Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Andreas, Bergthaler"'
Autor:
Valentina Stolz, Rafael de Freitas e Silva, Ramona Rica, Ci Zhu, Teresa Preglej, Patricia Hamminger, Daniela Hainberger, Marlis Alteneder, Lena Müller, Monika Waldherr, Darina Waltenberger, Anastasiya Hladik, Benedikt Agerer, Michael Schuster, Tobias Frey, Thomas Krausgruber, Sylvia Knapp, Clarissa Campbell, Klaus Schmetterer, Michael Trauner, Andreas Bergthaler, Christoph Bock, Nicole Boucheron, Wilfried Ellmeier
Publikováno v:
eLife, Vol 13 (2024)
FOXP3+ regulatory T cells (Treg cells) are key for immune homeostasis. Here, we reveal that nuclear receptor corepressor 1 (NCOR1) controls naïve and effector Treg cell states. Upon NCOR1 deletion in T cells, effector Treg cell frequencies were elev
Externí odkaz:
https://doaj.org/article/99b838b47ea54f90b5aa68be8607b3a8
Autor:
Angelika Wagner, Erika Garner-Spitzer, Claudia Auer, Pia Gattinger, Ines Zwazl, René Platzer, Maria Orola-Taus, Peter Pichler, Fabian Amman, Andreas Bergthaler, Johannes B. Huppa, Hannes Stockinger, Christoph C. Zielinski, Rudolf Valenta, Michael Kundi, Ursula Wiedermann
Publikováno v:
Vaccines, Vol 12, Iss 5, p 518 (2024)
Patients with multiple myeloma (MM) are a heterogenous, immunocompromised group with increased risk for COVID-19 morbidity and mortality but impaired responses to primary mRNA SARS-CoV-2 vaccination. The effects of booster vaccinations and breakthrou
Externí odkaz:
https://doaj.org/article/26083936ad8646f7a8062db04cd5010d
Autor:
Johanna Klughammer, Daria Romanovskaia, Amelie Nemc, Annika Posautz, Charlotte A. Seid, Linda C. Schuster, Melissa C. Keinath, Juan Sebastian Lugo Ramos, Lindsay Kosack, Ann Evankow, Dieter Printz, Stefanie Kirchberger, Bekir Ergüner, Paul Datlinger, Nikolaus Fortelny, Christian Schmidl, Matthias Farlik, Kaja Skjærven, Andreas Bergthaler, Miriam Liedvogel, Denise Thaller, Pamela A. Burger, Marcela Hermann, Martin Distel, Daniel L. Distel, Anna Kübber-Heiss, Christoph Bock
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
DNA methylation is involved in regulatory processes throughout the animal kingdom. Here, the authors map DNA methylation in 535 vertebrates and 45 invertebrates, establishing a reference dataset for cross-species analysis and exploring epigenetic var
Externí odkaz:
https://doaj.org/article/a66c803083214c8fba3343238e70ba59
Autor:
Askar Gafurov, Andrej Baláž, Fabian Amman, Kristína Boršová, Viktória Čabanová, Boris Klempa, Andreas Bergthaler, Tomáš Vinař, Broňa Brejová
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background The genomes of SARS-CoV-2 are classified into variants, some of which are monitored as variants of concern (e.g. the Delta variant B.1.617.2 or Omicron variant B.1.1.529). Proportions of these variants circulating in a human popul
Externí odkaz:
https://doaj.org/article/4d6e5715ac914ed79120dc987e8ddf00
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112829- (2023)
In this issue of Cell Reports, Redford et al.1 uncouple the role of CD4+ and CD8+ T cells in controlling anorexia and wasting of muscle and adipose tissue during chronic parasitic infections. These results shed light on the impact of adaptive immune
Externí odkaz:
https://doaj.org/article/ad3a6c4ca89e462a8f407b9cdb567469
Autor:
Tea Pemovska, Johannes W. Bigenzahn, Ismet Srndic, Alexander Lercher, Andreas Bergthaler, Adrián César-Razquin, Felix Kartnig, Christoph Kornauth, Peter Valent, Philipp B. Staber, Giulio Superti-Furga
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Metabolic reprogramming contributes to cancer development and progression. Here, the authors show the utility of a metabolic drug library to uncover metabolic vulnerabilities and obtain functional insights into myeloid leukemia biology.
