Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Andreas Behren"'
Autor:
Tirta M. Djajawi, Lizzy Pijpers, Akash Srivaths, David Chisanga, Kok Fei Chan, Simon J. Hogg, Liam Neil, Sarahi Mendoza Rivera, Nenad Bartonicek, Sarah L. Ellis, Terry C.C. Lim Kam Sian, Pouya Faridi, Yang Liao, Bhupinder Pal, Andreas Behren, Wei Shi, Stephin J. Vervoort, Ricky W. Johnstone, Conor J. Kearney
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113831- (2024)
Summary: Cancer immunotherapies have demonstrated remarkable success; however, the majority of patients do not respond or develop resistance. Here, we conduct epigenetic gene-targeted CRISPR-Cas9 screens to identify epigenomic factors that limit CD8+
Externí odkaz:
https://doaj.org/article/f34b9312d8234fce939c7254165dac3d
Autor:
Emtiaz Ahmed, Karthik Balaji Shanmugasundaram, Junrong Li, Andreas Behren, Richard Lobb, Andreas Möller, Alain Wuethrich, Shuvashis Dey, Abu Ali Ibn Sina, Matt Trau
Publikováno v:
Advanced Sensor Research, Vol 2, Iss 12, Pp n/a-n/a (2023)
Abstract Tumor cells display heterogenous molecular signatures during the course of cancer and create distinct tumor cell subpopulations which challenge effective therapeutic decisions. Detection and monitoring of these heterogenous molecular events
Externí odkaz:
https://doaj.org/article/3e2292492920453e95bbb473b21549e4
Autor:
David Williams, Gabrielle Belz, Wei Shi, Anita Kumari, Andreas Behren, Maxine Smith, Marina Yakou, Sonia Ghilas, Kelly Tran, Yang Liao, Shoukat Afshar-Sterle, Kevin Schmid, Christine Dijkstra, Chantelle Inguanti, Simone Ostrouska, Jordan Wilcox, Pavitha Parathan, Amr Allam, Hai-Hui Xue, John Mariadason, Grant Drummond, Roland Ruscher, Bhupinder Pal, Matthias Ernst, Dinesh Raghu, Lisa A Mielke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/53e2c7996d52481f9160ae107e1bb5fa
Autor:
Andreas Behren, Simone Ostrouska, Kok Fei Chan, Tianming Li, Andrew Hammet, Marc Rigau, Adam P Uldrich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/ea725daa2d044bfe8c98b649987040ba
Publikováno v:
Exploration of Immunology, Vol 2, Iss 3, Pp 383-392 (2022)
Conventional immunohistochemistry methods though once fundamental for the individual staining of cell markers, have now been superseded by multispectral immunohistochemistry (mIHC). mIHC enables simultaneous detection of multiple cell markers in situ
Externí odkaz:
https://doaj.org/article/7f19be1e55384169b3b2b531865d69ca
Autor:
Luke T. Quigley, Lokman Pang, Elnaz Tavancheh, Matthias Ernst, Andreas Behren, Jennifer Huynh, Jessica Da Gama Duarte
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101961- (2023)
Summary: Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates that can develop within or adjacent to tumors, but protocols that can accurately identify and characterize TLSs are lacking. Here, we present a protocol for the in situ inte
Externí odkaz:
https://doaj.org/article/9f4f84841d1c495c94cac67d5881df4f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A growing number of studies have shown that γδ T cells play a pivotal role in mediating the clearance of tumors and pathogen-infected cells with their potent cytotoxic, cytolytic, and unique immune-modulating functions. Unlike the more abundant α
Externí odkaz:
https://doaj.org/article/92773ccc2b70407a9198b88f5b7f27a0
Autor:
Junrong Li, Alain Wuethrich, Abu A. I. Sina, Han-Hao Cheng, Yuling Wang, Andreas Behren, Paul N. Mainwaring, Matt Trau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
There is a clinical need to monitor immune-related toxicities of immune checkpoint blockade therapy. Here, the authors develop a digital SERS platform for multiplexed single cytokine counting to track immune-toxicities and demonstrate the ability to
Externí odkaz:
https://doaj.org/article/ad3a6c015bda45c3bc4d1c2fcc075fea
Autor:
Linda Mileshkin, Ben Markman, Oliver Klein, Damien Kee, Jonathan Cebon, Andreas Behren, Matteo Carlino, Bo Gao, Jessica da Gama Duarte, Luke Quigley, Louise Jackett, Richelle Linklater, Andrew Strickland, Clare Scott, Jodie Palmer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/6766e0f0fbac49fbb8002327f10273b3
Autor:
Sagun Parakh, Ashan Musafer, Sabrina Paessler, Tom Witkowski, Connie S. N. Li Wai Suen, Candani S. A. Tutuka, Matteo S. Carlino, Alexander M. Menzies, Richard A. Scolyer, Jonathan Cebon, Alexander Dobrovic, Georgina V. Long, Oliver Klein, Andreas Behren
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A significant number of patients (pts) with metastatic melanoma do not respond to anti-programmed cell death 1 (PD1) therapies. Identifying predictive biomarkers therefore remains an urgent need. We retrospectively analyzed plasma DNA of pts with adv
Externí odkaz:
https://doaj.org/article/60fdb249cd3241e8afe688013434c093