Zobrazeno 1 - 10
of 583
pro vyhledávání: '"Andreas, Hofmann"'
Autor:
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R. Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H. Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R. Thoma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/1168651eade84aa68bb9c377c9befbde
Autor:
Merve Mutlu, Isabel Schmidt, Andrew I. Morrison, Benedikt Goretzki, Felix Freuler, Damien Begue, Oliver Simic, Nicolas Pythoud, Erik Ahrne, Sandra Kapps, Susan Roest, Debora Bonenfant, Delphine Jeanpierre, Thi-Thanh-Thao Tran, Rob Maher, Shaojian An, Amandine Rietsch, Florian Nigsch, Andreas Hofmann, John Reece-Hoyes, Christian N. Parker, Danilo Guerini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stimulator of interferon genes (STING) is a central component of the cytosolic nucleic acids sensing pathway and as such master regulator of the type I interferon response. Due to its critical role in physiology and its’ involvement in a v
Externí odkaz:
https://doaj.org/article/d64305878b7f4abe9dd92a3040e7b4f4
Autor:
Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zoller, Sandrine Ferrand, Francois Gauter, Xiaoyan Li, Frederic Sigoillot, Scott Gleim, Therese-Marie Stachyra, Jason R. Thomas, Damien Begue, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Henault, John Alford, Erik Ahrne, Luca Tordella, Greg Hollingworth, Nicolas H. Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R. Thoma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Targeted protein degradation (TPD) mediates protein level through small molecule induced redirection of E3 ligases to ubiquitinate neo-substrates and mark them for proteasomal degradation. TPD has recently emerged as a key modality in drug d
Externí odkaz:
https://doaj.org/article/8f2eff537f564b01931321a688bb396a
Autor:
Harrison T. Shanley, Aya C. Taki, Nghi Nguyen, Tao Wang, Joseph J. Byrne, Ching-Seng Ang, Michael G. Leeming, Shuai Nie, Nicholas Williamson, Yuanting Zheng, Neil D. Young, Pasi K. Korhonen, Andreas Hofmann, Bill C.H. Chang, Tim N.C. Wells, Cécile Häberli, Jennifer Keiser, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 24, Iss , Pp 100522- (2024)
Within the context of our anthelmintic discovery program, we recently identified and evaluated a quinoline derivative, called ABX464 or obefazimod, as a nematocidal candidate; synthesised a series of analogues which were assessed for activity against
Externí odkaz:
https://doaj.org/article/bd1202bcf63a4ff0ade2f378a914072b
Autor:
Fatema-Zahra M. Rashid, Frédéric G. E. Crémazy, Andreas Hofmann, David Forrest, David C. Grainger, Dieter W. Heermann, Remus T. Dame
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Nucleoid associated proteins (NAPs) maintain the architecture of bacterial chromosomes and regulate gene expression. Thus, their role as transcription factors may involve three-dimensional chromosome re-organisation. While this model is supp
Externí odkaz:
https://doaj.org/article/e5591af993724439831c95bd12cafc31
Autor:
Hajo Groneberg, Sven Oberdiek, Carolin Schulz, Andreas Hofmann, Alexander Schloske, Frank Doepper
Publikováno v:
Journal of Manufacturing and Materials Processing, Vol 8, Iss 4, p 158 (2024)
The additive manufacturing technology powder bed fusion of metal with a laser beam (PBF-LB/M) is industrially established for tool-free production of complex and individualized components and products. While the in-processing is based on a layer-by-l
Externí odkaz:
https://doaj.org/article/3bd100ba9a954cbc99a8abd6799ef9e5
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract Knowledge about capacity losses related to the solid electrolyte interphase (SEI) in sodium‐ion batteries (SIBs) is still limited. One major challenge in SIBs is that the solubility of SEI species in liquid electrolytes is comparatively hi
Externí odkaz:
https://doaj.org/article/43d21ab548af42099f61795a1279e1bf
Publikováno v:
Journal of Manufacturing and Materials Processing, Vol 8, Iss 3, p 112 (2024)
Achieving a homogeneous and uniform powder bed surface as well as a defined, uniform layer thickness is crucial for achieving reproducible component properties that meet requirements when powder bed fusion of metals with a laser beam. The existing re
Externí odkaz:
https://doaj.org/article/18b038e651e34f6184b2c6ff8bd9c758
Autor:
Lukas Engel, Danti Khouri, Konstantin Lomakin, Andreas Hofmann, Micha Kleinlein, Ingrid Ullmann, Martin Vossiek, Gerald Gold
Publikováno v:
IEEE Open Journal of Antennas and Propagation, Vol 4, Pp 558-570 (2023)
Nowadays, additive manufacturing provides far-reaching possibilities for use in radio frequency components. In addition to almost unlimited freedom of design as compared to conventional manufacturing, the absence of further assembly steps is a key as
Externí odkaz:
https://doaj.org/article/e92fa038855c440db237f33999c254b4
Publikováno v:
Advanced Science, Vol 10, Iss 24, Pp n/a-n/a (2023)
Abstract This study addresses the improved cycling stability of Li‐ion batteries based on Fe–Ti‐doped LiNi0.5Mn1.5O4 (LNMO) high‐voltage cathode active material and graphite anodes. By using 1 wt% Li3PO4 as cathode additive, over 90% capacity
Externí odkaz:
https://doaj.org/article/77ed170c1c2e4f15ad1150943d1ad87f