Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Andreas, Bjorefeldt"'
Autor:
Mansi Prakash, Jeremy Murphy, Robyn St Laurent, Nina Friedman, Emmanuel L. Crespo, Andreas Bjorefeldt, Akash Pal, Yuvraj Bhagat, Julie A. Kauer, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Prakash et al. develop an approach to control synaptically connected elements using bioluminescent light, in which Luciferase-generated light, originating from a presynaptic axon terminal, modulates an opsin in its postsynaptic target to form an ‘o
Externí odkaz:
https://doaj.org/article/466740bf581a4a9e9e4cf7688016fe99
Autor:
Emmanuel L. Crespo, Mansi Prakash, Andreas Bjorefeldt, William E. Medendorp, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100667- (2021)
Summary: Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG thus confers both optogenetic and chemogenetic access within the same genetically ta
Externí odkaz:
https://doaj.org/article/3c21176793034b0dae2223b29eebc3f3
Autor:
William E. Medendorp, Andreas Bjorefeldt, Emmanuel L. Crespo, Mansi Prakash, Akash Pal, Madison L. Waddell, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102157- (2021)
Summary: In genetic and pharmacological models of neurodevelopmental disorders, and human data, neural activity is altered within the developing neocortical network. This commonality begs the question of whether early enhancement in excitation might
Externí odkaz:
https://doaj.org/article/2fac34280f43468297b5619b71767bfc
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
The cerebrospinal fluid (CSF) occupies the brain’s ventricles and subarachnoid space and, together with the interstitial fluid (ISF), forms a continuous fluidic network that bathes all cells of the central nervous system (CNS). As such, the CSF is
Externí odkaz:
https://doaj.org/article/c1b0cacbdb74494480582a6907075d9d
Autor:
Nathan C. Shaner, Ute Hochgeschwender, Mansi Prakash, Julie A. Kauer, Emmanual Crespo, Andreas Bjorefeldt, Akash Pal, Nina Friedman, Diane Lipscombe, Robyn St Laurent, Jeremy W. Murphy, Yuvraj Bhagat, Christopher I. Moore
Publikováno v:
Communications Biology
Communications biology, vol 5, iss 1
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Communications biology, vol 5, iss 1
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Understanding percepts, engrams and actions requires methods for selectively modulating synaptic communication between specific subsets of interconnected cells. Here, we develop an approach to control synaptically connected elements using bioluminesc
Publikováno v:
Journal of visualized experiments : JoVE. (174)
Bioluminescence - light emitted by a luciferase enzyme oxidizing a small molecule substrate, a luciferin - has been used in vitro and in vivo to activate light-gated ion channels and pumps in neurons. While this bioluminescent optogenetics (BL-OG) ap
Publikováno v:
Journal of Visualized Experiments.
Bioluminescence - light emitted by a luciferase enzyme oxidizing a small molecule substrate, a luciferin - has been used in vitro and in vivo to activate light-gated ion channels and pumps in neurons. While this bioluminescent optogenetics (BL-OG) ap
Publikováno v:
Hippocampus. 30:101-113
Gamma oscillations (30-80 Hz) are fast network activity patterns frequently linked to cognition. They are commonly studied in hippocampal brain slices in vitro, where they can be evoked via pharmacological activation of various receptor families. One
Autor:
Pontus Wasling, My Forsberg, Henrik Seth, Henrik Zetterberg, Tim Lyckenvik, Eric Hanse, Andreas Bjorefeldt, Mats Andersson
Publikováno v:
Journal of Neurochemistry. 149:452-470
It is well-known that the extracellular concentration of calcium affects neuronal excitability and synaptic transmission. Less is known about the physiological concentration of extracellular calcium in the brain. In electrophysiological brain slice e
Autor:
Akash Pal, Ute Hochgeschwender, Andreas Bjorefeldt, Christopher I. Moore, Madison L. Waddell, William E. Medendorp
SummaryIn leading models of Autism Spectrum Disorder, and in human data, the efficacy of outgoing cortical connectivity transitions from overly exuberant to languid from early development to adulthood. This transition begs the question of whether the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b87f554b6869faa7f530089cdfede
https://doi.org/10.1101/2020.01.18.911347
https://doi.org/10.1101/2020.01.18.911347