remains the poor understanding of the parameters that correlate with endosomal escape vs. cytotoxicity. To address this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::646ca03da0782f7c1f081d5dc217d96d
https://doi.org/10.1101/2020.12.18.423541
https://doi.org/10.1101/2020.12.18.423541