Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Andrea Wilderman"'
Autor:
Andrea Wilderman, Eva D’haene, Machteld Baetens, Tara N. Yankee, Emma Wentworth Winchester, Nicole Glidden, Ellen Roets, Jo Van Dorpe, Sandra Janssens, Danny E. Miller, Miranda Galey, Kari M. Brown, Rolf W. Stottmann, Sarah Vergult, K. Nicole Weaver, Samantha A. Brugmann, Timothy C. Cox, Justin Cotney
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Craniofacial abnormalities account for approximately one third of birth defects. The regulatory programs that build the face require precisely controlled spatiotemporal gene expression, achieved through tissue-specific enhancers. Clusters of
Externí odkaz:
https://doaj.org/article/d8bfbb8f7d514cd7a8d154657d67b4ca
Autor:
Tara N. Yankee, Sungryong Oh, Emma Wentworth Winchester, Andrea Wilderman, Kelsey Robinson, Tia Gordon, Jill A. Rosenfeld, Jennifer VanOudenhove, Daryl A. Scott, Elizabeth J. Leslie, Justin Cotney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Craniofacial disorders arise in early pregnancy and are one of the most common congenital defects. To fully understand how craniofacial disorders arise, it is essential to characterize gene expression during the patterning of the craniofacia
Externí odkaz:
https://doaj.org/article/8fb52a1254b34d8ba4d504c9a78dcfc6
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1581-1597 (2018)
Summary: Defects in patterning during human embryonic development frequently result in craniofacial abnormalities. The gene regulatory programs that build the craniofacial complex are likely controlled by information located between genes and within
Externí odkaz:
https://doaj.org/article/ef9b291610dd4d43a14dcaa93d116b33
Autor:
Katarina Klepac, Ana Kilić, Thorsten Gnad, Loren M. Brown, Beate Herrmann, Andrea Wilderman, Aileen Balkow, Anja Glöde, Katharina Simon, Martin E. Lidell, Matthias J. Betz, Sven Enerbäck, Jürgen Wess, Marc Freichel, Matthias Blüher, Gabi König, Evi Kostenis, Paul A. Insel, Alexander Pfeifer
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Brown and beige adipose tissues contribute to organismal energy expenditure by generating heat. Here, Klepac et al. survey G protein-coupled receptors in brown fat and show that Gq-coupled receptors inhibit expression of thermogenic proteins in mice
Externí odkaz:
https://doaj.org/article/7a2bc9f5eaee4df68bf0b1b7a219eba3
Autor:
Paul A. Insel, Krishna Sriram, Shu Z. Wiley, Andrea Wilderman, Trishna Katakia, Thalia McCann, Hiroshi Yokouchi, Lingzhi Zhang, Ross Corriden, Dongling Liu, Michael E. Feigin, Randall P. French, Andrew M. Lowy, Fiona Murray
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
G protein-coupled receptors (GPCRs), the largest family of targets for approved drugs, are rarely targeted for cancer treatment, except for certain endocrine and hormone-responsive tumors. Limited knowledge regarding GPCR expression in cancer cells l
Externí odkaz:
https://doaj.org/article/28de7d53db774f9b8b4d7ba1fda6c2d8
Autor:
Andrea Wilderman, Eva D’haene, Machteld Baetens, Tara N. Yankee, Emma Wentworth Winchester, Nicole Glidden, Ellen Roets, Jo Van Dorpe, Sarah Vergult, Timothy C. Cox, Justin Cotney
Defects in embryonic patterning resulting in craniofacial abnormalities account for approximately 1/3 of birth defects. The regulatory programs that build and shape the face require precisely controlled spatiotemporal gene expression, achieved throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b4ca502a6eea2605e2f8f2e36b8c3e3
https://doi.org/10.1101/2022.03.10.483852
https://doi.org/10.1101/2022.03.10.483852
Autor:
Tara N. Yankee, Andrea Wilderman, Emma Wentworth Winchester, Jennifer VanOudenhove, Justin Cotney
SummaryCraniofacial disorders are among the most common of all congenital defects. A majority of craniofacial development occurs early in pregnancy and to fully understand how craniofacial defects arise, it is essential to observe gene expression dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::220201b00a98fa1e6b9fd6bc00af3c78
https://doi.org/10.1101/2022.02.28.482338
https://doi.org/10.1101/2022.02.28.482338
Autor:
Noelle D. Germain, Justin Cotney, Christopher Stoddard, Stormy J. Chamberlain, Andrea Wilderman, Jack S. Hsiao, Geno J Villafano, Leighton J. Core, Luke A Wojenski
Publikováno v:
Proceedings of the National Academy of Sciences. 116:2181-2186
Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by the loss of function from the maternal allele of UBE3A , a gene encoding an E3 ubiquitin ligase. UBE3A is only expressed from the maternally inherited allele in mature human neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0711ad5925222d31c1c00317c427ef65
https://doi.org/10.1073/pnas.1815279116
https://doi.org/10.1073/pnas.1815279116
Publikováno v:
Circ Res
Rationale: There is growing evidence that common variants and rare sequence alterations in regulatory sequences can result in birth defects or predisposition to disease. Congenital heart defects are the most common birth defect and have a clear genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5589f4bdf82c2c306e02e6eb47b3acb
https://pubmed.ncbi.nlm.nih.gov/33031028
https://pubmed.ncbi.nlm.nih.gov/33031028
Publikováno v:
Cell Reports, Vol 23, Iss 5, Pp 1581-1597 (2018)
Cell reports
Cell reports
SUMMARY Defects in patterning during human embryonic development frequently result in craniofacial abnormalities. The gene regulatory programs that build the craniofacial complex are likely controlled by information located between genes and within i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f233b2f3ab6ed1916725f5b2b2541b
https://doi.org/10.1016/j.celrep.2018.03.129
https://doi.org/10.1016/j.celrep.2018.03.129