Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Andreas H, Jacobs"'
Autor:
Jennifer Kudelka, Malte Ollenschläger, Richard Dodel, Bjoern M. Eskofier, Markus A. Hobert, Klaus Jahn, Jochen Klucken, Bendix Labeit, M. Cristina Polidori, Tino Prell, Tobias Warnecke, Christine A. F. von Arnim, Walter Maetzler, Andreas H. Jacobs, for the DGG working group Neurology
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background The Comprehensive Geriatric Assessment (CGA) records geriatric syndromes in a standardized manner, allowing individualized treatment tailored to the patient’s needs and resources. Its use has shown a beneficial effect on the fun
Externí odkaz:
https://doaj.org/article/527af05bf2624a8e91e58b533806d719
Autor:
Alexander Gerhard, Richard Sharples, Tsepo Goerttler, Kathryn McDonald, Eszter Visi, Rainer Hinz, Federico Turkheimer, Isabel Lewzey, Karl Herholz, Andreas H. Jacobs, Clive Holmes
Publikováno v:
Exploration of Neuroscience, Vol 2, Iss 2, Pp 52-66 (2023)
Aim: Microglial activation is increasingly recognised as a factor in the progression of Alzheimer’s disease (AD) and may be modified by systemic inflammatory signals including serum tumour necrosis factor (TNF)-α. The aim was to investigate whethe
Externí odkaz:
https://doaj.org/article/8e7485364cb346a99bb854966d873498
Autor:
Imke Ortland, Monique Mendel Ott, Michael Kowar, Christoph Sippel, Yon-Dschun Ko, Andreas H. Jacobs, Ulrich Jaehde
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background To evaluate medication-related risks in older patients with cancer and their association with severe toxicity during antineoplastic therapy. Methods This is a secondary analysis of two prospective, single-center observational stud
Externí odkaz:
https://doaj.org/article/e9af0fc72864439c866367e3968fd8f0
Autor:
Daniela Perani, Leonardo Iaccarino, Andreas H. Jacobs, IMBI Brain Imaging Working Group, Adriaan A. Lammertsma, Agneta Nordberg, Albert D. Windhorst, Alexander Gerhard, Alexandra Winkeler, Anthony Gee, Bertrand Kuhnast, Christer Halldin, David Brooks, Elena Rodriguez‐Vieitez, Federico E. Turkheimer, Francisco López‐Picón, Gitte M. Knudsen, Johnny Vercouillie, Juha O. Rinne, Karl Herholz, Koen Van Laere, Andrea Varrone, Marie Joao Santiago‐Ribeiro, Matthias M. Herth, Michael A. Carroll, Sylvie Chalon, Michel Bottlaender, Oskar Hansson, Paul Edison, Rainer Hinz, Ronald Boellaard, Rosa Maria Moresco, Sabina Pappata
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 327-332 (2019)
Abstract Introduction A rapid transition from a clinical‐based classification to a pathology‐based classification of neurodegenerative conditions, largely promoted by the increasing availability of imaging biomarkers, is emerging. The Framework f
Externí odkaz:
https://doaj.org/article/50bd95b6267e48ed9f70a0858de39d47
Autor:
Cristina Barca, Claudia Foray, Sven Hermann, Ulrich Herrlinger, Isabel Remory, Damya Laoui, Michael Schäfers, Oliver M. Grauer, Bastian Zinnhardt, Andreas H. Jacobs
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunomodulatory therapies have fueled interest in targeting microglial cells as part of the innate immune response after infection or injury. In this context, the colony-stimulating factor 1 (CSF-1) and its receptor (CSF-1R) have gained attention in
Externí odkaz:
https://doaj.org/article/2d102ae257644e63a4c591ed33a74777
Autor:
Muriel Heimann, Niklas Schäfer, Christian Bode, Valeri Borger, Lars Eichhorn, Frank A. Giordano, Erdem Güresir, Andreas H. Jacobs, Yon-Dschun Ko, Jennifer Landsberg, Felix Lehmann, Alexander Radbruch, Christina Schaub, Katjana S. Schwab, Johannes Weller, Ulrich Herrlinger, Hartmut Vatter, Patrick Schuss, Matthias Schneider
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectIn the light of an aging population and ongoing advances in cancer control, the optimal management in geriatric patients with brain metastases (BM) poses an increasing challenge, especially due to the scarce data available. We therefore analyze
Externí odkaz:
https://doaj.org/article/8fc4efac84bd411aa7f19cb6b0d3c29a
Autor:
Silvia Valtorta, Alessia Lo Dico, Isabella Raccagni, Cristina Martelli, Valentina Pieri, Paolo Rainone, Sergio Todde, Bastian Zinnhardt, Elisabetta De Bernardi, Angela Coliva, Letterio S. Politi, Thomas Viel, Andreas H. Jacobs, Rossella Galli, Luisa Ottobrini, Valentina Vaira, Rosa Maria Moresco
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is a highly aggressive tumor of the brain. Despite the efforts, response to current therapies is poor and 2-years survival rate ranging from 6-12%. Here, we evaluated the preclinical efficacy of Metformin (MET) as add-on therapy to
Externí odkaz:
https://doaj.org/article/f75ed0e8ab8b4392986f68e1fb538abb
Autor:
Johanna K. Freundt, Gerrit Frommeyer, Tilmann Spieker, Fabian Wötzel, Jochen Schulze Grotthoff, Jörg Stypmann, Georg Hempel, Michael Schäfers, Andreas H. Jacobs, Lars Eckardt, Philipp S. Lange
Publikováno v:
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background The development of heart failure is accompanied by complex changes in cardiac electrophysiology and functional properties of cardiomyocytes and fibroblasts. Histone deacetylase (HDAC) inhibitors hold great promise for the pharmace
Externí odkaz:
https://doaj.org/article/7efda64f0274422f87b8bbf3dc46c0ac
Autor:
Martin Vychopen, Motaz Hamed, Majd Bahna, Attila Racz, Inja Ilic, Abdallah Salemdawod, Matthias Schneider, Felix Lehmann, Lars Eichhorn, Christian Bode, Andreas H. Jacobs, Charlotte Behning, Patrick Schuss, Erdem Güresir, Hartmut Vatter, Valeri Borger
Publikováno v:
Brain Sciences, Vol 12, Iss 8, p 981 (2022)
Objective: The aim of this study was the verification of the Subdural Hematoma in the Elderly (SHE) score proposed by Alford et al. as a mortality predictor in patients older than 65 years with nontraumatic/minor trauma acute subdural hematoma (aSDH)
Externí odkaz:
https://doaj.org/article/9168ee106c284e969304eec0a9b8abc0
Autor:
Cristina Barca, Claudia Foray, Sven Hermann, Christian Döring, Michael Schäfers, Andreas H. Jacobs, Bastian Zinnhardt
Publikováno v:
NeuroImage, Vol 222, Iss , Pp 117217- (2020)
Introduction: In vivo positron emission tomography (PET) and magnetic resonance imaging (MRI) support non-invasive assessment of the spatiotemporal expression of proteins of interest and functional/structural changes. Our work promotes the use of a v
Externí odkaz:
https://doaj.org/article/644b8cee5de943beaeb32be9aca6dd88