Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Andrea Zieris"'
Autor:
Sabine A. Eming, Carsten Werner, Kandice R. Levental, Karolina Chwalek, Manfred F. Maitz, Mikhail V. Tsurkan, Passant Atallah, Andrea Zieris, Uwe Freudenberg
Publikováno v:
Journal of Controlled Release. 220:79-88
While vascular endothelial growth factor (VEGF) has been shown to be one of the key players in wound healing by promoting angiogenesis current clinical applications of this growth factor to the wound environment are poorly controlled and not sustaina
Autor:
Andrea Zieris, Ralf Zimmermann, Carsten Werner, Jens-Uwe Sommer, Uwe Freudenberg, Anika Röhrich, Ron Dockhorn, Martin Müller, Petra B. Welzel, Mikhail V. Tsurkan
Publikováno v:
Biomacromolecules. 15:4439-4446
Sulfation patterns of glycosaminoglycans (GAG) govern the electrostatic complexation of biomolecules and thus allow for modulating the release profiles of growth factors from GAG-based hydrogels. To explore options related to this, selectively desulf
Autor:
Carsten Werner, Silvana Prokoph, Uwe Freudenberg, Stefanie Dimmeler, Andrea Zieris, Kandice R. Levental, Emmanouil Chavakis
Publikováno v:
Biomaterials. 33:4792-4800
Enrichment of progenitor cells in ischemic tissue has become a promising therapeutic strategy in the treatment of myocardial infarction. Towards this aim, we report a biology-inspired concept using sulfated glycosaminoglycans to sustainably generate
Autor:
Katja Schneider, Andrea Zieris, Uwe Freudenberg, Marina Prewitz, Ron Dockhorn, Jens-Uwe Sommer, Silvana Prokoph, Carsten Werner, Karolina Chwalek, Petra B. Welzel, Kandice R. Levental
Publikováno v:
Advanced Functional Materials. 22:1391-1398
Cell-instructive characteristics of extracellular matrices (ECM) resulting from a subtle balance of biomolecular and biophysical signals must be recapitulated in engineered biomaterials to facilitate regenerative therapies. However, no material explo
Autor:
Karolina Chwalek, Kandice R. Levental, Petra B. Welzel, Andrea Zieris, Silvana Prokoph, Uwe Freudenberg, Carsten Werner
Publikováno v:
Scopus-Elsevier
article i nfo Article history: Effective vascularization is a prerequisite for the success of various different tissue engineering concepts. While simultaneous administration of basic fibroblast growth factor (FGF-2) and vascular endothelial growth f
Autor:
Petra B. Welzel, Carsten Werner, Silvana Prokoph, Uwe Freudenberg, Andrea Zieris, Milauscha Grimmer, Kandice R. Levental
Publikováno v:
Biomaterials. 31:7985-7994
Tissue engineering therapies require biomaterials capable of encouraging an angiogenic response. To dissect the influence of different pro-angiogenic stimuli a set of starPEG-heparin hydrogels with varied physicochemical properties was used as a high
Autor:
Andreas Hermann, Andrea Zieris, Katja Stirl, Milauscha Grimmer, Alexander Storch, Woranan Panyanuwat, Sigrid C. Schwarz, Uwe Freudenberg, Dorit Meinhold, Stefan Zschoche, Petra B. Welzel, Carsten Werner
Publikováno v:
Biomaterials. 30:5049-5060
Biofunctional matrices for in vivo tissue engineering strategies must be modifiable in both biomolecular composition and mechanical characteristics. To address this challenge, we present a modular system of biohybrid hydrogels based on covalently cro
Autor:
Andreas Hermann, Katja Schurig, Alexander Storch, Carsten Werner, Milauscha Grimmer, Uwe Freudenberg, Sabine Heidel, Andrea Zieris
Publikováno v:
Biomaterials 67, 205-213 (2015). doi:10.1016/j.biomaterials.2015.07.029
Current cell replacement therapies in Parkinson's disease (PD) are limited by low survival of transplanted cell and lacking regeneration of neuronal circuitries. Therefore, bioartificial cell carriers and growth/differentiation factors are applied to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca4ab595d68dffc47a9d4d8da320f8e
https://pub.dzne.de/record/138111
https://pub.dzne.de/record/138111
Autor:
Kandice R. Levental, Karolina Chwalek, Uwe Freudenberg, Carsten Werner, Andrea Zieris, Silvana Prokoph, Mikhail V. Tsurkan
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 25(18)
Poly(ethylene glycol)-peptide- and glycosaminoglycan-peptide conjugates obtained by a regio-selective amino acid protection strategy are converted into cell-instructive hydrogel matrices capable of inducing morphogenesis in embedded human vascular en
Autor:
Raquel Carvalhosa, Mikhail V. Tsurkan, Benedetta Bussolati, Carsten Werner, Giovanni Camussi, Peter Hauser, Andrea Zieris, Uwe Freudenberg
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 167(3)
Local delivery of growth factors (GFs) can accelerate regeneration of injured tissue, but for many medical applications, injectable GF delivery systems are required for clinical success. Viscoelastic, injectable aggregates of micrometer-sized hydroge