Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Andreas Wack"'
Autor:
Stefania Crotta, Matteo Villa, Jack Major, Katja Finsterbusch, Miriam Llorian, Peter Carmeliet, Joerg Buescher, Andreas Wack
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Airway epithelial repair, a key process in the recovery from lung injury, requires a metabolic shift from glycolysis to fatty acid oxidation (FAO). Pharmacological FAO promotion enhances epithelial differentiation, suggesting new therapeutic options.
Externí odkaz:
https://doaj.org/article/0f17e6d006a2459fafee9429aa641663
Autor:
Mariana Pereira da Costa, Carlos M. Minutti, Cécile Piot, Evangelos Giampazolias, Ana Cardoso, Mar Cabeza-Cabrerizo, Neil C. Rogers, Marta Lebrusant-Fernandez, Chrysante S. Iliakis, Andreas Wack, Caetano Reis e Sousa
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112881- (2023)
Summary: Conventional dendritic cells (cDCs) are found in most tissues and play a key role in initiation of immunity. cDCs require constant replenishment from progenitors called pre-cDCs that develop in the bone marrow (BM) and enter the blood circul
Externí odkaz:
https://doaj.org/article/5ebd2a907dff4b73a3ad94ba92aaae7c
Autor:
Peter A C Wing, Maria Prange-Barczynska, Amy Cross, Stefania Crotta, Claudia Orbegozo Rubio, Xiaotong Cheng, James M Harris, Xiaodong Zhuang, Rachel L Johnson, Kathryn A Ryan, Yper Hall, Miles W Carroll, Fadi Issa, Peter Balfe, Andreas Wack, Tammie Bishop, Francisco J Salguero, Jane A McKeating
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010807 (2022)
Understanding the host pathways that define susceptibility to Severe-acute-respiratory-syndrome-coronavirus-2 (SARS-CoV-2) infection and disease are essential for the design of new therapies. Oxygen levels in the microenvironment define the transcrip
Externí odkaz:
https://doaj.org/article/3c410b7e7d0e4ff392b4c3a2e70b9525
Autor:
Jacob Thyrsted, Jacob Storgaard, Julia Blay-Cadanet, Alexander Heinz, Anne Laugaard Thielke, Stefania Crotta, Frank de Paoli, David Olagnier, Andreas Wack, Karsten Hiller, Anne Louise Hansen, Christian Kanstrup Holm
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103300- (2021)
Summary: Pathogenic viruses induce metabolic changes in host cells to secure the availability of biomolecules and energy to propagate. Influenza A virus (IAV) and severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) both infect the human air
Externí odkaz:
https://doaj.org/article/4026fa2356d24d3aa8b17fca2a42d3f0
Autor:
Jamie Aranda, Goundappa K Balasubramani, Ritu Banerjee, Behin Barahimi, Laura A. Binari, David M. Brooks, Anna Burgner, Alexander De Castro-Abeger, Matthew Chinn, Amparo de la Peña, Ally Esch, Mark E. Garcia, Ben Geoffrey A.S., Pravin George, Karen E. Giles, Aarthi Goverdhan, Daniel Griffin, Sylvia Groth, Madihah Hepburn, Nancy Jacobson, Sarah Kim, Charles A. Knirsch, Srinivasan Krishnaswami, Sriram Krishnaswami, Pooja Lal, Susan M. Lopata, Subramani Mani, Natalie N. McCall, William M. McDonald, Sujatha S. Menon, Cullen P. Moran, Sivakumar Nagaraju, Christopher Newey, Mary Patricia Nowalk, Dhyanesh A. Patel, Amelie Pham, Krishna Ramakrishnamenon Prasad, Sathishkumar Ramalingam, John C. Ray, Mythily Srinivasan, Amit K. Srivastava, Jennifer L. Thompson, Thankam Thyvalikakath, Michael F. Vaezi, Andreas Wack, Robert S. Wallis, Charles B. Nemeroff, Jörn-Hendrik Weitkamp
Publikováno v:
Textbook of SARS-CoV-2 and COVID-19 ISBN: 9780323875394
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd94c6282691bb93435208c78346e4ca
https://doi.org/10.1016/b978-0-323-87539-4.00029-4
https://doi.org/10.1016/b978-0-323-87539-4.00029-4
Publikováno v:
Textbook of SARS-CoV-2 and COVID-19 ISBN: 9780323875394
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f6a4d6beeb86c4daffee2a83a326f70
https://doi.org/10.1016/b978-0-323-87539-4.00003-8
https://doi.org/10.1016/b978-0-323-87539-4.00003-8
Autor:
Akul Singhania, Christine M. Graham, Leona Gabryšová, Lúcia Moreira-Teixeira, Evangelos Stavropoulos, Jonathan M. Pitt, Probir Chakravarty, Annika Warnatsch, William J. Branchett, Laura Conejero, Jing-Wen Lin, Sophia Davidson, Mark S. Wilson, Gregory Bancroft, Jean Langhorne, Eva Frickel, Abdul K. Sesay, Simon L. Priestnall, Eleanor Herbert, Marianna Ioannou, Qian Wang, Ian R. Humphreys, Jonathan Dodd, Peter J. M. Openshaw, Katrin D. Mayer-Barber, Dragana Jankovic, Alan Sher, Clare M. Lloyd, Nicole Baldwin, Damien Chaussabel, Venizelos Papayannopoulos, Andreas Wack, Jacques F. Banchereau, Virginia M. Pascual, Anne O’Garra
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
The authors present an extensive profile of host transcriptional respones to a diverse group of pathogens and allergens. In doing so, they identify TH1, type I IFN, TH17, and TH2 responses, that underlie each immune response in both the blood and lun
Externí odkaz:
https://doaj.org/article/2de9148c41624ebdb261719be7a52d90
Autor:
Daniel Schnepf, Pedro Hernandez, Tanel Mahlakõiv, Stefania Crotta, Meagan E Sullender, Stefan T Peterson, Annette Ohnemus, Camille Michiels, Ian Gentle, Laure Dumoutier, Celso A Reis, Andreas Diefenbach, Andreas Wack, Megan T Baldridge, Peter Staeheli
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0247738 (2021)
The commensal microbiota regulates susceptibility to enteric pathogens by fine-tuning mucosal innate immune responses, but how susceptibility to enteric viruses is shaped by the microbiota remains incompletely understood. Past reports have indicated
Externí odkaz:
https://doaj.org/article/d68b02450db24632b3ba2774fe30dfac
Autor:
Nikaïa Smith, Nicolas Pietrancosta, Sophia Davidson, Jacques Dutrieux, Lise Chauveau, Pasquale Cutolo, Michel Dy, Daniel Scott-Algara, Bénédicte Manoury, Onofrio Zirafi, Isabelle McCort-Tranchepain, Thierry Durroux, Françoise Bachelerie, Olivier Schwartz, Jan Münch, Andreas Wack, Sébastien Nisole, Jean-Philippe Herbeuval
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.
Externí odkaz:
https://doaj.org/article/4dcfeb35184e41db9075187f20ab2655
Autor:
Konrad C. Bradley, Katja Finsterbusch, Daniel Schnepf, Stefania Crotta, Miriam Llorian, Sophia Davidson, Serge Y. Fuchs, Peter Staeheli, Andreas Wack
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 245-256.e4 (2019)
Summary: Type I interferon (IFNα/β) pathways are fine-tuned to elicit antiviral protection while minimizing immunopathology; however, the initiating stimuli, target tissues, and underlying mechanisms are unclear. Using models of physiological and d
Externí odkaz:
https://doaj.org/article/b38812bc603440c1ac47e05b4631b8c3