Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Andreas D. Schenk"'
Autor:
Varun Bhaskar, Alexandra Graff-Meyer, Andreas D. Schenk, Simone Cavadini, Ottilie von Loeffelholz, S. Kundhavai Natchiar, Caroline G. Artus-Revel, Hans-Rudolf Hotz, Gabriel Bretones, Bruno P. Klaholz, Jeffrey A. Chao
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: Ribosomes undergo multiple conformational transitions during translation elongation. Here, we report the high-resolution cryoelectron microscopy (cryo-EM) structure of the human 80S ribosome in the post-decoding pre-translocation state (clas
Externí odkaz:
https://doaj.org/article/ab271bc4b7cf423480279f3743614470
Autor:
Andreas D. Schenk, Simone Cavadini, Jessica Desogus, Varun Bhaskar, Alexandra Graff-Meyer, Jeffrey A. Chao
Publikováno v:
RNA
Ribosomes are the macromolecular machines at the heart of protein synthesis; however, their function can be modulated by a variety of additional protein factors that directly interact with them. Here, we report the cryo-EM structure of human Ebp1 (p4
Publikováno v:
Journal of Chemical Information and Modeling. 60:2561-2569
Efficient, reproducible and accountable single-particle cryo-electron microscopy structure determination is tedious and often impeded by lack of a standardized procedure for data analysis and processing. To address this issue, we have developed the F
Autor:
Andreas D. Schenk, Weaam I. Mohamed, Georg Kempf, Anja Basters, Alessandro Potenza, Simone Cavadini, Kurt M. Reichermeier, Wassim Abdul Rahman, Julius Rabl, Nicolas H. Thomä
Publikováno v:
The EMBO Journal
The EMBO Journal, 40 (22)
The EMBO Journal, 40 (22)
The cullin-4-based RING-type (CRL4) family of E3 ubiquitin ligases functions together with dedicated substrate receptors. Out of the similar to 29 CRL4 substrate receptors reported, the DDB1- and CUL4-associated factor 1 (DCAF1) is essential for cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fcf45367ecd8e8de975a053e679ff5
https://resolver.caltech.edu/CaltechAUTHORS:20211021-201507835
https://resolver.caltech.edu/CaltechAUTHORS:20211021-201507835
Autor:
Daniel Hess, Simone Cavadini, Andreas D. Schenk, Jan Seebacher, Jeffrey A. Chao, Julia Nörpel, Varun Bhaskar, Alexandra Graff-Meyer
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001344 (2021)
PLoS Biology
PLoS Biology
A major cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) spectrum disorder is the hexanucleotide G4C2 repeat expansion in the first intron of the C9orf72 gene. Many underlying mechanisms lead to manifestation of
Autor:
Andreas D. Schenk, Julius Rabl, Alessandro Potenza, Junpei Yamamoto, Dirk Schübeler, Ralph S. Grand, Shigenori Iwai, Simone Cavadini, Hitoshi Kurumizaka, Syota Matsumoto, Richard D. Bunker, Kaoru Sugasawa, Nicolas H. Thomä
Publikováno v:
Nature
Access to DNA packaged in nucleosomes is critical for gene regulation, DNA replication and DNA repair. In humans, the UV-damaged DNA-binding protein (UV-DDB) complex detects UV-light-induced pyrimidine dimers throughout the genome; however, it remain
Autor:
Nicolas H. Thomä, Lukas Burger, Richard D. Bunker, Georg Kempf, Zuzanna Kozicka, Syota Matsumoto, Dirk Schübeler, Luke Isbel, Ralph S. Grand, Andreas D. Schenk, Alicia K. Michael, Alexandra Graff-Meyer, Ganesh R. Pathare, Simone Cavadini, Joscha Weiss
Publikováno v:
Science
Engaging the nucleosome Cell identity is defined by gene expression patterns that are established through the binding of specific transcription factors. However, nucleosomal units limit access of transcription factors to specific DNA motifs within th
Autor:
S. Kundhavai Natchiar, Gabriel Bretones, Simone Cavadini, Varun Bhaskar, Ottilie von Loeffelholz, Jeffrey A. Chao, Caroline G Artus-Revel, Bruno P. Klaholz, Hans-Rudolf Hotz, Andreas D. Schenk, Alexandra Graff-Meyer
Publikováno v:
Scopus
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Cell Reports
Cell Reports, Elsevier Inc, 2020, 31 (1), pp.107473. ⟨10.1016/j.celrep.2020.03.037⟩
Cell Reports, 2020, 31 (1), pp.107473. ⟨10.1016/j.celrep.2020.03.037⟩
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Cell Reports, Vol 31, Iss 1, Pp-(2020)
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Cell Reports
Cell Reports, Elsevier Inc, 2020, 31 (1), pp.107473. ⟨10.1016/j.celrep.2020.03.037⟩
Cell Reports, 2020, 31 (1), pp.107473. ⟨10.1016/j.celrep.2020.03.037⟩
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Cell Reports, Vol 31, Iss 1, Pp-(2020)
Summary: Ribosomes undergo multiple conformational transitions during translation elongation. Here, we report the high-resolution cryoelectron microscopy (cryo-EM) structure of the human 80S ribosome in the post-decoding pre-translocation state (clas
Autor:
Stefan Scheuber, Ansgar Philippsen, Torsten Schwede, Jürgen Haas, Marco Biasini, Valerio Mariani, Andreas D. Schenk
Publikováno v:
Bioinformatics
Motivation: Developers of new methods in computational structural biology are often hampered in their research by incompatible software tools and non-standardized data formats. To address this problem, we have developed OpenStructure as a modular ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d10c640b9b4754275cca0529a562c20
http://doc.rero.ch/record/303297/files/btq481.pdf
http://doc.rero.ch/record/303297/files/btq481.pdf
Autor:
Shigenori Iwai, Nicolas H. Thomä, Kaoru Sugasawa, Simone Cavadini, Dirk Schübeler, Julius Rabl, Hitoshi Kurumizaka, Junpei Yamamoto, Andreas D. Schenk, Richard D. Bunker, Alessandro Potenza, Ralph S. Grand, Syota Matsumoto
Publikováno v:
Nature. 571:E6-E6
In this Article, in Fig. 1a, the 5' and 3' labels were reversed in the DNA sequence, and Fig. 4 was missing panel labels a-e. These errors have been corrected online.