Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Andreas, Hocke"'
Autor:
Simon Schroeder, Christin Mache, Hannah Kleine-Weber, Victor M. Corman, Doreen Muth, Anja Richter, Diana Fatykhova, Ziad A. Memish, Megan L. Stanifer, Steeve Boulant, Mitra Gultom, Ronald Dijkman, Stephan Eggeling, Andreas Hocke, Stefan Hippenstiel, Volker Thiel, Stefan Pöhlmann, Thorsten Wolff, Marcel A. Müller, Christian Drosten
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
MERS-CoV is enzootic in dromedary camels, can spread to humans but undergoes limited onward transmission. Here, Schroeder et al. compare clinical isolates of MERS-CoV in vitro and show that the predominantly circulating recombinant lineage 5 possess
Externí odkaz:
https://doaj.org/article/fd5899e1e8ed4fc68c3c88e1bf84f1a6
Autor:
Susanne Krasemann, Carsten Dittmayer, Saskia von Stillfried, Jenny Meinhardt, Fabian Heinrich, Kristin Hartmann, Susanne Pfefferle, Edda Thies, Regina von Manitius, Tom Alex David Aschman, Josefine Radke, Anja Osterloh, Simone Schmid, Eva Miriam Buhl, Jana Ihlow, Frank Dubois, Viktor Arnhold, Sefer Elezkurtaj, David Horst, Andreas Hocke, Sara Timm, Sebastian Bachmann, Victor Corman, Hans-Hilmar Goebel, Jakob Matschke, Stephanie Stanelle-Bertram, Gülsah Gabriel, Danielle Seilhean, Homa Adle-Biassette, Benjamin Ondruschka, Matthias Ochs, Werner Stenzel, Frank L. Heppner, Peter Boor, Helena Radbruch, Michael Laue, Markus Glatzel
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104193- (2022)
Summary: Background: Autopsy studies have provided valuable insights into the pathophysiology of COVID-19. Controversies remain about whether the clinical presentation is due to direct organ damage by SARS-CoV-2 or secondary effects, such as overshoo
Externí odkaz:
https://doaj.org/article/8c3f588c9dc544439b18fd7f7d5e9f6b
Autor:
Aline da Rocha Matos, Katharina Wunderlich, Sebastian Schloer, Klaus Schughart, Robert Geffers, Martine Seders, Marlous de Witt, Anmari Christersson, Rainer Wiewrodt, Karsten Wiebe, Peter Barth, Andreas Hocke, Stefan Hippenstiel, Katja Hönzke, Ulf Dittmer, Kathrin Sutter, Ursula Rescher, Svetlana Rodionycheva, Nicoletta Matera, Stephan Ludwig, Linda Brunotte
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1763-1776 (2019)
ABSTRACTInfluenza is an acute respiratory infection causing high morbidity and mortality in annual outbreaks worldwide. Antiviral drugs are limited and pose the risk of resistance development, calling for new treatment options. IFN-α subtypes are im
Externí odkaz:
https://doaj.org/article/846368ab325d404ba94cc3b595911cc2
Autor:
Emanuel Wyler, Kirstin Mösbauer, Vedran Franke, Asija Diag, Lina Theresa Gottula, Roberto Arsiè, Filippos Klironomos, David Koppstein, Katja Hönzke, Salah Ayoub, Christopher Buccitelli, Karen Hoffmann, Anja Richter, Ivano Legnini, Andranik Ivanov, Tommaso Mari, Simone Del Giudice, Jan Papies, Samantha Praktiknjo, Thomas F. Meyer, Marcel Alexander Müller, Daniela Niemeyer, Andreas Hocke, Matthias Selbach, Altuna Akalin, Nikolaus Rajewsky, Christian Drosten, Markus Landthaler
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102151- (2021)
Summary: Detailed knowledge of the molecular biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host responses, and disease progression. Here, we report gene expression
Externí odkaz:
https://doaj.org/article/aa494f159d1e4728b02c9632c197db4f
Autor:
Nico Halwe, Lea Hamberger, Julia Sehl-Ewert, Christin Mache, Jacob Schön, Lorenz Ulrich, Sten Calvelage, Jonas Fuchs, Pooja Bandawane, Madhumathi Loganathan, Anass Abbad, Juan Manuel Carreño, Viviana Simon, Ghazi Kayali, Mario Tönnies, Ahmed Kandeil, Rabeh El-Shesheny, Mohamed Ali, Thorsten Wolff, Matthias Budt, Stefan Hippenstiel, Andreas Hocke, Florian Krammer, Martin Schwemmle, Kevin Ciminski, Donata Hoffmann, Maria Bermudez-Gonzalez, Martin Beer
