Výsledky vyhledávání - "Andreas, Luegering"

Treat to target versus standard of care for patients with Crohn's disease treated with ustekinumab (STARDUST):an open-label, multicentre, randomised phase 3b trial

Autor: Silvio Danese, Severine Vermeire, Geert D'Haens, Julian Panés, Axel Dignass, Fernando Magro, Maciej Nazar, Manuela Le Bars, Marjolein Lahaye, Lioudmila Ni, Ivana Bravata, Frederic Lavie, Marco Daperno, Milan Lukáš, Alessandro Armuzzi, Mark Löwenberg, Daniel R Gaya, Laurent Peyrin-Biroulet, Rodolfo Rocca, Susana Lopes, Flavio Caprioli, Sandro Ardizzone, Ana Echarri Piudo, Paolo Gionchetti, Xavier Roblin, Ursula Seidler, David Andersson, Kamal Patel, Pierre Desreumaux, Simone Saibeni, Gustav From, Miroslav Fedurco, Milos Gregus, Yoram Bouhnik, Andreas Luegering, Rocco Cosintino, Ivan Bunganic, Jaime Ramos, Mariam Aguas Peris, Olivier Dewit, Mariabeatrice Principi, Emma Wesley, Paula Lago, Stephane Nancey, María Dolores Martín Arranz, Pieter Hindryckx, Ambrogio Orlando, Andrea Geccherle, Maria Laura Annunziata, Bu'hussain Hayee, Jozef Balaz, Francisco Portela, Cyrielle Gilletta, Torsten Kucharzik, Miguel Mínguez, Javier Pérez Gisbert, Ana Gutiérrez Casbas, Edouard Louis, Marco Marino, Gareth Parkes, Fraser Cummings, Bindia Jharap, Jens Kjeldsen, Luís Correia, Paula Ministro, Matthias Ebert, Erik Hertervig, Dirk Staessen, Joris Dutré, Arnaud Colard, Graham Morrison, Henning Glerup, Jens Frederik Dahlerup, Frank Wolfhagen, Marian Batovsky, Martin Molnar, Barbora Kadleckova, Paulo Caldeira, David Laharie, Xavier Hebuterne, Bruno Bonaz, Matthieu Allez, Andreas Fischer, Joaquín Ernesto Hinojosa Del Val, Miriam Mañosa Ciria, Jose Manuel Herrera Justiniano, Charlotte Soderman, Rajiv Chandy, Craig Mowat, Peter Irving, Jan Fallingborg, Jan Matous, Tomas Douda, Romain Altwegg, Jose Manuel Benitez, María Teresa Arroyo Villarino, Jordi Guardiola Capón, Daniel Ginard Vicenc, Pieter Dewint, Sven Almer, Sebastien Kindt

Publikováno v: Danese, S, Vermeire, S, D'Haens, G, Panés, J, Dignass, A, Magro, F, Nazar, M, Le Bars, M, Lahaye, M, Ni, L, Bravata, I, Lavie, F, Daperno, M, Lukáš, M, Armuzzi, A, Löwenberg, M, Gaya, D R, Peyrin-Biroulet, L & STARDUST study group 2022, ' Treat to target versus standard of care for patients with Crohn's disease treated with ustekinumab (STARDUST) : an open-label, multicentre, randomised phase 3b trial ', The Lancet Gastroenterology and Hepatology, vol. 7, no. 4, pp. 294-306 . https://doi.org/10.1016/S2468-1253(21)00474-X
lancet. Gastroenterology & hepatology, 7(4), 294-306. Elsevier Limited
The Lancet Gastroenterology and Hepatology, 7(4), 294-306. Elsevier Ltd

Background: A treat-to-target strategy, in which strictly defined treatment targets facilitate decision making in clinical practice, is advocated as an optimised management approach for some chronic disorders. The aim of the STARDUST trial was to ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c41ea76bc7f88c535499cddcf9ba8ad
https://pure.au.dk/portal/da/publications/treat-to-target-versus-standard-of-care-for-patients-with-crohns-disease-treated-with-ustekinumab-stardust(6e02a521-a146-4afb-857c-d91bbe745a10).html

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Single- vs. double-balloon enteroscopy in small-bowel diagnostics: a randomized multicenter trial

