Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Andreas, Zoephel"'
Autor:
Nina Kerres, Steffen Steurer, Stefanie Schlager, Gerd Bader, Helmut Berger, Maureen Caligiuri, Christian Dank, John R. Engen, Peter Ettmayer, Bernhard Fischerauer, Gerlinde Flotzinger, Daniel Gerlach, Thomas Gerstberger, Teresa Gmaschitz, Peter Greb, Bingsong Han, Elizabeth Heyes, Roxana E. Iacob, Dirk Kessler, Heike Kölle, Lyne Lamarre, David R. Lancia, Simon Lucas, Moriz Mayer, Katharina Mayr, Nikolai Mischerikow, Katja Mück, Christoph Peinsipp, Oliver Petermann, Ulrich Reiser, Dorothea Rudolph, Klaus Rumpel, Carina Salomon, Dirk Scharn, Renate Schnitzer, Andreas Schrenk, Norbert Schweifer, Diane Thompson, Elisabeth Traxler, Roland Varecka, Tilman Voss, Alexander Weiss-Puxbaum, Sandra Winkler, Xiaozhang Zheng, Andreas Zoephel, Norbert Kraut, Darryl McConnell, Mark Pearson, Manfred Koegl
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2860-2875 (2017)
The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Disruption of its interaction with transcriptional repressors interferes with the oncogenic effects of BCL6. We
Externí odkaz:
https://doaj.org/article/43ac770ae3294c078849cf3143253f8a
Autor:
Jürgen Moll, Natarajan Muthusamy, Norbert Kraut, Darryl B. McConnell, Mark Pearson, Segundo Gonzalez, Peter Ettmayer, Sumithira Vasu, Swagata Goswami, Girish Rajgolikar, Michael P. Sanderson, Thomas Gerstberger, Renate Schnitzer, Andreas Zoephel, Heribert Arnhof, Dirk Scharn, Jark Böttcher, Seila Lorenzo-Herrero, Marc Kerenyi, Sebastian Carotta, Maria A. Impagnatiello, Harald Engelhardt, Rajeswaran Mani, Marco H. Hofmann
Supplementary Data including Table S1-Table S5 and Figure S1 - Figure S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d553495bd4441df245e0ecc2903f83f
https://doi.org/10.1158/1535-7163.22520835
https://doi.org/10.1158/1535-7163.22520835
Autor:
Günther R. Adolf, Jens Quant, Norbert Kraut, Guido Boehmelt, Pilar Garin-Chesa, Ulrich Reiser, Matthias Treu, Andreas Zoephel, Gerd Bader, Flavio Solca, Irene C. Waizenegger, Ulrike Tontsch-Grunt, Christian Haslinger, Eva Strauss, Rosa Baumgartinger, Dorothea Rudolph, Christoph Baumann, Stephan K. Zahn, Ulrich Gürtler, Patrizia Sini
Chemical structure of BI 811283: 2,3-diamino-pyrimidine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b569a67ee6db1fdbb4b9b9898d09fa
https://doi.org/10.1158/1535-7163.22503072
https://doi.org/10.1158/1535-7163.22503072
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
Supplementary Data, Table S1, S3, S6, S8, S10-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b265e4961eac4720f5366a19b7c1c2
https://doi.org/10.1158/2159-8290.22535216
https://doi.org/10.1158/2159-8290.22535216
Autor:
Günther R. Adolf, Jens Quant, Norbert Kraut, Guido Boehmelt, Pilar Garin-Chesa, Ulrich Reiser, Matthias Treu, Andreas Zoephel, Gerd Bader, Flavio Solca, Irene C. Waizenegger, Ulrike Tontsch-Grunt, Christian Haslinger, Eva Strauss, Rosa Baumgartinger, Dorothea Rudolph, Christoph Baumann, Stephan K. Zahn, Ulrich Gürtler, Patrizia Sini
Supplementary Table S1: Statistics of data collection and processing of AuroraB/INCENP in complex with BI 847325; Supplementary Table S2: Statistics of data collection and processing of MEK1 in complex with BI 847325; Supplementary Table S3: Statisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a674f9a24129289384fc2594456c5203
https://doi.org/10.1158/1535-7163.22503057
https://doi.org/10.1158/1535-7163.22503057
Autor:
