Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andreas Berghaus"'
Autor:
Martin Spoerk, Ioannis Koutsamanis, Josip Matić, Simone Eder, Carolina Patricia Alva Zúñiga, Johannes Poms, Jesús Alberto Afonso Urich, Raymar Andreína Lara García, Klaus Nickisch, Karin Eggenreich, Andreas Berghaus, Kathrin Reusch, Yorick Relle, Johannes Khinast, Amrit Paudel
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 588 (2020)
To avoid any type of cross-contamination, residue-free production equipment is of utmost importance in the pharmaceutical industry. The equipment cleaning for continuous processes such as hot melt extrusion (HME), which has recently gained popularity
Externí odkaz:
https://doaj.org/article/68264e93ced746988a89d9fb178a2e77
Autor:
Juan Almeida, Mariana Bezerra, Daniel Markl, Andreas Berghaus, Phil Borman, Walkiria Schlindwein
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 150 (2020)
A key principle of developing a new medicine is that quality should be built in, with a thorough understanding of the product and the manufacturing process supported by appropriate process controls. Quality by design principles that have been establi
Externí odkaz:
https://doaj.org/article/315bfc710dc343328cff4c783a54df0e
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 207 (2018)
Over recent years Twin-Screw-Extrusion (TSE) has been established as a platform technology for pharmaceutical manufacturing. Compared to other continuous operation, one of the major benefits of this method is the combination of several unit operation
Externí odkaz:
https://doaj.org/article/2c321d6a80504dc88ffb5f8c611860cd
Autor:
Walkiria Schlindwein, Mariana Bezerra, Juan Almeida, Andreas Berghaus, Martin Owen, Gordon Muirhead
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 166 (2018)
This paper displays the potential of an in-line PAT system for early phase product development during pharmaceutical continuous manufacturing following a Quality by Design (QbD) framework. Hot melt extrusion (HME) is used as continuous manufacturing
Externí odkaz:
https://doaj.org/article/9cf95b90675449ce9898f3e1fad700f1
Publikováno v:
Pharmaceutics, Vol 10, Iss 2, p 49 (2018)
In the framework of Quality-by-Design (QbD), the inline determination of process parameters or quality attributes of a product using sufficient process analytical technology (PAT) is a center piece for the establishment of continuous processes as a s
Externí odkaz:
https://doaj.org/article/7a55a90460284184aac0c63e02b32175
Publikováno v:
Pharmaceutical development and technology.
The poor solubility of a large number of active pharmaceutical ingredients (APIs) is a major challenge in pharmaceutical research. Therefore, the extrusion of amorphous solid dispersions (ASDs) is one promising approach to enhance the dissolution rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e208973d44a3ce9fa0a3c34ccb8da48c
https://pubmed.ncbi.nlm.nih.gov/36331240
https://pubmed.ncbi.nlm.nih.gov/36331240
Autor:
Andreas Berghaus, Maike Joester, Tim D. Lillotte, Robert F. Lammens, Benjamin Frindt, Karl G. Wagner
In this study, a novel approach was developed for determining the density of compacts using ultraviolet–visible spectrophotometry. The assumption within this context was that a change in density affects the corresponding color information of the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d65182a52ebfe09b142a045452da694
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00069859
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00069859
Autor:
Kathrin Reusch, Raymar Andreína Lara García, Jesús Alberto Afonso Urich, Carolina Patricia Alva Zúñiga, Johannes Khinast, Josip Matić, Amrit Paudel, Karin Eggenreich, Andreas Berghaus, Johannes Poms, Simone Eder, Martin Spoerk, Yorick Relle, Klaus Nickisch, Ioannis Koutsamanis
Publikováno v:
Pharmaceutics, Vol 12, Iss 588, p 588 (2020)
Pharmaceutics
Volume 12
Issue 6
Pharmaceutics
Volume 12
Issue 6
To avoid any type of cross-contamination, residue-free production equipment is of utmost importance in the pharmaceutical industry. The equipment cleaning for continuous processes such as hot melt extrusion (HME), which has recently gained popularity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb9d33b6e6b82f09d1b9698c7d62385
https://www.mdpi.com/1999-4923/12/6/588
https://www.mdpi.com/1999-4923/12/6/588
Publikováno v:
AAPS PharmSciTech
Chemical degradation of drug substances remains a major drawback of extrusion. Larger-scale extrusion equipment has advantages over smaller equipment due to deeper flight elements and added flexibility in terms of screw design, unit operations, and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2aebb562ffb6a7ab7bdc74a7f60367
https://doi.org/10.1208/s12249-018-1162-5
https://doi.org/10.1208/s12249-018-1162-5
Autor:
Phil J. Borman, Andreas Berghaus, Walkiria Schlindwein, Juan Almeida, Daniel Markl, Mariana Bezerra
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 12, Iss 2, p 150 (2020)
Volume 12
Issue 2
Pharmaceutics, Vol 12, Iss 2, p 150 (2020)
Volume 12
Issue 2
A key principle of developing a new medicine is that quality should be built in, with a thorough understanding of the product and the manufacturing process supported by appropriate process controls. Quality by design principles that have been establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e076b39f8710c81fcf763dccc8514e9d
https://pubmed.ncbi.nlm.nih.gov/32059445
https://pubmed.ncbi.nlm.nih.gov/32059445