Autor: Ernst J. Kuipers, Huseyin Aktas, Hansjörg Ullerich, Andreas Luegering, T Meister, Philipp Lenz, Lars Aabakken, Michael Bretthauer, Achim Heinecke, Peter Mensink, Wolfram Domschke, Dirk Domagk

Publikováno v: Endoscopy. 43:472-476

Background and study aims Double-balloon enteroscopy (DBE) is the first choice endoscopic technique for small-bowel visualization. However, preparation and handling of the double-balloon enteroscope is complex. Recently, a single-balloon enteroscopy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa18fb6763d5970ac11fe07e399d1a5f
https://doi.org/10.1055/s-0030-1256247

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The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: a randomised study

Autor: Severine Vermeire, Julián Panés, Steven W. Martin, Ulrike Strauch, Gary Craig Burgess, Subrata Ghosh, Jana Sirotiakova, Jens Frederik Dahlerup, Wojciech Niezychowski, Jacqueline Spanton, Andreas Luegering

Publikováno v: Vermeire, S, Ghosh, S, Panes, J, Dahlerup, J F, Luegering, A, Sirotiakova, J, Strauch, U, Burgess, G, Spanton, J, Martin, S W & Niezychowski, W 2011, ' The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis : a randomised study ' Gut, vol. 60, no. 8, pp. 1068-75 . https://doi.org/10.1136/gut.2010.226548

Background and aims Leucocyte migration to gut mucosa, mediated by integrin binding to mucosal addressin cell adhesion molecule (MAdCAM), is a promising target for therapeutic intervention in inflammatory bowel disease. This first-in-human study of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b646335bfef71bae2acf9ad1cce694d4
https://doi.org/10.1136/gut.2010.226548

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Enoxaparin Improves the Course of Dextran Sodium Sulfate-Induced Colitis in Syndecan-1-Deficient Mice

Autor: Andreas Luegering, Martin Götte, Ludwig Kiesel, Wolfram Domschke, Martin K. Wild, Martin Floer, Ezeddin Salem Gassar, Torsten Kucharzik, Jan Heidemann

Publikováno v: The American Journal of Pathology. 176:146-157

Syndecan-1 (Sdc1) plays a major role in wound healing and modulates inflammatory responses. Sdc1 expression is reduced in lesions of patients with ulcerative colitis. The aim of this study was to investigate the role of Sdc1 in murine dextran sodium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b845a2c04e13a8a41b45ec6690f33bce
https://doi.org/10.2353/ajpath.2010.080639

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Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease

Autor: Markus Böhm, Jan Heidemann, Thomas A. Luger, Matthias Ross, Andreas Luegering, Wolfram Domschke, Thomas Brzoska, K Kannengiesser, Christian Maaser, Torsten Kucharzik

Publikováno v: Inflammatory Bowel Diseases. 14:324-331

Background: Despite some progress in recent years, the options for treating inflammatory bowel disease (IBD) are still dissatisfying, and surgery rates are still high. The anti-inflammatory effects of melanocortin peptides such as alpha-melanocyte-st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717fdbee5683da554839ce9769247a6e
https://doi.org/10.1002/ibd.20334

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Preterm birth but not mode of delivery is associated with an increased risk of developing inflammatory bowel disease later in life

Autor: Jan Heidemann, Pia Lebiedz, Andreas Luegering, Emile Rijcken, Achim Heinecke, Birgit Stolze, Barbara Sonntag, Torsten Kucharzik, Wolfram Domschke, Ludwig Kiesel, Christian Maaser

Publikováno v: Inflammatory Bowel Diseases. 13:1385-1390

Background: Exposure to bacterial antigens and other environmental factors in combination with a genetic susceptibility have been implicated in the etiology of inflammatory bowel disease (IBD). As certain perinatal circumstances, e.g., delivery by ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d89f4ae4e4fb2f4c2bc5232de7839e
https://doi.org/10.1002/ibd.20206

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Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms

Autor: Charles A. Parkos, James L. Madara, Torsten Kucharzik, Asma Nusrat, Andreas Luegering, Ann M. Hopkins, Matthias Bruewer

Publikováno v: The Journal of Immunology. 171:6164-6172

It is well known that inflammatory conditions of the intestinal mucosa result in compromised barrier function. Inflammation is characterized by an influx into the mucosa of immune cells that influence epithelial function by releasing proinflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ed0a0a1fb90ffc89ebe73170557284
https://doi.org/10.4049/jimmunol.171.11.6164

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