Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Andreas, Klos"'
Autor:
Jan D. Zemtsovski, Srinu Tumpara, Sonja Schmidt, Vijith Vijayan, Andreas Klos, Robert Laudeley, Julia Held, Stephan Immenschuh, Florian M. Wurm, Tobias Welte, Hermann Haller, Sabina Janciauskiene, Nelli Shushakova
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundExcessive inflammation, hemolysis, and accumulation of labile heme play an essential role in the pathophysiology of multi-organ dysfunction syndrome (MODS) in sepsis. Alpha1-antitrypsin (AAT), an acute phase protein with heme binding capaci
Externí odkaz:
https://doaj.org/article/44b182a20fed4dd3a42717018dafa97b
Autor:
Anna Sophie Heinemann, Jan Lennart Stalp, João Pedro Pereira Bonifacio, Filo Silva, Maike Willers, Julia Heckmann, Beate Fehlhaber, Lena Völlger, Dina Raafat, Nicole Normann, Andreas Klos, Gesine Hansen, Mirco Schmolke, Dorothee Viemann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Infections with influenza A viruses (IAV) cause seasonal epidemics and global pandemics. The majority of these infections remain asymptomatic, especially among children below five years of age. Importantly, this is a time, when immunological imprinti
Externí odkaz:
https://doaj.org/article/5cfe06f96a78426fa17ed1b8aec8978f
Autor:
Marcel Muenstermann, Lea Strobel, Andreas Klos, Rick A. Wetsel, Trent M. Woodruff, Jörg Köhl, Kay O. Johswich
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 677-694 (2019)
The complement system is pivotal in the defense against invasive disease caused by Neisseria meningitidis (Nme, meningococcus), particularly via the membrane attack complex. Complement activation liberates the anaphylatoxins C3a and C5a, which activa
Externí odkaz:
https://doaj.org/article/cee52e09e9124ecf9d47d1030abd7b3f
Autor:
Martin Kohn, Christian Lanfermann, Robert Laudeley, Silke Glage, Claudia Rheinheimer, Andreas Klos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Recent advances in complement research have revolutionized our understanding of its role in immune responses. The immunomodulatory features of complement in infections by intracellular pathogens, e.g., viruses, are attracting increasing attention. Th
Externí odkaz:
https://doaj.org/article/b5ab872e6bd64e61a2a0264ec84170df
Autor:
Martin Kohn, Christian Lanfermann, Robert Laudeley, Silke Glage, Claudia Rheinheimer, Andreas Klos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The zoonotic intracellular bacterium Chlamydia psittaci causes life-threatening pneumonia in humans. During mouse lung infection, complement factor C3 and the anaphylatoxin C3a augment protection against C. psittaci by a so far unknown mechanism. To
Externí odkaz:
https://doaj.org/article/be82d8c155d14cc78dda86fa517786d6
Publikováno v:
Vaccines, Vol 9, Iss 8, p 871 (2021)
Chlamydia trachomatis causes most bacterial sexually transmitted diseases worldwide. Different major outer membrane proteins (MOMPs) define various serovars of this intracellular pathogen: In women, D to L3 can cause urethritis, cervicitis, salpingit
Externí odkaz:
https://doaj.org/article/7a18ccb353674e48bc0b38e0b86b944d
Autor:
Christian Lanfermann, Sebastian Wintgens, Thomas Ebensen, Martin Kohn, Robert Laudeley, Kai Schulze, Claudia Rheinheimer, Johannes H. Hegemann, Carlos Alberto Guzmán, Andreas Klos
Publikováno v:
Vaccines, Vol 9, Iss 6, p 609 (2021)
Chlamydia trachomatis is the most frequent sexually-transmitted disease-causing bacterium. Urogenital serovars of this intracellular pathogen lead to urethritis and cervicitis. Ascending infections result in pelvic inflammatory disease, salpingitis,
Externí odkaz:
https://doaj.org/article/58475f704f05430bbf6420ed8f041d22
Publikováno v:
International Journal of Networking and Computing. 12:164-187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041fa713c77a9d5d2340d1a8f8b0397c
https://doi.org/10.15803/ijnc.12.1_164
https://doi.org/10.15803/ijnc.12.1_164
Autor:
Johannes B. Herrmann, Marcel Muenstermann, Lea Strobel, Alexandra Schubert-Unkmeir, Trent M. Woodruff, Scott D. Gray-Owen, Andreas Klos, Kay O. Johswich
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Sepsis caused by Neisseria meningitidis (meningococcus) is a rapidly progressing, life-threatening disease. Because its initial symptoms are rather unspecific, medical attention is often sought too late, i.e., when the systemic inflammatory
Externí odkaz:
https://doaj.org/article/8d5ddfe44f84454f96d7562df509f7ab
Publikováno v:
Pathogens, Vol 4, Iss 4, Pp 722-738 (2015)
The complement anaphylatoxin C5a contributes to host defense against Staphylococcus aureus. In this study, we investigated the functional role of the two known C5a receptors, C5aR1 and C5aR2, in the host response to S. aureus. We found that C5aR1−/
Externí odkaz:
https://doaj.org/article/536932877bca4055ab7f1da09b5e8205