Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Andreas Bracher"'
Autor:
Matthias M. Schneider, Saurabh Gautam, Therese W. Herling, Ewa Andrzejewska, Georg Krainer, Alyssa M. Miller, Victoria A. Trinkaus, Quentin A. E. Peter, Francesco Simone Ruggeri, Michele Vendruscolo, Andreas Bracher, Christopher M. Dobson, F. Ulrich Hartl, Tuomas P. J. Knowles
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Molecular chaperones from the Hsp70 family can break up protein aggregates, including amyloids. Here, the authors utilize microfluidic diffusional sizing to assess the mechanism of α-synuclein (αS) disaggregation by the Hsc70–DnaJB1–Apg2 system
Externí odkaz:
https://doaj.org/article/9d156d4ff127467f8d1a03fe03aed8f5
Autor:
Luca Zinzula, Angela Maria Mereu, Massimiliano Orsini, Christine Seeleitner, Andreas Bracher, István Nagy, Wolfgang Baumeister
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105354- (2022)
Summary: Ebola virus (EBOV) and Marburg virus (MARV) are highly pathogenic viruses in humans, against which approved antivirals are lacking. During EBOV and MARV infection, coiled-coil mediated oligomerization is essential for the virion protein 35 (
Externí odkaz:
https://doaj.org/article/69620d0ff5dc4373b4b7673912cb9335
Autor:
Patricia Yuste-Checa, Victoria A. Trinkaus, Irene Riera-Tur, Rahmi Imamoglu, Theresa F. Schaller, Huping Wang, Irina Dudanova, Mark S. Hipp, Andreas Bracher, F. Ulrich Hartl
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Variants of the extracellular chaperone Clusterin are associated with Alzheimer’s disease (AD) and Clusterin levels are elevated in AD patient brains. Here, the authors show that Clusterin binds to oligomeric Tau, which enhances the seeding capacit
Externí odkaz:
https://doaj.org/article/6817e37ab6504c1fa561f4ad2a667e95
Autor:
Andreas Bracher, Simanta S Paul, Huping Wang, Nadine Wischnewski, F Ulrich Hartl, Manajit Hayer-Hartl
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230090 (2020)
Chaperonins are ubiquitous molecular chaperones found in all domains of life. They form ring-shaped complexes that assist in the folding of substrate proteins in an ATP-dependent reaction cycle. Key to the folding cycle is the transient encapsulation
Externí odkaz:
https://doaj.org/article/6fa832ffdb6c4307a1d5b9e22bf8b01a
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135448 (2015)
The most prevalent form of the Rubisco enzyme is a complex of eight catalytic large subunits (RbcL) and eight regulatory small subunits (RbcS). Rubisco biogenesis depends on the assistance by specific molecular chaperones. The assembly chaperone RbcX
Externí odkaz:
https://doaj.org/article/8018cee3ee3442d9bef399e5eec1a8e5
Autor:
Andreas Bracher, Jacob Verghese
Publikováno v:
Subcellular Biochemistry ISBN: 9783031147395
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b62f34ecb84f29a756560b0ce1af6649
https://doi.org/10.1007/978-3-031-14740-1_1
https://doi.org/10.1007/978-3-031-14740-1_1
Autor:
Andreas, Bracher, Jacob, Verghese
Publikováno v:
Sub-cellular biochemistry. 101
Molecular chaperones of the Hsp70 family are key components of the cellular protein-folding machinery. Substrate folding is accomplished by iterative cycles of ATP binding, hydrolysis, and release. The ATPase activity of Hsp70 is regulated by two mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f241fbfc636d094788c1ea44a0b9716b
https://pubmed.ncbi.nlm.nih.gov/36520302
https://pubmed.ncbi.nlm.nih.gov/36520302
Autor:
Andreas BRACHER
The Catholic church in the nineteenth century was still a formidable power in the European world, with a large and devout following of believers. But it was deeply connected with the ancient feudal world, the influence of which was gradually waning i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204c445e5f8bb1719eeffa0e5dc83d72
Autor:
Tuomas P. J. Knowles, Christopher M. Dobson, Quentin Peter, Ewa Andrzejewska, Michele Vendruscolo, Matthias Schneider, Georg Krainer, F. Ulrich Hartl, Therese W. Herling, Francesco Simone Ruggeri, Andreas Bracher, Alyssa M. Miller, Victoria A. Trinkaus, Saurabh Gautam
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications 12 (2021) 1
Nature Communications, 12(1)
Nature Communications
Nature Communications 12 (2021) 1
Nature Communications, 12(1)
Nature Communications
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8967e9c4097b3a3e489f15404c20957
https://doaj.org/article/9d156d4ff127467f8d1a03fe03aed8f5
https://doaj.org/article/9d156d4ff127467f8d1a03fe03aed8f5
Autor:
Martha C. Taubert, Jürgen M. Kolos, Christian Meyners, Thomas M. Geiger, Andreas Bracher, Patrick L. Purder, Tim Heymann, Pablo Wessig, Andreas M. Voll, Nils C. Gassen, Anna Charalampidou, Felix Hausch, Stephanie Merz, Thomas Bajaj
Publikováno v:
Angewandte Chemie. 133:13366-13372
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7ccf4922205c36b9eb05b01bf872ee
https://doi.org/10.1002/ange.202017352
https://doi.org/10.1002/ange.202017352