Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andreas Bickert"'
Autor:
Andreas Bickert, Christina Ginkel, Matthijs Kol, Katharina vom Dorp, Holger Jastrow, Joachim Degen, René L. Jacobs, Dennis E. Vance, Elke Winterhager, Xian-Cheng Jiang, Peter Dörmann, Pentti Somerharju, Joost C.M. Holthuis, Klaus Willecke
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 4, Pp 821-835 (2015)
Besides bulk amounts of SM, mammalian cells produce small quantities of the SM analog ceramide phosphoethanolamine (CPE). Little is known about the biological role of CPE or enzymes responsible for CPE production. Heterologous expression studies reve
Externí odkaz:
https://doaj.org/article/b55343a153c440909b926aa8cdb55ae3
Autor:
Andreas Bickert, Stefanie Herresthal, Dieter Hartmann, Martina van Uelft, Reinhard Bauer, Joachim Degen, Peter Dörmann, Konrad Sandhoff, Thomas Ulas, Klaus Willecke, Paul Kern, Bernadette Breiden, Katharina Gutbrod, Joachim L. Schultze
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863:734-749
The replacement of two consecutive histidine residues by alanine residues in the catalytic center of ceramide synthase 2 in a new transgenic mouse mutant (CerS2 H/A) leads to inactivation of catalytic activity and reduces protein level to 60% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49da5ae5a1e27573520118131e32041
https://doi.org/10.1016/j.bbalip.2018.04.006
https://doi.org/10.1016/j.bbalip.2018.04.006
Autor:
Konrad Schultz, Bianca Brüggen, Christiane Kremser, Klaus Willecke, Andreas Bickert, Philipp Ebel, Katharina vom Dorp, Karin Dedek, Peter Dörmann
Publikováno v:
European Journal of Neuroscience. 44:1700-1713
Complex sphingolipids are strongly expressed in neuronal tissue and contain ceramides in their backbone. Ceramides are synthesized by six ceramide synthases (CerS1-6). Although it is known that each tissue has a unique profile of ceramide synthase ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8aa0770a9aa2ca4b722802d8a706e07
https://doi.org/10.1111/ejn.13260
https://doi.org/10.1111/ejn.13260
Autor:
Andreas Bickert, Matthijs Kol, Sergei Korneev, Joost C. M. Holthuis, Angelika Hilderink, John G. Mina, Birol Cabukusta, Laura Kneller
Publikováno v:
Scientific Reports
Scientific reports, 2017, Vol.7, pp.41290 [Peer Reviewed Journal]
Scientific reports, 2017, Vol.7, pp.41290 [Peer Reviewed Journal]
SMSr/SAMD8 is an ER-resident ceramide phosphoethanolamine synthase with a critical role in controlling ER ceramides and suppressing ceramide-induced apoptosis in cultured cells. SMSr-mediated ceramide homeostasis relies on the enzyme’s catalytic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ac4f3576363f27686570e426f95213
https://doi.org/10.1038/srep41290
https://doi.org/10.1038/srep41290
Autor:
Joachim Degen, Holger Jastrow, Klaus Willecke, Xian-Cheng Jiang, Katharina vom Dorp, René L. Jacobs, Andreas Bickert, Joost C. M. Holthuis, Dennis E. Vance, Matthijs Kol, Pentti Somerharju, Christina Ginkel, Elke Winterhager, Peter Dörmann
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 4, Pp 821-835 (2015)
Besides bulk amounts of SM, mammalian cells produce small quantities of the SM analog ceramide phosphoethanolamine (CPE). Little is known about the biological role of CPE or enzymes responsible for CPE production. Heterologous expression studies reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b10cc5d3bf00a719f836e5684ac1a9
http://hdl.handle.net/10138/162178
http://hdl.handle.net/10138/162178
