Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Andreas Czwalinna"'
Autor:
Kerstin Jurk, Anke Adenaeuer, Stefanie Sollfrank, Kathrin Groß, Friederike Häuser, Andreas Czwalinna, Josef Erkel, Nele Fritsch, Dana Marandiuc, Martin Schaller, Karl J. Lackner, Heidi Rossmann, Frauke Bergmann
Publikováno v:
Cells, Vol 11, Iss 19, p 3071 (2022)
Germline defects in the transcription factor GATA1 are known to cause dyserythropoiesis with(out) anemia and variable abnormalities in platelet count and function. However, damaging variants closely located to the C-terminal zinc finger domain of GAT
Externí odkaz:
https://doaj.org/article/a8cbb3c86a184c079babd3ae268763de
Autor:
Kerstin, Jurk, Anke, Adenaeuer, Stefanie, Sollfrank, Kathrin, Groß, Friederike, Häuser, Andreas, Czwalinna, Josef, Erkel, Nele, Fritsch, Dana, Marandiuc, Martin, Schaller, Karl J, Lackner, Heidi, Rossmann, Frauke, Bergmann
Publikováno v:
Cells. 11(19)
Germline defects in the transcription factor GATA1 are known to cause dyserythropoiesis with(out) anemia and variable abnormalities in platelet count and function. However, damaging variants closely located to the C-terminal zinc finger domain of GAT
Autor:
Ulrich J. Sachs, Nina Cooper, Karina Althaus, Andreas Tiede, Jens Müller, Andreas Czwalinna, Bernd Pötzsch
Publikováno v:
Thrombosis and Haemostasis. 121:1622-1627
Background Coronavirus disease 2019 vaccine ChAdOx1 nCov-19 may rarely lead to vaccine-induced thrombotic thrombocytopenia (VITT). Antibody-mediated, platelet factor 4 (PF4)-dependent platelet activation appears to resemble a key mechanism in VITT, p
Autor:
Andreas Tiede, Heiner Wedemeyer, Sonja Werwitzke, Frank Gf Donnerstag, Arnold Ganser, Ulrich J. Sachs, Andreas Czwalinna, Günter U. Höglinger, Benjamin Maasoumy, Joachim K. Krauss, Karin Weißenborn, Rolf Bikker
Publikováno v:
Blood
We report 5 cases of prothrombotic immune thrombocytopenia after exposure to the ChAdOx1 vaccine (AZD1222, Vaxzevria) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients presented 5 to 11 days after first vaccination. The s
Autor:
Andreas Czwalinna, F. Bergmann
Publikováno v:
Hamostaseologie. 40(2)
Despite a lot of research on antiphospholipid antibodies (aPL), standardization of test systems, and better definition of its clinical symptoms, the pathomechanism of this acquired autoimmune disease is not yet fully explained. Progress in treatment
Autor:
Annette Westermann, Andreas Czwalinna, Arnold Ganser, Carsten Müller-Tidow, Walter Verbeek, Jürgen Krauter, Gerhard Heil, Jens Tiesmeier, Mandy Hoffmann, Hubert Serve
Publikováno v:
Leukemia Research. 28:1069-1074
Internal tandem duplications (ITDs) of the juxtamembrane region of the FLT3 tyrosine kinase receptor are the most frequent genetic alterations in acute myeloid leukemia (AML). The presence of this mutation has been recognized as an independent poor p
Autor:
Walter Verbeek, Gerhard Heil, Jens Tiesmeier, Hubert Serve, Jürgen Krauter, Arnold Ganser, Carsten Müller-Tidow, Andreas Czwalinna
Publikováno v:
British Journal of Haematology. 123:413-419
Transcription factor CCAAT/enhancer binding protein alpha (C/EBPalpha) is mutated in 6-10% of patients with acute myeloid leukaemia (AML). Recently, we reported the emergence of an N-terminal C/EBPalpha mutation after chemotherapy in a patient with s
Autor:
Arnold Ganser, Silke Ehrenforth, Inge Scharrer, Mario von Depka, Roswith Eisert, Andreas Czwalinna, C. Wermes
Publikováno v:
Thrombosis and Haemostasis. 89:847-852
SummaryACE displays potent vasoconstrictive effects, attenuation of fibrinolysis, and platelet activation and aggregation, thus possibly promoting venous thromboembolism (VTE). The ACE gene contains an insertion (I) or deletion (D) polymorphism accou
Autor:
Kathrin Schwierczek, Frauke Bergmann, Ulrich Walter, Kerstin Jurk, Andreas Czwalinna, Stefanie Sollfrank, Karl J. Lackner, Heidi Rossmann, Joseph Erkel
Publikováno v:
Blood. 128:2557-2557
Aims :We report about a 35 year old male patient with severe and frequent epistaxis and hematoma since infancy. He presented with mild thrombocytopenia and increased mean platelet volume. Von Willebrand's disease and subhemophilia had been excluded.
Publikováno v:
Annals of hematology. 89(6)
The aetiology of anti-factor VIII (FVIII) autoantibody formation in acquired haemophilia remains unknown. We hypothesised that encounter of antigenically different, allogeneic FVIII may challenge inhibitor formation after presentation on MHC class II