Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Andreas, Bruns"'
Publikováno v:
Cell Reports, Vol 20, Iss 8, Pp 1867-1880 (2017)
The NMDA receptor (NMDAR) antagonist ketamine elicits a long-lasting antidepressant response in patients with treatment-resistant depression. Understanding how antagonism of NMDARs alters synapse and circuit function is pivotal to developing circuit-
Externí odkaz:
https://doaj.org/article/5f4a90a5441040d284ff9eac8da96f05
Autor:
Andreas Bruns
The talk gives a very short introduction into some of the themes within the ethics of data sharing. What are (some of) the ethical questions surrounding data sharing and use? What is the relationship between ethics and other normative domains, such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0f2e2d3496fa766d71f5591b86dd73
Autor:
Andreas Bruns
Publikováno v:
The Good Place and Philosophy. :87-96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f842bafe445a72818bcd5c88e7bc90e
https://doi.org/10.1002/9781119633303.ch9
https://doi.org/10.1002/9781119633303.ch9
Autor:
Dany V D'Souza, Elisabeth Jonckers, Andreas Bruns, Basil Künnecke, Markus von Kienlin, Annemie Van der Linden, Thomas Mueggler, Marleen Verhoye
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106156 (2014)
Translation of resting-state functional connectivity (FC) magnetic resonance imaging (rs-fMRI) applications from human to rodents has experienced growing interest, and bears a great potential in pre-clinical imaging as it enables assessing non-invasi
Externí odkaz:
https://doaj.org/article/a2a3e1ea172c4f3a908ce0c7e6a21089
Autor:
Schnider Patrick, Erwin Goetschi, Neil Parrott, Hasane Ratni, Markus von Kienlin, Basil Künnecke, Celine Risterucci, Cosimo Dolente, Mark Rogers-Evans, Roland Jakob-Roetne, Christophe Grundschober, Andreas Bruns, Caterina Bissantz, Emmanuel Pinard, Wolfgang Muster, Thomas Mueggler
Publikováno v:
Journal of medicinal chemistry. 63(4)
We recently reported the discovery of a potent, selective, and brain-penetrant V1a receptor antagonist, which was not suitable for full development. Nevertheless, this compound was found to improve surrogates of social behavior in adults with autism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b81a9362ac94dbb48af9cbb342a3c3
https://pubmed.ncbi.nlm.nih.gov/31951127
https://pubmed.ncbi.nlm.nih.gov/31951127
Autor:
Anirvan Ghosh, Madhurima Benekareddy, Basil Künnecke, Andreas Bruns, Frédéric Knoflach, Tevye J. Stachniak, Markus von Kienlin
Publikováno v:
Biological Psychiatry. 83:607-617
Background The prefrontal cortex (PFC) has been implicated in the pathophysiology of social dysfunction, but the specific circuit partners mediating PFC function in health and disease are unclear. Methods The excitatory designer receptor exclusively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea6ec9696e68c0b1c5d718d3fc1ab20
https://doi.org/10.1016/j.biopsych.2017.10.032
https://doi.org/10.1016/j.biopsych.2017.10.032
Autor:
Silvia Gatti, Ernesto Fedele, Lorenzo Morè, Veronica Bianchi, Basil Künnecke, Patrizia D'Adamo, Latefa Yekhlef, Andreas Bruns, Antonella Marte, Stefano Taverna
Publikováno v:
Neuroscience
Highlights • Attention and stimulus selection deficits in Gdi1-null Intellectual Disability model. • Behavioral deficits correlated with fronto-striatal system dysfunction. • A major role for glutamatergic activity in fronto-striatal circuitry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9f2ba073055b6633bbd1e28fd2b0b1
Autor:
Will Spooren, Jamie Horder, Declan G. Murphy, Marija M. Petrinovic, Toru Takumi, Maria Andreina Mendez, Andreas Bruns, Gareth J. Barker, Basil Künnecke
Publikováno v:
Translational Psychiatry
Horder, J, Petrinovic, M M, Mendez, M A, Bruns, A, Takumi, T, Spooren, W, Barker, G J, Kuennecke, B & Murphy, D G 2018, ' Glutamate and GABA in autism spectrum disorder – A translational magnetic resonance spectroscopy study in man and rodent models ', Translational psychiatry, vol. 8, no. 1, 106, pp. 1-11 . https://doi.org/10.1038/s41398-018-0155-1
Translational Psychiatry, Vol 8, Iss 1, Pp 1-11 (2018)
Horder, J, Petrinovic, M M, Mendez, M A, Bruns, A, Takumi, T, Spooren, W, Barker, G J, Kuennecke, B & Murphy, D G 2018, ' Glutamate and GABA in autism spectrum disorder – A translational magnetic resonance spectroscopy study in man and rodent models ', Translational psychiatry, vol. 8, no. 1, 106, pp. 1-11 . https://doi.org/10.1038/s41398-018-0155-1
Translational Psychiatry, Vol 8, Iss 1, Pp 1-11 (2018)
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high human and economic burden. The pathophysiology of ASD is largely unclear, thus hampering development of pharmacological treatments for the core symptoms of the diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05bac1d5123a11536aae11eb29aa9a8
http://europepmc.org/articles/PMC5970172
http://europepmc.org/articles/PMC5970172
Autor:
Murray B. Stein, Amanda Bischoff-Grethe, Andreas Bruns, Thomas T. Liu, Markus von Kienlin, Christina E. Wierenga, Gregory G. Brown, Alan N. Simmons, Susanne Ostrowitzki, Orah Y. Stein, Martin P. Paulus
Publikováno v:
Psychiatry Research: Neuroimaging. 233:394-401
This study investigated the temporal pattern of brain response to emotional stimuli during 28 days of alprazolam treatment among patients with generalized anxiety disorder (GAD) randomized 2:1 to drug or placebo in a double-blind design. Functional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114938899e5604e4e12acc4c12e4464e
https://doi.org/10.1016/j.pscychresns.2015.06.016
https://doi.org/10.1016/j.pscychresns.2015.06.016
Depression is a pervasive and debilitating neuropsychiatric disorder. A single, low dose of the NMDA receptor (NMDAR) antagonist ketamine elicits a long-lasting antidepressant response in patients with treatment-resistant major depressive disorder. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05b0df00a77941cb5b2ddddc545d953
https://doi.org/10.1101/106419
https://doi.org/10.1101/106419