An Old-World bat H9N2 influenza A virus (IAV) identified in Egypt exhibits high replication and transmission potential in ferrets, efficient infection of human lung explant cultures and marked escape from the antiviral activity of MxA. Together with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09c7ef7139d99638f46f3219c8b22928
https://doi.org/10.21203/rs.3.rs-2937503/v1
https://doi.org/10.21203/rs.3.rs-2937503/v1
Autor:
Patrick Graff, Stefan Hönzke, Aaroh Anand Joshi, Guy Yealland, Emanuel Fleige, Michael Unbehauen, Monika Schäfer-Korting, Andreas Hocke, Rainer Haag, Sarah Hedtrich
Publikováno v:
Molecular Pharmaceutics. 19:1795-1802
Human skin equivalents emerged as novel tools in preclinical dermatological research. It is being claimed that they may bridge the translational gap between preclinical and clinical research, yet only a few studies have investigated their suitability
Autor:
Aileen Faist, Sebastian Schloer, Angeles Mecate-Zambrano, Josua Janowski, André Schreiber, Yvonne Boergeling, Beate C.G. Conrad, Sriram Kumar, Leonie Toebben, Klaus Schughart, Morris Baumgardt, Mirjana Kessler, Katja Hoenzke, Andreas Hocke, Marcel Trautmann, Wolfgang Hartmann, Hiroki Kato, Ursula Rescher, Anmari Christersson, Joachim Kuehn, Alexander Mellmann, Thorsten Wolff, Philip Kuempers, Alexandros Rovas, Rainer Wiewrodt, Karsten Wiebe, Peter Barth, Stephan Ludwig, Linda Brunotte
Publikováno v:
Antiviral research. 209
SARS-CoV-2 is the causative agent of the immune response-driven disease COVID-19 for which new antiviral and anti-inflammatory treatments are urgently needed to reduce recovery time, risk of death and long COVID development. Here, we demonstrate that
Autor:
Umer Bin Abdul Aziz, Marcel Bermudez, Maren Mieth, Ali Saoud, Thomas Rudolf, Christoph Arkona, Christoph Böttcher, Kai Ludwig, Andreas Hocke, Gerhard Wolber, Jörg Rademann
Pneumolysin (PLY) is a pore-forming, cholesterol-dependent cytolysin (CDC) from Streptococcus pneumoniae, the main bacterial cause for community-acquired pneumonia. Liberation of PLY during host infection leads to strong immune activation and cytolyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf770df6fe13660674e9526f10f54b86
https://doi.org/10.26434/chemrxiv-2022-fx0d2
https://doi.org/10.26434/chemrxiv-2022-fx0d2
Autor:
Lasti Erfinanda, Lin Zou, Birgitt Gutbier, Disi Lei, Katrin Reppe, Luiz Gustavo Teixeira Alves, Laura Kneller, Bill Schneider, Laura Michalick, Diana Fatykhova, Paul Schneider, Wolfgang Liedtke, Eisei Sohara, Timothy J. Mitchell, Andreas Hocke, Stefan Hippenstiel, Marcus A. Mall, Martin Witzenrath, Wolfgang M. Kuebler
Publikováno v:
The FASEB Journal. 36
Autor:
Ronja Mothes, Anna Pascual-Reguant, Ralf Koehler, Juliane Liebeskind, Alina Liebheit, Sandy Bauherr, Carsten Dittmayer, Michael Laue, Regina von Manitius, Sefer Elezkurtaj, Pawel Durek, Frederik Heinrich, Gitta Anne Heinz, Gabriela Maria Guerra, Benedikt Obermayer, Jenny Meinhardt, Jana Ihlow, Josefine Radke, Frank L. Heppner, Philipp Enghard, Helena Stockmann, Tom Aschman, Julia Schneider, Victor Corman, Leif Erik Sander, Mir-Farzin Mashreghi, Thomas Conrad, Andreas Hocke, Raluca A. Niesner, Helena Radbruch, Anja E. Hauser
Post-acute lung sequelae of COVID-19 are challenging many survivors across the world, yet the mechanisms behind are poorly understood. Our results delineate an inflammatory cascade of events occurring along disease progression within fibrovascular ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cec82aaf6c768375804a73d0e6beea0
https://doi.org/10.1101/2022.03.24.22272768
https://doi.org/10.1101/2022.03.24.22272768