Externí odkaz:
https://doaj.org/article/7885abd3f4f445118af188dbf35853b8
Autor:
Haifeng C. Xu, Ruifeng Wang, Prashant V. Shinde, Lara Walotka, Anfei Huang, Gereon Poschmann, Jun Huang, Wei Liu, Kai Stühler, Heiner Schaal, Andreas Bergthaler, Aleksandra A. Pandyra, Cornelia Hardt, Karl S. Lang, Philipp A. Lang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Using different strains of the lymphocytic choriomeningitis virus (LCMV), Xu, Wang et al. show that a slow viral propagation limits type I interferon (IFN-I) production and viral persistence in mice. This study suggests a reduced viral propagation as
Externí odkaz:
https://doaj.org/article/e64f13b539b04accba130bd3d10b5844
Autor:
Enrico Girardi, Gennaro Agrimi, Ulrich Goldmann, Giuseppe Fiume, Sabrina Lindinger, Vitaly Sedlyarov, Ismet Srndic, Bettina Gürtl, Benedikt Agerer, Felix Kartnig, Pasquale Scarcia, Maria Antonietta Di Noia, Eva Liñeiro, Manuele Rebsamen, Tabea Wiedmer, Andreas Bergthaler, Luigi Palmieri, Giulio Superti-Furga
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Maintenance of a mitochondrial NAD+ pool is critical for cellular life, yet the existence and identity of the transporter responsible for mitochondrial NAD+ uptake was unknown until recently. Here, the authors use genomic, genetic, and metabolomic ap
Externí odkaz:
https://doaj.org/article/e8ac6a683e1a429f8d643e2061a12835
Autor:
Riem Gawish, Philipp Starkl, Lisabeth Pimenov, Anastasiya Hladik, Karin Lakovits, Felicitas Oberndorfer, Shane JF Cronin, Anna Ohradanova-Repic, Gerald Wirnsberger, Benedikt Agerer, Lukas Endler, Tümay Capraz, Jan W Perthold, Domagoj Cikes, Rubina Koglgruber, Astrid Hagelkruys, Nuria Montserrat, Ali Mirazimi, Louis Boon, Hannes Stockinger, Andreas Bergthaler, Chris Oostenbrink, Josef M Penninger, Sylvia Knapp
Publikováno v:
eLife, Vol 11 (2022)
Despite tremendous progress in the understanding of COVID-19, mechanistic insight into immunological, disease-driving factors remains limited. We generated maVie16, a mouse-adapted SARS-CoV-2, by serial passaging of a human isolate. In silico modelin
Externí odkaz:
https://doaj.org/article/c49137ed8a364fa0b46437d84e5c0342
Autor:
Jasmina Panovska-Griffiths, Chris Griffiths, Andrea Siebenhofer, Christoph Bock, Werner Leber, Karin Stiasny, Oliver Lammel, Monika Redlberger-Fritz, Maria Elisabeth Mustafa-Korninger, Reingard Christina Glehr, Jeremy Camp, Benedikt Agerer, Alexander Lercher, Alexandra Popa, Jakob-Wendelin Genger, Thomas Penz, Stephan Aberle, Andreas Bergthaler, Eva-Maria Hochstrasser, Christian Hoellinger
Publikováno v:
BMJ Open, Vol 11, Iss 8 (2021)
Objectives We explore the importance of SARS-CoV-2 sentinel surveillance testing in primary care during a regional COVID-19 outbreak in Austria.Design Prospective cohort study.Setting A single sentinel practice serving 22 829 people in the ski-resort
Externí odkaz:
https://doaj.org/article/e01625da1827485099aa773e68ed83e3