Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Andreas A. Verras"'
Publikováno v:
Clinical Chemistry. 41:1637-1643
We studied a new commercially available thyrotropin (TSH) assay, the AquaLite Bioluminescence TSH-Immunoassay (SeaLite Inc.). This assay has a detection limit of 0.005 mIU/L and a functional sensitivity of 0.017 mIU/L and meets the requirements of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74927985f6524b666c1401e3f6e755b9
https://doi.org/10.1093/clinchem/41.11.1637
https://doi.org/10.1093/clinchem/41.11.1637
Autor:
Mak VW; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States., Patel AM; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States., Yen R; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States., Hanisak J; Discovery Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Lim YH; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States., Bao J; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States.; Ionova Life Science, Shenzhen 518122, Guangdong, China., Zheng R; IDSU, Wuxi AppTec Co., Ltd, Shanghai 200131, China., Seganish WM; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States., Yu Y; Discovery Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Healy DR; Discovery Biology, Merck & Co., Inc., Boston, Massachusetts 02115, United States., Ogawa A; Quantitative Biosciences, Merck & Co., Inc., South San Francisco, California 94080, United States., Ren Z; Quantitative Biosciences, Merck & Co., Inc., South San Francisco, California 94080, United States., Soriano A; Mass Spectrometry and Biophysics, Computation and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Ermakov GP; PPDM Discovery Bioanalytics, Merck & Co., Inc., South San Francisco, California 94080, United States., Beaumont M; PPDM Discovery Bioanalytics, Merck & Co., Inc., South San Francisco, California 94080, United States., Metwally E; Computational and Structural Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States., Cheng AC; Computational and Structural Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States., Verras A; Schrodinger Inc., 120 West 45th Street, 17th Floor, New York, New York 10036-4041, United States.; Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Fischmann T; Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Zebisch M; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Silvestre HL; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., McEwan PA; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Barker J; Evotec (UK) Ltd, 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K., Rearden P; DMPK, Recursion Pharmaceuticals, Salt Lake City, Utah 84101, United States.; PPDM, Merck & Co., Inc., South San Francisco, California 94080, United States., Greshock TJ; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Aug 11; Vol. 65 (15), pp. 10318-10340. Date of Electronic Publication: 2022 Jul 25.
Autor:
Lynch EM; Department of Biochemistry, University of Washington, Seattle, WA 98195., DiMattia MA; Schrödinger, New York, NY 10036., Albanese S; Schrödinger, New York, NY 10036., van Zundert GCP; Schrödinger, New York, NY 10036., Hansen JM; Department of Biochemistry, University of Washington, Seattle, WA 98195., Quispe JD; Department of Biochemistry, University of Washington, Seattle, WA 98195., Kennedy MA; Department of Biochemistry, University of Washington, Seattle, WA 98195., Verras A; Schrödinger, New York, NY 10036., Borrelli K; Schrödinger, New York, NY 10036., Toms AV; Nimbus Therapeutics, Cambridge, MA 02139., Kaila N; Nimbus Therapeutics, Cambridge, MA 02139., Kreutter KD; Nimbus Therapeutics, Cambridge, MA 02139., McElwee JJ; Nimbus Therapeutics, Cambridge, MA 02139., Kollman JM; Department of Biochemistry, University of Washington, Seattle, WA 98195; jkoll@uw.edu.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Oct 05; Vol. 118 (40).
Autor:
Hanisak J; Discovery Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Soriano A; Mass Spectrometry and Biophysics, Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Adam GC; Quantitative Biosciences, Merck & Co., Inc, West Point, Pennsylvania 19486, United States., Basso A; Mass Spectrometry and Biophysics, Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Bauman D; Discovery Biology, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Bell D; Mass Spectrometry and Biophysics, Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Frank E; Mass Spectrometry and Biophysics, Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., O'Donnell G; Quantitative Biosciences, Merck & Co., Inc, West Point, Pennsylvania 19486, United States., Tawa P; Mass Spectrometry and Biophysics, Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Verras A; Computational and Structural Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Yu Y; Discovery Chemistry, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States., Zhang L; Biologics Analytical Research and Development, Merck & Co., Inc., Kenilworth, New Jersey, 07033 United States., Seganish WM; Discovery Chemistry, Merck & Co., Inc., South San Francisco, California 94080, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Jul 16; Vol. 12 (8), pp. 1275-1282. Date of Electronic Publication: 2021 Jul 16 (Print Publication: 2021).
Autor:
Bosc N; European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, CB10 1SD, Hinxton, Cambridge, United Kingdom. nbosc@ebi.ac.uk., Felix E; European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, CB10 1SD, Hinxton, Cambridge, United Kingdom., Arcila R; European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, CB10 1SD, Hinxton, Cambridge, United Kingdom., Mendez D; European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, CB10 1SD, Hinxton, Cambridge, United Kingdom., Saunders MR; Department of Molecular Design, Data and Computational Sciences, GlaxoSmithKline, Gunnels Wood Road, Hertfordshire, SG1 2NY, Stevenage, UK., Green DVS; Department of Molecular Design, Data and Computational Sciences, GlaxoSmithKline, Gunnels Wood Road, Hertfordshire, SG1 2NY, Stevenage, UK., Ochoada J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Tennessee, 38105, Memphis, USA., Shelat AA; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Tennessee, 38105, Memphis, USA., Martin EJ; Novartis Institute for Biomedical Research, 5300 Chiron Way, California, 94608- 2916, Emeryville, USA., Iyer P; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Engkvist O; Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Verras A; Schrodinger Inc, 120 West 45th Street, 10036-4041, New York, NY, USA., Duffy J; Medicines for Malaria Ventures Discovery, 1215, Geneva, Switzerland., Burrows J; Medicines for Malaria Ventures Discovery, 1215, Geneva, Switzerland., Gardner JMF; AMG Consultants Ltd, Discovery Park House, Discovery Park, Ramsgate Road, CT13 9ND, Sandwich, Kent, UK., Leach AR; European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, CB10 1SD, Hinxton, Cambridge, United Kingdom. arl@ebi.ac.uk.
