Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andreane Cartier"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tumor progression is dependent on angiogenesis, which supplies nutrients and enables gas exchange and metastatic dissemination. However, tumor vessels are dysfunctional and immature, which hinders the effectiveness of various therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e544f1dd67e3a7f9c50e8734326b43
https://doi.org/10.1073/pnas.1906246117
https://doi.org/10.1073/pnas.1906246117
Autor:
Steven Swendeman, Daniel Lin, Shihui Guo, Alan Culbertson, Andrew Kuo, Michel Levesque, Andreane Cartier, Takahiro Seno, Alec Schmaier, Sylvain Galvani, Asuka Inoue, Samir Parikh, Garret A. FitzGerald, Maofu Liao, Robert Flaumenhaft, Timothy Hla
High-density lipoprotein (HDL) particles suppress inflammation-induced tissue injury via vascular and myeloid cell-dependent mechanisms. As such, HDL-associated bioactive lipids such as sphingosine 1-phosphate (S1P) and prostacyclin (PGI2) signal via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4005c5cbaf5588791118de103b09a16
https://doi.org/10.1101/2022.02.14.480375
https://doi.org/10.1101/2022.02.14.480375
Autor:
Alicia Franklin, Katharine E. Black, Barry S. Shea, Patricia L. Brazee, Benjamin D. Medoff, Jason W. Griffith, Andreane Cartier, Francesca Giacona, Andrew Kuo, Elizabeth A Abe, Clemens K Probst, Rachel S. Knipe, Matt Drummond, Lida P. Hariri, Christina Christoffersen, Andrew M. Tager, Amanda Logue, Eric Engelbrecht, Sydney B. Montesi, Timothy Hla, Jillian J Spinney
Publikováno v:
Am J Respir Cell Mol Biol
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease which leads to significant morbidity and mortality from respiratory failure. The two drugs currently approved for clinical use slow the rate of decline in lung function but have no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67d11fc3fdced4d69fa7beeeb07c905
https://pubmed.ncbi.nlm.nih.gov/34343038
https://pubmed.ncbi.nlm.nih.gov/34343038
Autor:
Koki Kawakami, Junken Aoki, Andreane Cartier, Andrew Kuo, Wenji Piao, Yanbao Xiong, Keisuke Yanagida, Satoru Ishida, Timothy Hla, Jonathan S. Bromberg, Sylvain Galvani, Yu Hisano, Mari Kono, Asuka Inoue, Richard L. Proia, Yuki Ono, Kuniyuki Kano, Eric Engelbrecht
Publikováno v:
The Journal of Experimental Medicine
Sphingosine 1-phosphate receptor-1 signaling via the Gi pathway is suppressed by lysophosphatidic acid receptor-1, which recruits β-arrestin to the heterotypic receptor complex. This mechanism occurs at sinus lining lymphatic endothelial cells of ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9806caec5142cf2ec3b61439e550e490
https://doi.org/10.1084/jem.20181895
https://doi.org/10.1084/jem.20181895
Sphingosine 1-phosphate receptor-1 (S1PR1) is essential for embryonic vascular development and maturation. In the adult, it is a key regulator of vascular barrier function and inflammatory processes. Its roles in tumor angiogenesis, tumor growth and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c843331e7ed86c2548ed8fc2d53ebbd6
Autor:
Yanbao Xiong, Joseph M. Kulinski, Timothy Hla, Bruce R. Blazar, Jonathan S. Bromberg, Keli L. Hippen, Lushen Li, Susan R. Schwab, C. Colin Brinkman, Ana Olivera, Andreane Cartier, Wenji Piao
Publikováno v:
Science Immunology. 4
Sphingosine 1-phosphate (S1P) and S1P receptors (S1PRs) regulate migration of lymphocytes out of thymus to blood and lymph nodes (LNs) to efferent lymph, whereas their role in other tissue sites is not known. Here, we investigated the question of how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159d1cc5fb21b675374bf44eb05f183a
https://doi.org/10.1126/sciimmunol.aav1263
https://doi.org/10.1126/sciimmunol.aav1263
Autor:
Koki Kawakami, Junken Aoki, Andrew Kuo, Eric Engelbrecht, Keisuke Yanagida, Satoru Ishida, Andreane Cartier, Yuki Ono, Timothy Hla, Mari Kono, Asuka Inoue, Richard L. Proia, Sylvain Galvani, Yu Hisano
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) activate G protein-coupled receptors (GPCRs) to regulate key pathobiological processes. Here we report a novel lipid mediator GPCR cross-talk mechanism that modulates lymphatic endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b43c71144a8d9c83e6cb72dc7dacf6d
Autor:
Hideru Obinata, Anna Cantalupo, Annarita Di Lorenzo, Sylvain Galvani, Nathalie Burg, Keisuke Yanagida, Catherine H. Liu, Steven L. Swendeman, Timothy Hla, Teresa Sanchez, Hui Yuan, Yi Zhang, Victoria A. Blaho, Eric Engelbrecht, Andreane Cartier, Yu Hisano, Yuquan Xiong, Jane E. Salmon
Publikováno v:
Science signaling. 10(492)
Endothelial dysfunction, a hallmark of vascular disease, is restored by plasma high-density lipoprotein (HDL). However, a generalized increase in HDL abundance is not beneficial, suggesting that specific HDL species mediate protective effects. Apolip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea5af25d2bfce83248921f5675e13fc
https://pubmed.ncbi.nlm.nih.gov/28811382
https://pubmed.ncbi.nlm.nih.gov/28811382