Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andreas, Striebinger"'
Autor:
Bryan Frey, David Holzinger, Keenan Taylor, Dagmar E. Ehrnhoefer, Andreas Striebinger, Sandra Biesinger, Laura Gasparini, Michael J. O’Neill, Florian Wegner, Stefan Barghorn, Günter U. Höglinger, Roland G. Heym
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Tau seed amplification assays (SAAs) directly measure the seeding activity of tau and would therefore be ideal biomarkers for clinical trials targeting seeding-competent tau in Alzheimer’s disease (AD). However, the precise relationship be
Externí odkaz:
https://doaj.org/article/78bf1f0ec959455f9e1ccbfb0ccf720b
Autor:
Bryan Frey, David Holzinger, Keenan Taylor, Dagmar E. Ehrnhoefer, Andreas Striebinger, Sandra Biesinger, Laura Gasparini, Michael J. O’Neill, Florian Wegner, Stefan Barghorn, Günter U. Höglinger, Roland G. Heym
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/116466ed0c3c4ab5a3caa5ae928acbff
Autor:
Lise I. Loberg, Meha Chhaya, Alexander Ibraghimov, Edit Tarcsa, Andreas Striebinger, Andreas Popp, Lili Huang, Frank Oellien, Stefan Barghorn
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
ABT-736 is a humanized monoclonal antibody generated to target a specific conformation of the amyloid-beta (Aβ) protein oligomer. Development of ABT-736 for Alzheimer’s disease was discontinued due to severe adverse effects (AEs) observed in cynom
Externí odkaz:
https://doaj.org/article/54871d30e40440c9ae5713239f79f81b
Autor:
Florie LePrieult, Ina Mairhofer, Karen Bodie, Jonas Hoppe, Marcus W. Meinhardt, Sonja Julier, Gudrun Plotzky, Ebru Ercan-Herbst, Yulia Mordashova, Sandra Biesinger, Miroslav Cik, Kerstin Schlegel, Dagmar E. Ehrnhoefer, Laura Gasparini, Esther Rodriguez-Correa, Mario Mezler, Corinna Klein, Andreas Striebinger, Erica Barini
Publikováno v:
Neurobiology of Aging
In Alzheimer disease, Tau pathology is thought to propagate from cell to cell throughout interconnected brain areas. However, the forms of Tau released into the brain interstitial fluid (ISF) in vivo during the development of Tauopathy and their path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f92276d66580e69c8305127d6ca1b4a
https://doi.org/10.1016/j.neurobiolaging.2021.09.013
https://doi.org/10.1016/j.neurobiolaging.2021.09.013
Autor:
Gerald P. Gellermann, Helga Byrnes, Andreas Striebinger, Kathrin Ullrich, Reinhold Mueller, Heinz Hillen, Stefan Barghorn
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 2, Pp 212-220 (2008)
Soluble Aβ-oligomers are currently discussed as the major causative species for the development of Alzheimer's disease (AD). Consequently, the β-amyloid cascade hypothesis was extended by Aβ-oligomers and their central neuropathogenic role in AD.
Externí odkaz:
https://doaj.org/article/51c2a39a21a648f787f79d80a20ebc29
Autor:
Andreas Popp, Alexander Ibraghimov, Lise I. Loberg, Stefan Barghorn, Lili Huang, Meha Chhaya, Andreas Striebinger, Frank Oellien, Edit Tarcsa
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
ABT-736 is a humanized monoclonal antibody generated to target a specific conformation of the amyloid-beta (Aβ) protein oligomer. Development of ABT-736 for Alzheimer’s disease was discontinued due to severe adverse effects (AEs) observed in cynom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4ba4fc0ee4831893a9c164718462f6
http://europepmc.org/articles/PMC7894423
http://europepmc.org/articles/PMC7894423
Autor:
Andreas Striebinger, Helga Byrnes, Heinz Hillen, Kathrin Ullrich, Reinhold Mueller, Gerald P. Gellermann, Stefan Barghorn
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 2, Pp 212-220 (2008)
Soluble A beta-oligomers are currently discussed as the major causative species for the development of Alzheimer's disease (AD). Consequently, the beta-amyloid cascade hypothesis was extended by A beta-oligomers and their central neuropathogenic role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023c10bec9f6257345471abceab96017
https://doi.org/10.1016/j.nbd.2008.01.010
https://doi.org/10.1016/j.nbd.2008.01.010
Autor:
Michael Bahr, Andreas Striebinger, Ulrich Ebert, John E. Harlan, Eve H. Barlow, Patrick Keller, Heinz Hillen, Carsten Krantz, Volker Nimmrich, Bodo Janson, Stefan Barghorn, Robert S. Bitner, Martin Schmidt
Publikováno v:
Journal of Neurochemistry. 95:834-847
Amyloid b-peptide (Ab)1)42 oligomers have recently been discussed as intermediate toxic species in Alzheimer’s disease (AD) pathology. Here we describe a new and highly stable Ab1)42 oligomer species which can easily be prepared in vitro and is pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f5af21a80973eb18cd6911a3aecdef
https://doi.org/10.1111/j.1471-4159.2005.03407.x
https://doi.org/10.1111/j.1471-4159.2005.03407.x
Autor:
Fred Van Leuven, Heinz Hillen, Hans Schoemaker, Stefan Barghorn, Andreas Striebinger, Marcel M. van Gaalen, James P. Sullivan, Boris Labkovsky, Reinhold Müller, Anton Bespalov, Ingrid Van der Auwera, Claudia Perez-Cruz, Ulrich Ebert, Volker Nimmrich, Marc W. Nolte
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(31)
Oligomers of the β-amyloid (Aβ) peptide have been indicated in early neuropathologic changes in Alzheimer's disease. Here, we present a synthetic Aβ20-42oligomer (named globulomer) with a different conformation to monomeric and fibrillar Aβ pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8696bef7caf9505f8aa84e29ddff3176
https://pubmed.ncbi.nlm.nih.gov/20685980
https://pubmed.ncbi.nlm.nih.gov/20685980
Publikováno v:
Alzheimer's & Dementia. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26d717469f3beb056941a7f51151ba65
https://doi.org/10.1016/j.jalz.2010.05.772
https://doi.org/10.1016/j.jalz.2010.05.772