Günther R. Adolf, Jens Quant, Norbert Kraut, Guido Boehmelt, Pilar Garin-Chesa, Ulrich Reiser, Matthias Treu, Andreas Zoephel, Gerd Bader, Flavio Solca, Irene C. Waizenegger, Ulrike Tontsch-Grunt, Christian Haslinger, Eva Strauss, Rosa Baumgartinger, Dorothea Rudolph, Christoph Baumann, Stephan K. Zahn, Ulrich Gürtler, Patrizia Sini
(A), MEK1 and phospho-MEK1/2; (B) ERK1/2 and phospho-ERK1/2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364401e0cf33e13f4ddf75ae3b69dd1f
https://doi.org/10.1158/1535-7163.22503066.v1
https://doi.org/10.1158/1535-7163.22503066.v1
Autor:
Norbert Kraut, Darryl B. McConnell, Mark Pearson, Timothy P. Heffernan, Mark Petronczki, Jurgen Moll, Rachel L. Mendes, Jonathan C. O'Connell, Christopher P. Vellano, Simone Lieb, Katharina Schipany, Franziska Schachinger, Nikolai Pototschnig, Jark Böttcher, Jessica L. Teh, Szu-Chin Fu, Andreas Zoephel, Tobias Wunberg, Christiane Kofink, Thomas Gerstberger, Peter Ettmayer, Dana-Adriana Botesteanu, Klaus Rumpel, Heribert Arnhof, Francesca Trapani, Dirk Kessler, Michael P. Sanderson, Joseph R. Marszalek, Daniel Gerlach, Fabio Savarese, Juergen Ramharter, Michael Gmachl, Marco H. Hofmann
KRAS is the most frequently mutated driver of pancreatic, colorectal, and non–small cell lung cancers. Direct KRAS blockade has proved challenging, and inhibition of a key downstream effector pathway, the RAF–MEK–ERK cascade, has shown limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4207250379f0cc7e1fcd4e873b0d65cb
https://doi.org/10.1158/2159-8290.c.6547790.v1
https://doi.org/10.1158/2159-8290.c.6547790.v1
Autor:
Günther R. Adolf, Jens Quant, Norbert Kraut, Guido Boehmelt, Pilar Garin-Chesa, Ulrich Reiser, Matthias Treu, Andreas Zoephel, Gerd Bader, Flavio Solca, Irene C. Waizenegger, Ulrike Tontsch-Grunt, Christian Haslinger, Eva Strauss, Rosa Baumgartinger, Dorothea Rudolph, Christoph Baumann, Stephan K. Zahn, Ulrich Gürtler, Patrizia Sini
(A), MEK1 and phospho-MEK1/2; (B) ERK1/2 and phospho-ERK1/2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea465e8bb386c7526ee890a39c10857
https://doi.org/10.1158/1535-7163.22503069.v1
https://doi.org/10.1158/1535-7163.22503069.v1
Autor:
Jürgen Moll, Natarajan Muthusamy, Norbert Kraut, Darryl B. McConnell, Mark Pearson, Segundo Gonzalez, Peter Ettmayer, Sumithira Vasu, Swagata Goswami, Girish Rajgolikar, Michael P. Sanderson, Thomas Gerstberger, Renate Schnitzer, Andreas Zoephel, Heribert Arnhof, Dirk Scharn, Jark Böttcher, Seila Lorenzo-Herrero, Marc Kerenyi, Sebastian Carotta, Maria A. Impagnatiello, Harald Engelhardt, Rajeswaran Mani, Marco H. Hofmann
Natural killer (NK) cells play a pivotal role in controlling cancer. Multiple extracellular receptors and internal signaling nodes tightly regulate NK activation. Cyclin-dependent kinases of the mediator complex (CDK8 and CDK19) were described as a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7267496a9a3dfd136c6ecb06ec5a6826
https://doi.org/10.1158/1535-7163.c.6542802.v1
https://doi.org/10.1158/1535-7163.c.6542802.v1
Autor:
Norbert Kraut, Günther R. Adolf, Eric Haaksma, Andreas Zoephel, Stephan K. Zahn, Heather Tye, Matthias Treu, Otmar Schaaf, Alexander Savchenko, Jens Quant, Dirk Kessler, Marco H. Hofmann, Pilar Garin-Chesa, Joshua Apgar, Michael P. Sanderson
Supplementary Materials and Methods, Tables S1 through S3 and Figures S1 and S2 - Supplementary Materials and Methods: The sources, application and dilution of the antibodies used for Western blotting (WB) and immunohistochemical (IHC) analyses in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb6189c7b8fb2d741fdf8290172943c
https://doi.org/10.1158/1535-7163.22503943
https://doi.org/10.1158/1535-7163.22503943