Publikováno v:
Journal of cheminformatics [J Cheminform] 2021 Feb 22; Vol. 13 (1), pp. 13. Date of Electronic Publication: 2021 Feb 22.
Autor:
Liu K; Merck & Co., Inc., Rahway, NJ 07065, United States., Kurukulasuriya R; Merck & Co., Inc., Rahway, NJ 07065, United States., Dykstra K; Merck & Co., Inc., Rahway, NJ 07065, United States., DiMichelle L; Merck & Co., Inc., Rahway, NJ 07065, United States., Liu J; Merck & Co., Inc., Rahway, NJ 07065, United States., Vachal P; Merck & Co., Inc., Rahway, NJ 07065, United States., Ogawa A; Merck & Co., Inc., Rahway, NJ 07065, United States., DeVita RJ; Merck & Co., Inc., Rahway, NJ 07065, United States., Shen DM; Merck & Co., Inc., Rahway, NJ 07065, United States., Tan Q; Merck & Co., Inc., Rahway, NJ 07065, United States., Chen Y; Merck & Co., Inc., Rahway, NJ 07065, United States., Gauthier D; Merck & Co., Inc., Rahway, NJ 07065, United States., Verras A; Merck & Co., Inc., Rahway, NJ 07065, United States., Crespo A; Merck & Co., Inc., Rahway, NJ 07065, United States., Zamlynny B; Merck & Co., Inc., Rahway, NJ 07065, United States., Madwed J; Merck & Co., Inc., Rahway, NJ 07065, United States., Hoek M; Merck & Co., Inc., Rahway, NJ 07065, United States., Bateman T; Merck & Co., Inc., Rahway, NJ 07065, United States., Yang YF; University of California at Los Angeles, Department of Chemistry and Biochemistry, Los Angeles, CA 90095, United States., Houk KN; University of California at Los Angeles, Department of Chemistry and Biochemistry, Los Angeles, CA 90095, United States., Krska S; Merck & Co., Inc., Rahway, NJ 07065, United States., Cernak T; Merck & Co., Inc., Rahway, NJ 07065, United States. Electronic address: tcernak@med.umich.edu.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Jul 15; Vol. 29 (14), pp. 1854-1858. Date of Electronic Publication: 2019 Apr 15.
Autor:
Yu Y; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States. Electronic address: yang_yu@merck.com., Wu Z; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Shi ZC; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., He S; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Lai Z; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Cernak TA; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Vachal P; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Liu M; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Liu J; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Hong Q; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Jian T; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Guiadeen D; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Krikorian A; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Sperbeck DM; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Verras A; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Sonatore LM; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Murphy BA; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Wiltsie J; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Chung CC; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Gorski JN; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Liu J; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Xiao J; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Wolff M; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Tong SX; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Madeira M; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Karanam BV; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Shen DM; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Balkovec JM; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., De Vita RJ; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Pinto S; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States., Nargund RP; Discovery and Preclinical Sciences, Merck & Co. Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, United States.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Jun 01; Vol. 29 (11), pp. 1380-1385. Date of Electronic Publication: 2019 Mar 27.
Autor:
He S; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States. Electronic address: shuwen@kallyope.com., Lai Z; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Hong Q; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Shang J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Reibarkh M; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Kuethe JT; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Liu J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Guiadeen D; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Krikorian AD; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Cernak TA; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Dykstra KD; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Sperbeck DM; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Wu Z; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Yu Y; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Yang GX; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Jian T; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Verras A; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Sonatore LM; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Wiltsie J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Chung CC; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Murphy BA; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Gorski JN; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Liu J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Xiao J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Wolff M; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Tong SX; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Madeira M; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Karanam BV; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Shen DM; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Balkovec JM; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Pinto S; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., Nargund RP; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States., DeVita RJ; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 May 15; Vol. 29 (10), pp. 1182-1186. Date of Electronic Publication: 2019 Mar 21.
Autor:
Fradera X; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, MA, 02215, USA. xavier.fradera@merck.com., Verras A; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA. Andreas.verras@merck.com., Hu Y; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Wang D; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA, 19486, USA., Wang H; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Fells JI; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Armacost KA; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA, 19486, USA., Crespo A; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Sherborne B; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Wang H; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Peng Z; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Gao YD; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA.
Publikováno v:
Journal of computer-aided molecular design [J Comput Aided Mol Des] 2018 Jan; Vol. 32 (1), pp. 113-127. Date of Electronic Publication: 2017 Sep 14.
Autor:
Gao YD; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA. yingduo_gao@merck.com., Hu Y; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA. yuan.hu@merck.com., Crespo A; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA. alejandro_crespo@merck.com., Wang D; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA, 19486, USA., Armacost KA; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA, 19486, USA., Fells JI; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Fradera X; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, MA, 02215, USA., Wang H; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Wang H; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Sherborne B; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Verras A; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA., Peng Z; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033-1310, USA.
Publikováno v:
Journal of computer-aided molecular design [J Comput Aided Mol Des] 2018 Jan; Vol. 32 (1), pp. 129-142. Date of Electronic Publication: 2017 Oct 06.