Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andreas C. Gidlöf"'
Autor:
Andreas C. Gidlöf, Anders Oldner, Emma Larsson, Ola Friman, Olof Brattström, Mikael Eriksson, Elisabeth Hellgren, Jesper Eriksson
Publikováno v:
Journal of Critical Care. 54:125-129
Purpose To evaluate the performance of the new SOFA-based sepsis definition in trauma patients. Materials and methods A single-centre, retrospective, observational study. Primary outcome was 30-day mortality including a censoring analysis for early d
Autor:
Anders Oldner, Jesper Eriksson, Emma Larsson, Mikael Eriksson, Olof Brattström, Andreas C. Gidlöf
Publikováno v:
Free radical biologymedicine. 104
Background Thioredoxin (TRX), an endogenous anti-oxidant protein induced in inflammatory conditions, has been shown to increase in plasma and to be associated with outcome in septic patients. This biomarker has never been studied in a trauma setting.
Autor:
Pauline Ocaya, Ali Ateia Elmabsout, Hans Törmä, Peder S. Olofsson, Andreas C. Gidlöf, Allan Sirsjö
Publikováno v:
Journal of Vascular Research. 48:23-30
Aim: The cytochrome P450 enzymes of the CYP26 family are involved in the catabolism of the biologically active retinoid all-trans-retinoic acid (atRA). Since it is possible that an increased local CYP26 activity would reduce the effects of retinoids
Vitamin A: a drug for prevention of restenosis/reocclusion after percutaneous coronary intervention?
Publikováno v:
Clinical Science. 114:19-25
The re-establishment of adequate blood flow in a vessel with a reduced lumen due to an atherosclerotic plaque by percutaneous vascular intervention is a well established procedure. However, the long-term outcome of such interventions is negatively in
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:1542-1548
Objective— Intimal smooth muscle cells (SMCs) are dedifferentiated SMCs that have a powerful ability to proliferate and migrate. This cell-type is responsible for the development of intimal hyperplasia after vascular angioplasty. Retinoids, especia
Publikováno v:
Journal of Vascular Research. 43:392-398
Vascular disease is multifactorial and smooth muscle cells (SMCs) play a key role. Retinoids have been shown to influence many disease-promoting processes including proliferation and differentiation in the vessel wall. Phenotypic heterogeneity of vas
Autor:
Giulio Gabbiani, Michael S. Pepper, Zhong-qun Yan, Allan Sirsjö, Pascal Neuville, Andreas C. Gidlöf, Göran K. Hansson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 19:1430-1436
Abstract —We have recently shown that all- trans retinoic acid (tRA) modulates arterial smooth muscle cell (SMC) morphologic features and biochemical composition in vitro. It has been proposed that different SMC phenotypes coexist in arteries, whic
Publikováno v:
Biochemical and biophysical research communications. 286(2)
Retinoids have been shown to modulate inflammation and the immune response in many cell types including macrophages, endothelial cells, and vascular smooth muscle cells. However, present knowledge of whether inflammatory mediators modulate vitamin A
Autor:
Mikko P. S. Ares, Ulrich Förstermann, Göran K. Hansson, Allan Sirsjö, Hans Törmä, Anneli Olsson, Andreas C. Gidlöf, Hartmut Kleinert
Publikováno v:
Biochemical and biophysical research communications. 270(3)
Retinoids are multipotent modulators of cellular functions and suppress cytokine-induced production of nitric oxide (NO) in several cell types. We have explored the mechanisms by which retinoic acid (RA) regulates NO production in rat aortic smooth m
Publikováno v:
The European journal of surgery = Acta chirurgica. 166(2)
To investigate the effect of synthetic retinoids on septic shock induced by lipopolysaccharide (LPS) in rats.Randomised study.University hospital laboratory, Sweden.31 male Sprague Dawley rats randomised into four groups: controls, given vehicle alon