Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Andreas Aufschnaiter"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Externí odkaz:
https://doaj.org/article/a99b7e41cd714162a9529e57fdbe7b26
Autor:
Lukas Habernig, Filomena Broeskamp, Andreas Aufschnaiter, Jutta Diessl, Carlotta Peselj, Elisabeth Urbauer, Tobias Eisenberg, Ana de Ory, Sabrina Büttner
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009911 (2021)
The capacity of a cell to maintain proteostasis progressively declines during aging. Virtually all age-associated neurodegenerative disorders associated with aggregation of neurotoxic proteins are linked to defects in the cellular proteostasis networ
Externí odkaz:
https://doaj.org/article/3275e960d02c424789ab4ab1a2d49e6a
Autor:
Mahsa Ebrahimi, Lukas Habernig, Filomena Broeskamp, Andreas Aufschnaiter, Jutta Diessl, Isabel Atienza, Steffen Matz, Felix A. Ruiz, Sabrina Büttner
Publikováno v:
Cells, Vol 10, Iss 11, p 3161 (2021)
Nutrient limitation results in an activation of autophagy in organisms ranging from yeast, nematodes and flies to mammals. Several evolutionary conserved nutrient-sensing kinases are critical for efficient adaptation of yeast cells to glucose, nitrog
Externí odkaz:
https://doaj.org/article/66272d53b3b0473b863a7fdb23b8b284
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 11, Pp 1776-1779 (2017)
Cellular homeostasis requires a tightly controlled balance between protein synthesis, folding and degradation. Especially long-lived, post-mitotic cells such as neurons depend on an efficient proteostasis system to maintain cellular health over decad
Externí odkaz:
https://doaj.org/article/2a454300ef664140ba5637dc1e20b622
Autor:
Christine Leibiger, Jana Deisel, Andreas Aufschnaiter, Stefanie Ambros, Maria Tereshchenko, Bert M. Verheijen, Sabrina Büttner, Ralf J. Braun
Publikováno v:
Microbial Cell, Vol 5, Iss 4, Pp 212-214 (2018)
The accumulation of protein aggregates in neurons is a typical pathological hallmark of the motor neuron disease amyotrophic lateral sclerosis (ALS) and of frontotemporal dementia (FTD). In many cases, these aggregates are composed of the 43 kDa TAR
Externí odkaz:
https://doaj.org/article/0fc3323040ed48058962ad0a9d04384b
Publikováno v:
Cells, Vol 9, Iss 5, p 1184 (2020)
In all eukaryotic cells, intracellular organization and spatial separation of incompatible biochemical processes is established by individual cellular subcompartments in form of membrane-bound organelles. Virtually all of these organelles are physica
Externí odkaz:
https://doaj.org/article/ba5143314821442ba4479a9b9772ee68
Autor:
Andreas Aufschnaiter, Verena Kohler, Shaden Khalifa, Aida Abd El-Wahed, Ming Du, Hesham El-Seedi, Sabrina Büttner
Publikováno v:
Toxins, Vol 12, Iss 2, p 66 (2020)
Natural products represent important sources for the discovery and design of novel drugs. Bee venom and its isolated components have been intensively studied with respect to their potential to counteract or ameliorate diverse human diseases. Despite
Externí odkaz:
https://doaj.org/article/1207732293cf4b37862ac59e9069aa86
Autor:
Andreas Aufschnaiter, Verena Kohler, Corvin Walter, Sergi Tosal-Castano, Lukas Habernig, Heimo Wolinski, Walter Keller, F.-Nora Vögtle, Sabrina Büttner
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Mitochondrial dysfunction is a prominent trait of cellular decline during aging and intimately linked to neuronal degeneration during Parkinson’s disease (PD). Various proteins associated with PD have been shown to differentially impact mitochondri
Externí odkaz:
https://doaj.org/article/73923da2c0f14c67afcab056c1eac789
Autor:
Andreas Aufschnaiter, Lukas Habernig, Verena Kohler, Jutta Diessl, Didac Carmona-Gutierrez, Tobias Eisenberg, Walter Keller, Sabrina Büttner
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
The degeneration of dopaminergic neurons during Parkinson’s disease (PD) is intimately linked to malfunction of α-synuclein (αSyn), the main component of the proteinaceous intracellular inclusions characteristic for this pathology. The cytotoxici
Externí odkaz:
https://doaj.org/article/243725b1d8834437a3ae45936005a435
Autor:
Andreas Aufschnaiter, Martin Ott
Publikováno v:
BIOspektrum. 28:366-369
A key function of mitochondria consists of energy conversion, performed with the help of the respiratory chain and the ATP synthase. Biogenesis of these essential molecular machines requires expression of nuclear and mitochondrially encoded genes. We