Occurrence and effects of octreotide antibodies during nasal, subcutaneous and slow release intramuscular treatment

Autor: Jørgen Weeke, Hans Ørskov, Andreas Kaal, Steen Nielsen, Peter Marbach, Alberto M Pedroncelli, Ioana Lancranjan

Publikováno v: European Journal of Endocrinology. :353-361

OBJECTIVE: Previous studies have indicated that antibody formation against octreotide is extremely rare. We examined the occurrence of octreotide antibody formation after treatment with three administration forms in large populations of patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018faa3fe2f450897a8076c40c4313df
https://doi.org/10.1530/eje.0.1430353

Effects of intramuscular microsphere-encapsulated octreotide on serum growth hormone, insulin-like growth factors (IGFs), free IGFs, and IGF-binding proteins in acromegalic patients

Autor: Jørgen Weeke, C. Skjærbæk, Ioana Lancranjan, S. Nielsen, Peter Marbach, Jens Otto Lunde Jørgensen, C. Bruns, Andreas Kaal, Jan Frystyk, Hans Ørskov

Publikováno v: Metabolism. 44:6-14

Nine acromegalic patients selected to be well-controlled on subcutaneous octreotide injections three times daily were transferred for more than 1 year to intramuscular injections every month with a new microsphere-encapsulated octreotide formulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::534d051ba23e19f192b436e22ef84432
https://doi.org/10.1016/0026-0495(95)90304-6

A randomized comparison of intranasal and injectable octreotide administration in patients with acromegaly

Autor: Hans Ørskov, P. Illum, Jørgen Weeke, M. Mau Pedersen, Andreas Kaal, S. E. Christensen, A. G. Harris

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 75:163-169

Fifteen acromegalic patients received four single doses of octreotide in random order (500 micrograms, 1000 micrograms, and 2000 micrograms applied intranasally and 100 micrograms given sc). Serum octreotide and GH data were subjected to pharmacokine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49e1a4c7c1ff05ce5342309d8c8c21d
https://doi.org/10.1210/jcem.75.1.1619006

Muscle GLUT4 in cirrhosis

Autor: Rolf Dall, Ole Schmitz, Andreas Kaal, Lars Vinter-Jensen, Per Heden Andersen, Sten Lund, Steen B. Pedersen, Hendrik Vilstrup, Peter Holland-Fischer, Michael F. Nielsen

Publikováno v: Aarhus University
Holland-Fischer, P, Andersen, P H, Lund, S, Pedersen, S B, Vinter-Jensen, L, Nielsen, M F, Kaal, A, Dall, R, Schmitz, O & Vilstrup, H 2007, ' Muscle GLUT4 in cirrhosis ', J. Hepatol., vol. 47, no. 2, pp. 212-9 .
Holland-Fischer, P, Andersen, P H, Lund, S, Pedersen, S B, Vinter-Jensen, L, Nielsen, M F, Kaal, A, Dall, R, Schmitz, O & Vilstrup, H 2007, ' Muscle GLUT4 in cirrhosis ', Journal of Hepatology, vol. 47, no. 2, pp. 212-219 . https://doi.org/10.1016/j.jhep.2007.02.012

Udgivelsesdato: 2007-Aug BACKGROUND/AIMS: The insulin-dependent glucose transporter GLUT4 mediates 50-80% of whole body glucose uptake, but its relation to the frequent glucose intolerance in patients with liver cirrhosis is unknown. METHODS: Thirty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3206c6bca3334c95e184009ce8cf9d97
https://pubmed.ncbi.nlm.nih.gov/17448565

Evaluation of growth hormone stimulation tests in cured acromegalic patients

Autor: Mario Vaisman, Sanne Fisker, Flavia Lucia Conceição, Jens Sandahl Christiansen, Marianne Andersen, Jens Otto Lunde Jørgensen, Andreas Kaal

Publikováno v: Growth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 13(6)

We have evaluated the GH peak response to insulin tolerance test (ITT) and to GHRH+arginine in 11 patients cured of acromegaly after treatment with surgery/radiotherapy and compared them to a control group matched for age and sex. GH peak response wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8f1a2a27e07160a3f4bb6007481458
https://pubmed.ncbi.nlm.nih.gov/14624769