Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Andreas Heitger"'
Autor:
Friedrich Erhart, Manuel Lau, Sarah Ahmadi-Erber, Markus A. Hoelzl, Barbara Dillinger, Alexander M. Dohnal, Andreas Heitger, Stephan Ladisch, Dietmar Fuchs, Birgit Juergens
Publikováno v:
Cellular Immunology. 325:33-40
Gangliosides shed by tumors into their microenvironment (TME) are immunoinhibitory. Interferon-γ (IFN-γ) may boost antitumor immune responses. Thus we wondered whether IFN-γ would counteract tumor ganglioside-mediated immune suppression. To test t
Publikováno v:
Transplantation. 98:1158-1164
BACKGROUND CTLA-4 immunoglobulin fusion proteins (CTLA4-Ig) suppress immune reactions by blocking the T-cell costimulatory CD28-CD80-86 pathway and are used in clinical trials for diseases featuring exaggerated T-cell reactivity including autoimmune
Autor:
Margit Lanzinger, Dietmar Fuchs, Barbara Dillinger, and Andreas Heitger, Ursula Hainz, Julia Raberger, Birgit Jürgens
Publikováno v:
European Journal of Immunology. 42:1117-1128
Prostaglandin E2 (PGE2), an abundantly produced lipid messenger in mammalian organisms, has been attributed to possess potent albeit ambivalent immunological functions. Recently, PGE2 has been reported to stimulate the commonly believed immunosuppres
Autor:
Olaf Bodamer, Andreas Heitger, Chike B. Item, Markus G. Seidel, Edith Schober, Petra Zeitlhofer, Oskar A. Haas, Birgit Rami, Wolf Dietrich Huber
Publikováno v:
European Journal of Endocrinology. 167:131-134
CLTA4 is relevant for FOXP3(+)Treg cells, and the link between skewed X chromosome inactivation (XCI) and autoimmunity is recognized. The observation of immune dysregulation polyendocrinopathy enteropathy X-linked syndrome and multiorgan endocrine au
Publikováno v:
Blood. 114:3235-3243
The role of the tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase (IDO) in down-regulating human alloresponses has recently been controversially debated. We here demonstrate that human monocyte-derived dendritic cells (mDCs) can be endowed w
Publikováno v:
Current Drug Metabolism. 8:267-272
Hematopoietic stem cell transplantation (HSCT) is complicated by unwelcome side-effects that arise on the basis of an altered immune system. Infectious complications and alloreactive T-cell responses trigger a process of ongoing immune activation and
Autor:
Dávid Héja, Sabine Heitzeneder, Elisabeth Förster-Waldl, Anita Lawitschka, Markus G. Seidel, M Hölzl, Petra Zeitlhofer, Oskar A. Haas, E Nowak, Ulrike Pötschger, Andreas Heitger, Susanne Matthes-Martin
Publikováno v:
Bone marrow transplantation. 50(8)
Mannan-binding lectin deficiency attenuates acute GvHD in pediatric hematopoietic stem cell transplantation
Publikováno v:
Scopus-Elsevier
Autor:
Gottfried Dohr, Alexei Gratchev, Ursula Hainz, Reinhold Wintersteiger, Peter Sedlmayr, Dagmar Azzola, Andreas Heitger, Osamu Takikawa, Sergij Goerdt, Kristijan Cupurdija
Publikováno v:
American Journal of Reproductive Immunology. 51:117-122
Problem: Depending on the type of their activation, macrophages may promote TH1- or TH2-type of immune responses. To date, not much is known about the activation phenotype of decidua macrophages, which – together with NK cells – constitute the ma
Autor:
Sheila A. Caldwell, Stephan Ladisch, Barbara J. Taylor, Andreas Heitger, Yihui Liu, Weiping Shen
Publikováno v:
The Journal of Immunology. 171:1676-1683
Gangliosides shed by tumor cells exert potent inhibitory effects on cellular immune responses. Here we have studied ganglioside inhibition of APC function. When human monocytes were preincubated in 50 μM highly purified ganglioside GD1a, pulsed with