Výsledky vyhledávání - "Andreas Bruchbacher"

Akademický článek

Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis

Autor: Bettina Trimmel, Andre Oszwald, Christoph Diemand, Iris E. Ertl, Ursula Lemberger, Andreas Bruchbacher, Robert Brettner, Stephan Korn, Irene Resch, Eva Comperat, Shahrokh F. Shariat, Melanie R. Hassler

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)

Abstract Squamous cell carcinoma of the penis (PSC) is a rare disease with limited information on the molecular events leading to malignant transformation. In a third of PSC cases, presence of human papilloma virus (HPV) is found. The APOBEC3 family

Externí odkaz: https://doaj.org/article/3aa2b5c569dc4bdc90c7d05d36bb9d7e

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Akademický článek

Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer

Publikováno v: Cells, Vol 9, Iss 8, p 1839 (2020)

Background: Bacillus Calmette-Guérin (BCG) immunotherapy, the standard adjuvant intravesical therapy for some intermediate and most high-risk non-muscle invasive bladder cancers (NMIBCs), suffers from a heterogenous response rate. Molecular markers

Externí odkaz: https://doaj.org/article/837a12d883f24e87bf5c66e235db5396

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Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound

Publikováno v: European Urology. 82:261-270

The heterogeneity of bladder cancers (BCs) is a major challenge for the development of novel therapies. However, given the high rates of recurrence and/or treatment failure, the identification of effective therapeutic strategies is an urgent clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a645a3f3589cd9885e3dc52540f270ca
https://doi.org/10.1016/j.eururo.2022.03.009

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The microbiome in urinary tract infections in children – an update

Autor: Ursula Lemberger, Shahrokh F. Shariat, Manuela Hiess, Andreas Bruchbacher, Fahad Quhal

Publikováno v: Current Opinion in Urology. 31:147-154

Purpose of review Urinary tract infection (UTI) is one of the most common pediatric infections worldwide. Recently introduced 16S rRNA sequencing allows detailed identification of bacteria involved in UTI on a species-based level. The urogenital micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b15320cb4bbdb61f12a8906cb405fe
https://doi.org/10.1097/mou.0000000000000858

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MP40-16 EXPRESSION ANALYSIS AND MUTATIONAL STATUS OF HISTONE METHYLTRANSFERASE KMT2D IN UPPER TRACT UROTHELIAL CARCINOMA

Autor: Ekaterina Laukhtina, Ursula Lemberger, Andreas Bruchbacher, Dafina Ilijazi, David D’Andrea, Martin Susani, Dmitry Enikeev, Eva Compérat, Shahrokh F. Shariat, Melanie R. Hassler

Publikováno v: Journal of Urology. 207

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae7e68e0fa563a2204bcff824fdc4b76
https://doi.org/10.1097/ju.0000000000002600.16

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Systemic therapy for metastatic renal cell carcinoma in the first-line setting: a systematic review and network meta-analysis

Autor: Stefano Luzzago, Benjamin Pradere, Manuela Schmidinger, Shahrokh F. Shariat, Pierre I. Karakiewicz, Hadi Mostafaei, Keiichiro Mori, Andreas Bruchbacher, Noriyoshi Miura, Shin Egawa

Publikováno v: Cancer Immunology, Immunotherapy

Purpose Management of metastatic renal cell cancer (mRCC) has undergone a paradigm shift with immune-checkpoint inhibitors (ICI) in the first-line setting. However, direct comparative data are inadequate to inform treatment decisions. Therefore, we a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b73d5c8e82462e07dae33c2c4a3b9a
http://europepmc.org/articles/PMC7889529

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Poly(ADP-ribose) polymerase inhibitors in prostate and urothelial cancer

Autor: Stephan Brönimann, Shahrokh F. Shariat, Andreas Bruchbacher, Melanie R. Hassler, Ursula Lemberger

Publikováno v: Current Opinion in Urology. 30:519-526

Purpose of review The aim of this article is to give an overview of poly(ADP-ribose) polymerase inhibitors (PARPis) trials in prostate cancer and to discuss emerging approaches with potential future clinical implementation in both prostate and urothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec032bb027bf36e12d322b2ee8e0cde
https://doi.org/10.1097/mou.0000000000000776

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PD1/PD-L1 therapy in metastatic renal cell carcinoma

Autor: Melanie R. Hassler, Harun Fajkovic, Ursula Lemberger, Manuela Schmidinger, Andreas Bruchbacher

Publikováno v: Current Opinion in Urology. 30:534-541

Purpose of review The aim of the article to summarize recent changes of treatment options in metastatic renal cell carcinoma (mRCC) with a special emphasis on immune checkpoint inhibition. Recent findings The introduction of checkpoint inhibitor (CPI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90eecf81702c40385a62b9d11356b07
https://doi.org/10.1097/mou.0000000000000788

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