Zobrazeno 1 - 10 of 53 pro vyhledávání: '"Andreas, Schildan"'
1
Akademický článek
Tau deposition patterns are associated with functional connectivity in primary tauopathies
Autor: Nicolai Franzmeier, Matthias Brendel, Leonie Beyer, Luna Slemann, Gabor G. Kovacs, Thomas Arzberger, Carolin Kurz, Gesine Respondek, Milica J. Lukic, Davina Biel, Anna Rubinski, Lukas Frontzkowski, Selina Hummel, Andre Müller, Anika Finze, Carla Palleis, Emanuel Joseph, Endy Weidinger, Sabrina Katzdobler, Mengmeng Song, Gloria Biechele, Maike Kern, Maximilian Scheifele, Boris-Stephan Rauchmann, Robert Perneczky, Michael Rullman, Marianne Patt, Andreas Schildan, Henryk Barthel, Osama Sabri, Jost J. Rumpf, Matthias L. Schroeter, Joseph Classen, Victor Villemagne, John Seibyl, Andrew W. Stephens, Edward B. Lee, David G. Coughlin, Armin Giese, Murray Grossman, Corey T. McMillan, Ellen Gelpi, Laura Molina-Porcel, Yaroslau Compta, John C. van Swieten, Laura Donker Laat, Claire Troakes, Safa Al-Sarraj, John L. Robinson, Sharon X. Xie, David J. Irwin, Sigrun Roeber, Jochen Herms, Mikael Simons, Peter Bartenstein, Virginia M. Lee, John Q. Trojanowski, Johannes Levin, Günter Höglinger, Michael Ewers
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Tau pathology drives neuronal dysfunction in 4- repeat tauopathies. Here, the authors combine tau-PET, resting-state fMRI and histopathology data, to show that brain connectivity is associated with tau deposition patterns in 4-repeat tauopathies.
Externí odkaz: https://doaj.org/article/bd1a4c237aa0450eb6ad79b56669c4c6
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2
Akademický článek
Superiority of Formalin-Fixed Paraffin-Embedded Brain Tissue for in vitro Assessment of Progressive Supranuclear Palsy Tau Pathology With [18F]PI-2620
Autor: Marie Willroider, Sigrun Roeber, Anja K. E. Horn, Thomas Arzberger, Maximilian Scheifele, Gesine Respondek, Osama Sabri, Henryk Barthel, Marianne Patt, Olena Mishchenko, Andreas Schildan, André Mueller, Norman Koglin, Andrew Stephens, Johannes Levin, Günter U. Höglinger, Peter Bartenstein, Jochen Herms, Matthias Brendel, Leonie Beyer
Publikováno v: Frontiers in Neurology, Vol 12 (2021)
Objectives: Autoradiography on brain tissue is used to validate binding targets of newly discovered radiotracers. The purpose of this study was to correlate quantification of autoradiography signal using the novel next-generation tau positron emissio
Externí odkaz: https://doaj.org/article/204039db83664a75824cf7da9c040999
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3
Akademický článek
Evaluation of early-phase [18F]-florbetaben PET acquisition in clinical routine cases
Autor: Sonja Daerr, Matthias Brendel, Christian Zach, Erik Mille, Dorothee Schilling, Mathias Johannes Zacherl, Katharina Bürger, Adrian Danek, Oliver Pogarell, Andreas Schildan, Marianne Patt, Henryk Barthel, Osama Sabri, Peter Bartenstein, Axel Rominger
Publikováno v: NeuroImage: Clinical, Vol 14, Iss C, Pp 77-86 (2017)
Objectives: In recent years several [18F]-labelled amyloid PET tracers have been developed and have obtained clinical approval. There is accumulating evidence that early (post injection) acquisitions with these tracers are equally informative as conv
Externí odkaz: https://doaj.org/article/f8b638ef9d4741bea6b28682fcc5b68f
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4
Akademický článek
Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results
Autor: Mathias Kranz, Bernhard Sattler, Solveig Tiepolt, Stephan Wilke, Winnie Deuther-Conrad, Cornelius K. Donat, Steffen Fischer, Marianne Patt, Andreas Schildan, Jörg Patt, René Smits, Alexander Hoepping, Jörg Steinbach, Osama Sabri, Peter Brust
Publikováno v: EJNMMI Physics, Vol 3, Iss 1, Pp 1-17 (2016)
Abstract Background Both enantiomers of [18F]flubatine are new radioligands for neuroimaging of α4β2 nicotinic acetylcholine receptors with positron emission tomography (PET) exhibiting promising pharmacokinetics which makes them attractive for dif
Externí odkaz: https://doaj.org/article/22d1a721c89541809a7b0a213fbb9da3
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10
Tau spreading is driven by neuronal connectivity in primary tauopathies - evidence from tau-PET and histopathology
Autor: Sabrina Katzdobler, Carolin Kurz, Robert Perneczky, Joseph Classen, Matthias Brendel, Anna Rubinski, Mikael Simons, Edward B. Lee, Ellen Gelpi, Nicolai Franzmeier, Michael Rullman, Milica Ječmenica Lukić, Günter U. Höglinger, Leonie Beyer, Anika Finze, Claire Troakes, Peter Bartenstein, Corey T. McMillan, John Q. Trojanowski, Maximilian Scheifele, Sigrun Roeber, Osama Sabri, Carla Palleis, Matthias L. Schroeter, John Seybl, David J. Irwin, Sharon X. Xie, Yaroslau Compta, Thomas Arzberger, Mengmeng Song, Emanuel Joseph, Lukas Frontzkowski, Jochen Herms, Michael Ewers, Davina Biel, Endy Weidinger, Laura Donker Laat, Virginia M.-Y. Lee, Laura Molina-Porcel, Victor L. Villemagne, Maike Kern, John L. Robinson, Gloria Biechele, Murray Grossman, Henryk Barthel, Armin Giese, Gabor G. Kovacs, Gesine Respondek, Jost J. Rumpf, Johannes Levin, Andreas Schildan, Boris-Stephan Rauchmann, David G. Coughlin, John C. van Swieten, Marianne Patt, Andrew Stephens, Safa Al-Sarraj
Tau pathology is the main driver of neuronal dysfunction in 4-repeat tauopathies (4RT), including cortico-basal degeneration and progressive supranuclear palsy (PSP). Tau is assumed to spread prion-like across connected neurons, but the mechanisms of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20eb3beba36e859abed9f3396e8e0ad4
https://doi.org/10.1101/2021.08.16.21261523
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