Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges.

Autor: Andreani T; Chemistry Research Centre (CIQUP) and Institute of Molecular Sciences (IMS), Department of Chemistry and Biochemistry, Faculty of Sciences of University of Porto, Rua Do Campo Alegre s/n, 4169-007, Porto, Portugal.; GreenUPorto-Sustainable Agrifood Production Research Centre & Inov4Agro, Department of Biology, Faculty of Sciences of University of Porto, Rua Campo Alegre s/n, 4169-007, Porto, Portugal., Cheng R; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, FI-00014, Helsinki, Finland.; Department of Biomaterials and Biomedical Technology, The Personalized Medicine Research Institute Groningen (PRECISION), University Medical Center Groningen, University of Groningen, 9713 AV, Groningen, The Netherlands., Elbadri K; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, FI-00014, Helsinki, Finland., Ferro C; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, FI-00014, Helsinki, Finland.; Research Institute for Medicines, iMed.Ulisboa, Faculty of Pharmacy, Universidade de Lisboa, 1649-003, Lisbon, Portugal., Menezes T; Chemistry Research Centre (CIQUP) and Institute of Molecular Sciences (IMS), Department of Chemistry and Biochemistry, Faculty of Sciences of University of Porto, Rua Do Campo Alegre s/n, 4169-007, Porto, Portugal., Dos Santos MR; Chemistry Research Centre (CIQUP) and Institute of Molecular Sciences (IMS), Department of Chemistry and Biochemistry, Faculty of Sciences of University of Porto, Rua Do Campo Alegre s/n, 4169-007, Porto, Portugal., Pereira CM; Chemistry Research Centre (CIQUP) and Institute of Molecular Sciences (IMS), Department of Chemistry and Biochemistry, Faculty of Sciences of University of Porto, Rua Do Campo Alegre s/n, 4169-007, Porto, Portugal., Santos HA; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, FI-00014, Helsinki, Finland. h.a.santos@umcg.nl.; Department of Biomaterials and Biomedical Technology, The Personalized Medicine Research Institute Groningen (PRECISION), University Medical Center Groningen, University of Groningen, 9713 AV, Groningen, The Netherlands. h.a.santos@umcg.nl.

Publikováno v: Drug delivery and translational research [Drug Deliv Transl Res] 2024 Oct; Vol. 14 (10), pp. 2845-2916. Date of Electronic Publication: 2024 Jul 13.

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DiSiR: fast and robust method to identify ligand-receptor interactions at subunit level from single-cell RNA-sequencing data.

Autor: Vahid MR; Sanofi R&D Data and Data Science, Artificial Intelligence & Deep Analytics, Omics Data Science, 450 Water Street, Cambridge, MA 02142, USA., Kurlovs AH; Sanofi R&D, Precision Medicine and Computational Biology, 350 Water Street, Cambridge, MA 02142, USA., Andreani T; Sanofi R&D Data and Data Science, Artificial Intelligence & Deep Analytics, Omics Data Science, Frankfurt am Main 65926, Germany., Augé F; Sanofi R&D Data and Data Science, Artificial Intelligence & Deep Analytics, Omics Data Science, 1, Av Pierre Brossolette 91385, Chilly-Mazarin, France., Olfati-Saber R; Sanofi R&D Data and Data Science, Artificial Intelligence & Deep Analytics, Omics Data Science, 450 Water Street, Cambridge, MA 02142, USA., de Rinaldis E; Sanofi R&D, Precision Medicine and Computational Biology, 350 Water Street, Cambridge, MA 02142, USA., Rapaport F; Sanofi R&D Data and Data Science, Artificial Intelligence & Deep Analytics, Omics Data Science, 450 Water Street, Cambridge, MA 02142, USA.; Sanofi R&D, Precision Medicine and Computational Biology, 350 Water Street, Cambridge, MA 02142, USA., Savova V; Sanofi R&D, Precision Medicine and Computational Biology, 350 Water Street, Cambridge, MA 02142, USA.

Publikováno v: NAR genomics and bioinformatics [NAR Genom Bioinform] 2023 Mar 23; Vol. 5 (1), pp. lqad030. Date of Electronic Publication: 2023 Mar 23 (Print Publication: 2023).

Expression and subcellular localization of USH1C/harmonin in human retina provides insights into pathomechanisms and therapy.

Autor: Nagel-Wolfrum K; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.; Institute of Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Fadl BR; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA., Becker MM; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Wunderlich KA; Department of Physiological Genomics, BioMedical Center, Ludwig-Maximilian University Munich, 82152 Planegg-Martinsried, Germany., Schäfer J; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Sturm D; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.; Institute of Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Fritze J; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Gür B; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Kaplan L; Department of Physiological Genomics, BioMedical Center, Ludwig-Maximilian University Munich, 82152 Planegg-Martinsried, Germany., Andreani T; Computational Biology and Data Mining, Institute of Organismic & Molecular Evolution Biology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Goldmann T; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Brooks M; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA., Starostik MR; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA., Lokhande A; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA., Apel M; Department of Ophthalmology, University Medical Centre Mainz, 55131 Mainz, Germany., Fath KR; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.; Department of Biology, Queens College of CUNY, Kissena Blvd, Flushing, NY 11367, USA., Stingl K; University Eye Hospital, Centre for Ophthalmology, University of Tubingen, 72076 Tubingen, Germany., Kohl S; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tubingen, 72076 Tubingen, Germany., DeAngelis MM; Department of Ophthalmology and Ira G. Ross Eye Institute, Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, NY 14209, USA., Schlötzer-Schrehardt U; Department of Ophthalmology, Friedrich-Alexander-Universität, Erlangen-Nürnberg, 91054 Erlangen, Germany., Kim IK; Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA., Owen LA; Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT 84132, USA., Vetter JM; Department of Ophthalmology, University Medical Centre Mainz, 55131 Mainz, Germany., Pfeiffer N; Department of Ophthalmology, University Medical Centre Mainz, 55131 Mainz, Germany., Andrade-Navarro MA; Computational Biology and Data Mining, Institute of Organismic & Molecular Evolution Biology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Grosche A; Department of Physiological Genomics, BioMedical Center, Ludwig-Maximilian University Munich, 82152 Planegg-Martinsried, Germany., Swaroop A; Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA., Wolfrum U; Institute of Molecular Physiology, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2023 Jan 13; Vol. 32 (3), pp. 431-449.