Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Andreas Görlich"'
Autor:
Silke Frahm, Beatriz Antolin-Fontes, Andreas Görlich, Johannes-Friedrich Zander, Gudrun Ahnert-Hilger, Ines Ibañez-Tallon
Publikováno v:
eLife, Vol 4 (2015)
A great deal of interest has been focused recently on the habenula and its critical role in aversion, negative-reward and drug dependence. Using a conditional mouse model of the ACh-synthesizing enzyme choline acetyltransferase (Chat), we report that
Externí odkaz:
https://doaj.org/article/b1cb06f451964e69ac48a6b2986ff9fb
Autor:
Andreas Görlich, Anika-Maria Zimmermann, Doreen Schober, Ralph T Böttcher, Marco Sassoè-Pognetto, Eckhard Friauf, Walter Witke, Marco B Rust
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30068 (2012)
Profilins are important regulators of actin dynamics and have been implicated in activity-dependent morphological changes of dendritic spines and synaptic plasticity. Recently, defective presynaptic excitability and neurotransmitter release of glutam
Externí odkaz:
https://doaj.org/article/df7359ee831a40d4868a42f3c2ea5983
Autor:
Andreas Görlich, Michael Wolf, Anika-Maria Zimmermann, Christine B Gurniak, Mumna Al Banchaabouchi, Marco Sassoè-Pognetto, Walter Witke, Eckhard Friauf, Marco B Rust
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26789 (2011)
Actin plays important roles in a number of synaptic processes, including synaptic vesicle organization and exocytosis, mobility of postsynaptic receptors, and synaptic plasticity. However, little is known about the mechanisms that control actin at sy
Externí odkaz:
https://doaj.org/article/1ce53aeb0ed04f3c9881bd234b7fe7dc
Autor:
Jianxi Liu, Andreas Görlich, Sylvia M. Lipford, Nathaniel Heintz, Inés Ibañez-Tallon, Cuidong Wang, Maya Williams, Jessica L. Ables, Michael H. Riad, Kun Li, Maria Dao, Henrik Molina, Paul J. Kenny, Beatriz Antolin-Fontes
Publikováno v:
Proc Natl Acad Sci U S A
The habenula, an ancient small brain area in the epithalamus, densely expresses nicotinic acetylcholine receptors and is critical for nicotine intake and aversion. As such, identification of strategies to manipulate habenular activity may yield appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229f29a92efc87000492443bb9644f95
https://pubmed.ncbi.nlm.nih.gov/32098843
https://pubmed.ncbi.nlm.nih.gov/32098843
Autor:
Dao M, Michael H. Riad, Paul J. Kenny, Beatriz Antolin-Fontes, Kun Li, Henrik Molina, Sylvia M. Lipford, Jessica L. Ables, Jianjun Liu, Inés Ibañez-Tallon, Andreas Görlich, Maya Williams, Cuidong Wang
SUMMARYThe habenula controls the addictive properties of nicotine but also densely expresses opioid and cannabinoid receptors. As such, identification of strategies to manipulate habenular activity may yield new approaches to treat substance use diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96435bf0932c4164ccbbc2dc57f7f1f
Publikováno v:
Neuropharmacology. 96:213-222
Progress has been made over the last decade in our understanding of the brain areas and circuits involved in nicotine reward and withdrawal, leading to models of addiction that assign different addictive behaviors to distinct, yet overlapping, neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc066180d3ffe142f29aaf7d55332418
https://doi.org/10.1016/j.neuropharm.2014.11.019
https://doi.org/10.1016/j.neuropharm.2014.11.019
Autor:
Cuidong Wang, Nathaniel Heintz, Jessica L. Ables, Minmin Luo, Paul J. Kenny, Beatriz Antolin-Fontes, Jing Ren, Fei Hu, Sylvia M. Lipford, Inés Ibañez-Tallon, Michael H. Riad, Andreas Görlich
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(49)
Repeated exposure to drugs of abuse can produce adaptive changes that lead to the establishment of dependence. It has been shown that allelic variation in the α5 nicotinic acetylcholine receptor (nAChR) gene CHRNA5 is associated with higher risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba84976192431440991dabd3be0adb30
https://pubmed.ncbi.nlm.nih.gov/29158387
https://pubmed.ncbi.nlm.nih.gov/29158387
Publikováno v:
Cell. 159:295-305
Summary Human imaging studies have revealed that intranasal administration of the "prosocial" hormone oxytocin (OT) activates the frontal cortex, and this action of OT correlates with enhanced brain function in autism. Here, we report the discovery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba97123f5a255c21f1915ff2bf84ded
https://doi.org/10.1016/j.cell.2014.09.020
https://doi.org/10.1016/j.cell.2014.09.020
Autor:
Marco B. Rust, Christine B. Gurniak, Anika-Maria Zimmermann, Andreas Görlich, Walter Witke, Michael Wolf, Eckhard Friauf, Marco Sassoè-Pognetto
Publikováno v:
Cerebral Cortex. 25:2863-2875
Actin is a regulator of synaptic vesicle mobilization and exocytosis, but little is known about the mechanisms that regulate actin at presynaptic terminals. Genetic data on LIMK1, a negative regulator of actin-depolymerizing proteins of the ADF/cofil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a086e7cecb947c2db8d26d35e61195
https://doi.org/10.1093/cercor/bhu081
https://doi.org/10.1093/cercor/bhu081
Autor:
Paul Strecker, Marco B. Rust, Suzanne Y. Guénette, Tabea A. Mundinger, Christina Mehrfeld, Elisa G. Krächan, Martin Korte, Andreas Görlich, Stefan Kins, Joachim Herz, Susann Ludewig
Publikováno v:
Scientific Reports
The FE65 adaptor proteins (FE65, FE65L1 and FE65L2) bind proteins that function in diverse cellular pathways and are essential for specific biological processes. Mice lacking both FE65 and FE65L1 exhibit ectopic neuronal positioning in the cortex and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d205a567e8bdad67335df6a2cea99f6
https://pubmed.ncbi.nlm.nih.gov/27734846
https://pubmed.ncbi.nlm.nih.gov/27734846