Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andreas E. Roussidis"'
Autor:
Dimitris Kletsas, Achileas D. Theocharis, Chrisostomi Gialeli, Christina J. Malavaki, Nikos K. Karamanos, Theodore Tsegenidis, Andreas E. Roussidis, George N. Tzanakakis
Publikováno v:
FEBS Journal. 280:2477-2489
Cell surface heparan sulfate proteoglycans (HSPGs), syndecans and glypicans, play crucial roles in the functional properties of cancer cells, such as proliferation, adhesion, migration and invasion. Platelet-derived growth factor (PDGF)/PDGF receptor
Autor:
George N. Tzanakakis, Andreas E. Roussidis, Olga Ch. Kousidou, Nikos K. Karamanos, Ioannis K. Kostakis, Panagiotis Marakos, Nicole Pouli
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:3445-3455
A series of novel aminosubstituted xantheno[1,2-d]imidazole derivatives have been designed and synthesized and their antiproliferative activity has been evaluated against human breast MDA-MB-231 cell line. Among the tested compounds those bearing two
Autor:
George N. Tzanakakis, Andreas E. Roussidis, Nikos K. Karamanos, Olga Ch. Kousidou, Xanthi N. Stahtea
Publikováno v:
Connective Tissue Research. 49:211-214
Critical steps for cancer cell growth, migration, invasion, and metastasis are the interactions of extracellular matrix (ECM) molecules with cells, the disconnection of intercellular adhesion, and the degradation of ECM. The latter is mediated mainly
Publikováno v:
Current Medicinal Chemistry. 14:735-743
Molecular therapies target key functional molecules in order to halter viable operation of cancer cells. Receptor tyrosine kinases (RTKs) constitute attractive targets, as quite often their abnormal signaling has been associated with tumor developmen
Autor:
Athanasios Skoutelis, Andreas E. Roussidis, Evangelos Gikas, Anthony Tsarbopoulos, Panagiotis Fanourgiakis, Efstathia Perivolioti, Fotini N. Bazoti
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 51(4)
A rapid and simple method based on ultra performance liquid chromatography (UPLC) with ultra violet detection has been developed for the determination of daptomycin (DPT) and rifampicin (RFM) in rabbit plasma using 4-nitrophenol as internal standard
Autor:
Athanasios Skoutelis, Efstathia Perivolioti, Anthony Tsarbopoulos, Evagelos Gikas, Andreas E. Roussidis, Fotini N. Bazoti, Panagiotis Fanourgiakis
Publikováno v:
Biomedical Chromatography.
Daptomycin (DPT) is a lipopeptide antibiotic with potent bactericidal activity in vitro against Gram-positive bacteria, which has attracted the attention of the scientific community due to its unique mechanism of action and due to the immediate need
Autor:
Andreas E. Roussidis, Dimitris Kletsas, Theodoros Karampinas, Nikos K. Karamanos, Vassiliki Gioni, Gerassimos Voutsinas, Savvas Papadopoulos
Publikováno v:
Molecular cancer research : MCR. 6(5)
Tumor stroma plays an important role in cancer development. In a variety of tumors, such as breast carcinomas, a desmoplastic response, characterized by stromal fibroblast and collagen accumulation, is observed having synergistic effects on tumor pro
Autor:
Nikos K. Karamanos, Olga Ch. Kousidou, Achilleas D. Theocharis, T. N. Mitropoulou, Andreas E. Roussidis, D. Kletsas
Publikováno v:
International Journal of Oncology.
Progression of breast cancer implicates the degradation of extracellular matrix (ECM) by metalloproteinases (MMPs), a process with important consequences on the growth and invasiveness of cancer cells in adjacent and distant sites. The isoflavone, ge
Publikováno v:
Biomedical chromatography : BMC. 18(3)
Matrix glycoproteins are among the main components that contribute to the properties of cartilage. In this article we report on the development of a rapid method for the fractionation and purification of a 92 kDa glycoprotein from chick sternal carti
Publikováno v:
In vivo (Athens, Greece). 16(6)
Every cell in a multicellular organism receives signals from the extracellular matrix and neighboring cells. These signals are transmitted, via transmembrane receptors and cascade proteins of the intracellular message system, inside the cell and ofte